EP0021441B1 - Elektronenbeschleuniger zur Röntgenstrahlentherapie - Google Patents
Elektronenbeschleuniger zur Röntgenstrahlentherapie Download PDFInfo
- Publication number
- EP0021441B1 EP0021441B1 EP80103661A EP80103661A EP0021441B1 EP 0021441 B1 EP0021441 B1 EP 0021441B1 EP 80103661 A EP80103661 A EP 80103661A EP 80103661 A EP80103661 A EP 80103661A EP 0021441 B1 EP0021441 B1 EP 0021441B1
- Authority
- EP
- European Patent Office
- Prior art keywords
- electron
- energy
- filter plate
- target
- low
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000006096 absorbing agent Substances 0.000 claims description 23
- 239000000463 material Substances 0.000 claims description 15
- 230000005855 radiation Effects 0.000 claims description 14
- 230000001133 acceleration Effects 0.000 claims description 11
- 238000010521 absorption reaction Methods 0.000 claims description 9
- 229910052782 aluminium Inorganic materials 0.000 claims description 7
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 claims description 7
- 238000010894 electron beam technology Methods 0.000 claims description 7
- 229910001385 heavy metal Inorganic materials 0.000 claims description 5
- 238000002560 therapeutic procedure Methods 0.000 claims description 3
- 239000004411 aluminium Substances 0.000 claims 1
- 238000010276 construction Methods 0.000 description 3
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 2
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 2
- 229910052770 Uranium Inorganic materials 0.000 description 2
- 238000001816 cooling Methods 0.000 description 2
- 229910052802 copper Inorganic materials 0.000 description 2
- 239000010949 copper Substances 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 2
- 229910052737 gold Inorganic materials 0.000 description 2
- 239000010931 gold Substances 0.000 description 2
- 229910052751 metal Inorganic materials 0.000 description 2
- 239000002184 metal Substances 0.000 description 2
- 238000007920 subcutaneous administration Methods 0.000 description 2
- 229910052715 tantalum Inorganic materials 0.000 description 2
- GUVRBAGPIYLISA-UHFFFAOYSA-N tantalum atom Chemical compound [Ta] GUVRBAGPIYLISA-UHFFFAOYSA-N 0.000 description 2
- WFKWXMTUELFFGS-UHFFFAOYSA-N tungsten Chemical compound [W] WFKWXMTUELFFGS-UHFFFAOYSA-N 0.000 description 2
- 229910052721 tungsten Inorganic materials 0.000 description 2
- 239000010937 tungsten Substances 0.000 description 2
- 238000011144 upstream manufacturing Methods 0.000 description 2
- JFALSRSLKYAFGM-UHFFFAOYSA-N uranium(0) Chemical compound [U] JFALSRSLKYAFGM-UHFFFAOYSA-N 0.000 description 2
- 229910001369 Brass Inorganic materials 0.000 description 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
- 239000010951 brass Substances 0.000 description 1
- 239000002826 coolant Substances 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 239000011888 foil Substances 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 229910002804 graphite Inorganic materials 0.000 description 1
- 239000010439 graphite Substances 0.000 description 1
- 229910052742 iron Inorganic materials 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000035515 penetration Effects 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 230000009993 protective function Effects 0.000 description 1
- 238000001959 radiotherapy Methods 0.000 description 1
- 229910000679 solder Inorganic materials 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 230000001629 suppression Effects 0.000 description 1
- 239000002918 waste heat Substances 0.000 description 1
Images
Classifications
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J35/00—X-ray tubes
-
- G—PHYSICS
- G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
- G21K—TECHNIQUES FOR HANDLING PARTICLES OR IONISING RADIATION NOT OTHERWISE PROVIDED FOR; IRRADIATION DEVICES; GAMMA RAY OR X-RAY MICROSCOPES
- G21K1/00—Arrangements for handling particles or ionising radiation, e.g. focusing or moderating
- G21K1/10—Scattering devices; Absorbing devices; Ionising radiation filters
Definitions
- the invention relates to a low-energy electron accelerator for X-ray therapy with an evacuated acceleration tube, with a target exposed to the electron beam made of a material with a high atomic number, with a collimator, with a profiled compensating body arranged centered on the axis of symmetry of the collimator's aperture and with a filter plate.
- the device on which the above-mentioned DE-A-2 727 275 is based is to use a deflection magnet which deflects it by 270 ° and focuses the electrons of predetermined energy in the electron beam. In this way, the target is only hit by electrons of the respectively set (high) acceleration energy. This significantly improves the radiation quality.
- a deflection magnet is extremely complex in its construction and also requires a correspondingly large space between the beam exit window of the acceleration tube and the target. This in turn affects the size of the accelerator in an undesirable manner.
- a deflection magnet will therefore only be provided for electron accelerators that achieve a relatively high energy. A certain inhomogeneity of the energy distribution over the radiation cross-section at different penetration depths can be accepted, since at the high energies under consideration tissue is to be attacked not far in the subcutaneous area, but far below.
- Such a high-energy linear accelerator with a deflection magnet should not be considered in the following.
- the electron accelerator mentioned at the outset is known from the reference “Radiology” 115, pages 475-477, May 1975. This works with an X-ray energy of 4 MeV and does not need a magnet.
- the acceleration tube is followed by a target that generates X-rays when electrons collide. After passing through a primary collimator, this strikes a profiled compensating body which consists of a heavy metal, namely lead. After the throughput of an ionization chamber and a secondary collimator, the X-rays fall on a disk-shaped filter, which is made of a low-order metal, namely brass.
- This filter is intended to remove an unpleasant property of such a low-energy electron accelerator; namely, it is said to level the so-called “hot spots” or “horns” in the energy distribution of the X-ray beam measured across the cross section.
- These "hot spots” or “Hömer” can lead to increased doses and thus to burns during therapy in the subcutaneous area.
- This filter therefore selectively reduces the areas with a high radiation dose at the edges of large radiation fields.
- Such a solution to the problem of "hot spots” or “horns” cannot be used according to the protective provisions of a number of countries that the dose and dose rate changed by the additional filter are not recorded by the monitor.
- DE-A-2 533 348 relates to a target which is composed of three layers. While the first layer consists of a medium atomic number material and is used to generate X-rays, the middle layer consists of a material of low atomic number and serves as an electron absorber. As the last layer, this layer is followed by one made of a material with a high atomic number, which is preferably used to absorb X-ray quanta of lower energy. The use of linear accelerators with low energy is not dealt with in this reference.
- DE-B-2441 986 discloses a large aperture x-ray generator that generates a wide, diffuse x-ray cone.
- the target is applied to a low atomic number plate, preferably aluminum, and there is an aluminum window behind this support plate.
- This publication does not show that the support plate or the window have a function other than allowing the X-ray radiation of the target to pass through well.
- the invention has for its object an electron accelerator of the beginning ge named type, which does not need a magnet and works with an electron energy in the range of 2 to 10 MeV, so that the hardening of the X-rays is achieved with the simplest possible means and at the same time the most uniform possible energy distribution over the radiation cross-section, whereby a practical solution is found should.
- the compensating body is made from a material of a low atomic number
- an electron absorber known per se is connected downstream of the target
- the filter plate is inserted between the electron absorber and the compensating body and is made of heavy metal with high absorption for low-energy X-rays and with low absorption for higher-energy X-rays, the filter plate having an equivalent lead of at least 1 mm at an electron energy of 2 to 10 MeV.
- the compensating body made of a material with a higher atomic number, such as. B. of copper or even lead. Hardening of the X-rays by the compensating body would then have led to an undesired hardening which decreases radially in the cone of radiation due to the different thickness of the profiled compensating body.
- the filter plate is not hit by electrons because of the upstream electron absorber. It cannot therefore appear as a competing target. Under this condition, the choice of filter material can only be based on its suitability for hardening the X-rays. In addition, the compensation body downstream of the filter plate in the beam direction is hit by X-rays, which is largely homogenized by the upstream filter plate.
- a particularly simple construction results if the target is attached to the side of the electron absorber facing the acceleration tube.
- the electron absorber supports whose dimensions must be kept much stronger than that of generally only about 3 mm. strong lead foil existing target, this off. This construction therefore results in an improved mechanical protective function.
- the figure shows a sectional view through the last two cavity resonators of an acceleration tube, through the target and through the collimator.
- the two last, cavity-shaped cavity resonators 1, 2 of an acceleration tube 3 of a linear accelerator are shown cut open along their axis of symmetry 4.
- the axis of symmetry of the cavity resonators coincides with the electron beam 5.
- the outlet opening 6 of the last cavity 2 is closed by a metal plate with high thermal conductivity, the electron absorber 7, in the exemplary embodiment a 20 mm thick copper plate.
- This electron absorber 7 is the last resonant cavity 2 gas-tight up - soldered.
- the electron absorber 7 At the location of the electron absorber 7 where the electron beam 5 would strike, it is provided with a disk-shaped depression, into which a target 8 only a few tenths of a millimeter thick is soldered.
- the electron absorber 7 is provided with cooling channels (not shown) which end in hose connections 9, 10 for connection to a cooling system (not shown here for the sake of clarity).
- the electron absorber 7 carries a filter plate 11 on the side facing away from the target 8.
- the collimator 12 is arranged with a conical opening 13 for the passage of the maximum X-ray field 14 to be used .
- a compensating body 15 is fastened to the collimator 12, by means of which the intensity profile of the X-ray radiation following a Gaussian distribution curve is compensated for over the entire cross-section of the X-ray field 14 that is maximally used.
- the electrons accelerated by the acceleration tube 3 strike the target 8 which closes the exit opening 6 of the acceleration tube 3.
- X-ray brake radiation is generated in the target.
- the waste heat generated in the target is released to the electron absorber via the solder connection between the target 8 and the electron absorber 7 and flows off there to a coolant.
- the electrons passing through the target are braked and absorbed in the material of the electron absorber 7 located behind them. For this reason, in the beam direction behind the electron absorber 7 ordered filter plate 11 also no further X-rays are generated.
- a material has therefore been used for the filter plate 11, which has been selected solely on the basis of its absorption properties - the largest possible absorption factor in the range of low-energy X-ray quanta of 1 to 3 MeV and the smallest possible absorption factor in the range of higher-energy X-ray quanta above 3 MeV.
- the heavy metals lead, tantalum, gold, tungsten and uranium are particularly suitable for this purpose.
- a 2 mm thick filter plate made of lead was used for an electron energy of approx. 4 MeV. Since the filter plate 11 is equally strong over the entire maximum radiation cross section to be used, the hardening effect for the radiation is also uniform over this entire radiation cross section.
- the compensating body following in the beam direction needs and should therefore no longer show any hardening effect. It can therefore be made of a material with a low atomic number. be made, in which the absorption over the entire occurring X-ray energy spectrum is approximately the same size. Aluminum is particularly well suited for this.
- the advantage of this design can be seen in particular in the fact that the disadvantages with regard to the beam quality associated with the omission of the complex and bulky 270 ° deflection and focusing magnet for the electron beam 5 can largely be compensated for by the compensating body 15 made of a material with a low atomic number, e.g. B. aluminum, and a filter plate 11 is used behind the electron absorber 7, the X-ray quanta of lower energy preferably absorbed.
- the design is not only decidedly cheaper, it also leads to devices that are much smaller and easier to position in medical applications.
Landscapes
- Physics & Mathematics (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Engineering & Computer Science (AREA)
- General Engineering & Computer Science (AREA)
- High Energy & Nuclear Physics (AREA)
- Particle Accelerators (AREA)
- Radiation-Therapy Devices (AREA)
- Apparatus For Radiation Diagnosis (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE2926883A DE2926883A1 (de) | 1979-07-03 | 1979-07-03 | Elektronenbeschleuniger |
DE2926883 | 1979-07-03 |
Publications (3)
Publication Number | Publication Date |
---|---|
EP0021441A2 EP0021441A2 (de) | 1981-01-07 |
EP0021441A3 EP0021441A3 (en) | 1981-01-14 |
EP0021441B1 true EP0021441B1 (de) | 1985-04-17 |
Family
ID=6074828
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP80103661A Expired EP0021441B1 (de) | 1979-07-03 | 1980-06-27 | Elektronenbeschleuniger zur Röntgenstrahlentherapie |
Country Status (5)
Country | Link |
---|---|
US (1) | US4300055A (enrdf_load_stackoverflow) |
EP (1) | EP0021441B1 (enrdf_load_stackoverflow) |
JP (1) | JPS5614199A (enrdf_load_stackoverflow) |
CA (1) | CA1139022A (enrdf_load_stackoverflow) |
DE (2) | DE2926883A1 (enrdf_load_stackoverflow) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3138731A1 (de) * | 1981-09-29 | 1983-04-07 | Siemens AG, 1000 Berlin und 8000 München | Ueberwachungsanordnung fuer die beschleunigungsenergie eines elektronenbeschleunigers |
FR2558327B1 (fr) * | 1984-01-17 | 1986-04-25 | Cgr Mev | Accelerateur de particules multiregimes |
NL9000896A (nl) * | 1990-04-17 | 1991-11-18 | Philips Nv | Roentgenstraling absorberend filter. |
FR2728472B1 (fr) * | 1994-12-27 | 1997-03-28 | Ge Medical Syst Sa | Appareil de radiotherapie utilisant un accelerateur lineaire d'electrons a tres haute frequence et des moyens de protection hors champ utile |
AU7137500A (en) | 1999-07-21 | 2001-02-13 | Jmar Research, Inc. | High collection angle short wavelength radiation collimator and focusing optic |
WO2001007939A1 (en) * | 1999-07-21 | 2001-02-01 | Jmar Research, Inc. | Collimator and focusing optic |
RU2245588C2 (ru) * | 2003-02-14 | 2005-01-27 | Белугин Владимир Михайлович | Источник проникающего излучения |
CN1822239B (zh) * | 2005-02-17 | 2010-06-23 | Ge医疗系统环球技术有限公司 | 滤波器和x射线成像设备 |
US7483518B2 (en) * | 2006-09-12 | 2009-01-27 | Siemens Medical Solutions Usa, Inc. | Apparatus and method for rapidly switching the energy spectrum of diagnostic X-ray beams |
CN101303909B (zh) * | 2007-05-11 | 2013-03-27 | Ge医疗系统环球技术有限公司 | 滤波器单元,x射线管单元和x射线成像系统 |
FR2926924B1 (fr) * | 2008-01-25 | 2012-10-12 | Thales Sa | Source radiogene comprenant au moins une source d'electrons associee a un dispositif photoelectrique de commande |
CN101658429A (zh) * | 2008-08-29 | 2010-03-03 | Ge医疗系统环球技术有限公司 | X光散射线阻挡叶片的调节装置 |
CN101853710B (zh) * | 2009-03-31 | 2014-11-19 | Ge医疗系统环球技术有限公司 | 滤波器及利用该滤波器的x射线成像设备 |
US20140264065A1 (en) * | 2013-03-15 | 2014-09-18 | Varian Medical Systems, Inc. | Energy degrader for radiation therapy system |
GB201414393D0 (en) * | 2014-08-13 | 2014-09-24 | Nikon Metrology Nv | Z-ray beam collimator |
DE102018112054B4 (de) * | 2018-05-18 | 2023-02-09 | Yxlon International Gmbh | Röntgenröhre mit Kollimator und Kollimatorvorrichtung für geschlossene Röntgenröhre |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2533348A1 (de) * | 1974-12-18 | 1976-06-24 | Atomic Energy Of Canada Ltd | Aus einzelnen schichten aufgebautes target zur bremsstrahlungserzeugung |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1153324A (fr) * | 1955-05-18 | 1958-03-05 | Thomson Houston Comp Francaise | Cible pour microscope à rayons x |
CA1007767A (en) * | 1973-09-04 | 1977-03-29 | Machlett Laboratories | Broad aperture x-ray generator |
US4121109A (en) * | 1977-04-13 | 1978-10-17 | Applied Radiation Corporation | Electron accelerator with a target exposed to the electron beam |
CA1102018A (en) * | 1978-01-09 | 1981-05-26 | Philip Mchugh | Unitary self shielded, self filtered and flattened bremsstrahlung photon source assembly for radiotherapy use |
-
1979
- 1979-07-03 DE DE2926883A patent/DE2926883A1/de not_active Withdrawn
-
1980
- 1980-05-22 US US06/152,349 patent/US4300055A/en not_active Expired - Lifetime
- 1980-06-27 DE DE8080103661T patent/DE3070505D1/de not_active Expired
- 1980-06-27 EP EP80103661A patent/EP0021441B1/de not_active Expired
- 1980-07-02 CA CA000355217A patent/CA1139022A/en not_active Expired
- 1980-07-03 JP JP9119780A patent/JPS5614199A/ja active Granted
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2533348A1 (de) * | 1974-12-18 | 1976-06-24 | Atomic Energy Of Canada Ltd | Aus einzelnen schichten aufgebautes target zur bremsstrahlungserzeugung |
Non-Patent Citations (2)
Title |
---|
Electromedica Nr. 3. 1979 (Auslieferungsdatum 14.08.79 siehe Eingabe 76 vom 19.05.83), W.E. SCHIEGL "Mevatron - das neue Konzept" S. 124-126 * |
Radiology Nr. 115, Mai 1975, R.J. BOGE et al."Accessory Beam Flattering Filter for the Varian Clinac-4 Linear Accelerator" S. 475-477 * |
Also Published As
Publication number | Publication date |
---|---|
JPS5614199A (en) | 1981-02-10 |
EP0021441A3 (en) | 1981-01-14 |
DE3070505D1 (en) | 1985-05-23 |
DE2926883A1 (de) | 1981-01-22 |
US4300055A (en) | 1981-11-10 |
CA1139022A (en) | 1983-01-04 |
EP0021441A2 (de) | 1981-01-07 |
JPS6312280B2 (enrdf_load_stackoverflow) | 1988-03-18 |
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