EG24473A - A synthetic methodology for the reductive alkylation at the C-3 position of indoles - Google Patents
A synthetic methodology for the reductive alkylation at the C-3 position of indolesInfo
- Publication number
- EG24473A EG24473A EGNA2006000557A EG24473A EG 24473 A EG24473 A EG 24473A EG NA2006000557 A EGNA2006000557 A EG NA2006000557A EG 24473 A EG24473 A EG 24473A
- Authority
- EG
- Egypt
- Prior art keywords
- indoles
- reductive alkylation
- synthetic methodology
- methodology
- synthetic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/22—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an aralkyl radical attached to the ring nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Rheumatology (AREA)
- Immunology (AREA)
- Dermatology (AREA)
- Pain & Pain Management (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US52979703P | 2003-12-16 | 2003-12-16 | |
| PCT/US2004/041989 WO2005058820A1 (en) | 2003-12-16 | 2004-12-15 | A synthetic methodology for the reductive alkylation at the c-3 position of indoles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EG24473A true EG24473A (en) | 2009-08-03 |
Family
ID=34700047
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EGNA2006000557 EG24473A (en) | 2003-12-16 | 2006-06-14 | A synthetic methodology for the reductive alkylation at the C-3 position of indoles |
Country Status (26)
| Country | Link |
|---|---|
| US (2) | US7282594B2 (xx) |
| EP (1) | EP1697320B1 (xx) |
| JP (1) | JP5121232B2 (xx) |
| KR (2) | KR20120082477A (xx) |
| CN (1) | CN1914170B (xx) |
| AR (1) | AR046895A1 (xx) |
| AU (1) | AU2004299462B2 (xx) |
| BR (1) | BRPI0417769B8 (xx) |
| CA (1) | CA2549120C (xx) |
| CR (1) | CR8446A (xx) |
| EC (1) | ECSP066648A (xx) |
| EG (1) | EG24473A (xx) |
| GT (1) | GT200400266A (xx) |
| HN (1) | HN2004000536A (xx) |
| IL (1) | IL176147A (xx) |
| MX (1) | MXPA06006669A (xx) |
| NI (1) | NI200600132A (xx) |
| NO (1) | NO20062757L (xx) |
| PA (1) | PA8620101A1 (xx) |
| PE (1) | PE20051012A1 (xx) |
| RU (1) | RU2352560C2 (xx) |
| SG (1) | SG147487A1 (xx) |
| TW (1) | TW200526576A (xx) |
| UA (1) | UA84445C2 (xx) |
| WO (1) | WO2005058820A1 (xx) |
| ZA (1) | ZA200604966B (xx) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7713964B2 (en) | 2001-12-03 | 2010-05-11 | Wyeth Llc | Methods for treating asthmatic conditions |
| US7605156B2 (en) | 2001-12-03 | 2009-10-20 | Wyeth | Methods for the use of inhibitors of cytosolic phospholipase A2 |
| TW200510305A (en) * | 2003-07-25 | 2005-03-16 | Wyeth Corp | Process for the preparation of CPLA2 inhibitors |
| US7582771B2 (en) * | 2003-09-03 | 2009-09-01 | Wyeth | Process for the synthesis of cPLA2 inhibitors |
| US7342119B2 (en) * | 2003-09-30 | 2008-03-11 | Wyeth Holdings Corporation | Process for the synthesis of a CPLA2 inhibitor |
| AR053410A1 (es) * | 2004-08-19 | 2007-05-09 | Wyeth Corp | Proceso para la sintesis de indoles n-alquilados c-2, c-3 sustituidos. compuestos intermediarios |
| TW200718687A (en) | 2005-05-27 | 2007-05-16 | Wyeth Corp | Inhibitors of cytosolic phospholipase A2 |
| WO2008055148A2 (en) * | 2006-10-31 | 2008-05-08 | Wyeth | Semi-solid formulations of phospholipase enzyme inhibitors |
| AU2007313706A1 (en) * | 2006-10-31 | 2008-05-08 | Wyeth | Liquid formulations of phospholipase enzyme inhibitors |
| CN111087340B (zh) * | 2019-11-29 | 2021-12-07 | 上海应用技术大学 | 一种维拉佐酮中间体的制备方法 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9317764D0 (en) | 1993-08-26 | 1993-10-13 | Pfizer Ltd | Therapeutic compound |
| GB9609641D0 (en) * | 1996-05-09 | 1996-07-10 | Pfizer Ltd | Compounds useful in therapy |
| US7101875B2 (en) | 2001-12-03 | 2006-09-05 | Wyeth | Methods for treating arthritic disorders |
| US7713964B2 (en) | 2001-12-03 | 2010-05-11 | Wyeth Llc | Methods for treating asthmatic conditions |
| US7605156B2 (en) | 2001-12-03 | 2009-10-20 | Wyeth | Methods for the use of inhibitors of cytosolic phospholipase A2 |
| WO2003048122A2 (en) * | 2001-12-03 | 2003-06-12 | Wyeth | Inhibitors of cytosolic phospholipase a2 |
| US6984735B2 (en) | 2001-12-03 | 2006-01-10 | Wyeth | Process for making an aldehyde |
| US6635771B2 (en) | 2001-12-03 | 2003-10-21 | Wyeth | N-benzhydryl indole compounds |
| US6797708B2 (en) | 2001-12-03 | 2004-09-28 | Wyeth | Inhibitors of cytosolic phospholipase A2 |
| US20040182785A1 (en) * | 2002-10-23 | 2004-09-23 | Rigel Technology Corporation | Animal plasma process by precipitation |
| TW200510305A (en) * | 2003-07-25 | 2005-03-16 | Wyeth Corp | Process for the preparation of CPLA2 inhibitors |
| US7582771B2 (en) | 2003-09-03 | 2009-09-01 | Wyeth | Process for the synthesis of cPLA2 inhibitors |
| US7342119B2 (en) * | 2003-09-30 | 2008-03-11 | Wyeth Holdings Corporation | Process for the synthesis of a CPLA2 inhibitor |
| AR053410A1 (es) | 2004-08-19 | 2007-05-09 | Wyeth Corp | Proceso para la sintesis de indoles n-alquilados c-2, c-3 sustituidos. compuestos intermediarios |
| TW200718687A (en) | 2005-05-27 | 2007-05-16 | Wyeth Corp | Inhibitors of cytosolic phospholipase A2 |
-
2004
- 2004-12-05 HN HN2004000536A patent/HN2004000536A/es unknown
- 2004-12-10 PE PE2004001237A patent/PE20051012A1/es not_active Application Discontinuation
- 2004-12-14 GT GT200400266A patent/GT200400266A/es unknown
- 2004-12-15 CN CN2004800416736A patent/CN1914170B/zh active Active
- 2004-12-15 TW TW093138860A patent/TW200526576A/zh unknown
- 2004-12-15 AU AU2004299462A patent/AU2004299462B2/en not_active Ceased
- 2004-12-15 WO PCT/US2004/041989 patent/WO2005058820A1/en active Application Filing
- 2004-12-15 JP JP2006545820A patent/JP5121232B2/ja not_active Expired - Fee Related
- 2004-12-15 RU RU2006125447/04A patent/RU2352560C2/ru active
- 2004-12-15 BR BRPI0417769A patent/BRPI0417769B8/pt active IP Right Grant
- 2004-12-15 MX MXPA06006669A patent/MXPA06006669A/es active IP Right Grant
- 2004-12-15 PA PA20048620101A patent/PA8620101A1/es unknown
- 2004-12-15 CA CA2549120A patent/CA2549120C/en active Active
- 2004-12-15 UA UAA200607900A patent/UA84445C2/ru unknown
- 2004-12-15 EP EP04814200.4A patent/EP1697320B1/en active Active
- 2004-12-15 SG SG200808109-3A patent/SG147487A1/en unknown
- 2004-12-15 KR KR1020127016929A patent/KR20120082477A/ko not_active Application Discontinuation
- 2004-12-15 KR KR1020067014252A patent/KR101194592B1/ko active IP Right Grant
- 2004-12-15 NI NI200600132A patent/NI200600132A/es unknown
- 2004-12-15 AR ARP040104672A patent/AR046895A1/es unknown
- 2004-12-16 US US11/014,657 patent/US7282594B2/en active Active
-
2006
- 2006-06-06 IL IL176147A patent/IL176147A/en active IP Right Grant
- 2006-06-08 CR CR8446A patent/CR8446A/es not_active Application Discontinuation
- 2006-06-13 NO NO20062757A patent/NO20062757L/no not_active Application Discontinuation
- 2006-06-14 EG EGNA2006000557 patent/EG24473A/xx active
- 2006-06-15 ZA ZA2006/04966A patent/ZA200604966B/en unknown
- 2006-06-16 EC EC2006006648A patent/ECSP066648A/es unknown
-
2007
- 2007-10-15 US US11/872,193 patent/US7709661B2/en active Active
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EG24473A (en) | A synthetic methodology for the reductive alkylation at the C-3 position of indoles | |
| GB0509275D0 (en) | Synthetic receptor | |
| AU153030S (en) | Holder for showers | |
| PL379420A1 (pl) | Pochodne blokerów receptora angiotensyny II | |
| IL192426A0 (en) | Prokineticin 2 receptor antagonists | |
| AP2008004401A0 (en) | Histamine-3 receptor antagonists | |
| EP1585549A4 (en) | IMPROVED PEPTIDE COMPOUNDS FOR GASTRINF REPLACEMENT | |
| AU2003218372A8 (en) | Modified release minerals | |
| IL192424A0 (en) | Prokineticin 1 receptor antagonists | |
| EP1689389A4 (en) | Indole compounds | |
| GB2391882B (en) | Technique for deploying expandables | |
| IL172902A0 (en) | Sensor for alkylating agents | |
| GB0509276D0 (en) | Synthetic receptor | |
| SG131946A1 (en) | Ccr3 receptor antagonists | |
| IL175297A0 (en) | New coupling agents for peptide synthesis | |
| EP1633658A4 (en) | CONSUMABLE PACKAGING FOR TRANSPARENT BINDERS | |
| GB0525029D0 (en) | Receptor Antagonist | |
| GB0215389D0 (en) | Receptor | |
| TWI347183B (en) | 2-(1h-indolylsulfanyl)-benzyl amine derivatives | |
| TW569999U (en) | Positioning device for seat | |
| IL175785A0 (en) | Gastrin releasing peptide compounds | |
| GB0321998D0 (en) | Receptor | |
| GB2397748B (en) | Dispensers for bags | |
| GB0329104D0 (en) | Receptor | |
| GB0307100D0 (en) | Receptor |