EG15419A - Process for preparing azabicyclooctane-carboxylic acids - Google Patents

Process for preparing azabicyclooctane-carboxylic acids

Info

Publication number
EG15419A
EG15419A EG81609A EG60981A EG15419A EG 15419 A EG15419 A EG 15419A EG 81609 A EG81609 A EG 81609A EG 60981 A EG60981 A EG 60981A EG 15419 A EG15419 A EG 15419A
Authority
EG
Egypt
Prior art keywords
azabicyclooctane
preparing
carboxylic acids
carboxylic
acids
Prior art date
Application number
EG81609A
Other languages
English (en)
Original Assignee
Adir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adir filed Critical Adir
Application granted granted Critical
Publication of EG15419A publication Critical patent/EG15419A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/32—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems containing carbocyclic rings other than six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/06—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing isoquinuclidine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
EG81609A 1980-10-21 1981-10-20 Process for preparing azabicyclooctane-carboxylic acids EG15419A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8022438A FR2492381A1 (fr) 1980-10-21 1980-10-21 Nouveaux acides aza bicyclo alcane carboxyliques substitues leurs procedes de preparation et leur emploi comme inhibiteur d'enzyme

Publications (1)

Publication Number Publication Date
EG15419A true EG15419A (en) 1986-03-31

Family

ID=9247120

Family Applications (1)

Application Number Title Priority Date Filing Date
EG81609A EG15419A (en) 1980-10-21 1981-10-20 Process for preparing azabicyclooctane-carboxylic acids

Country Status (29)

Country Link
US (1) US4397857A (es)
EP (1) EP0051020B1 (es)
JP (2) JPS5798281A (es)
KR (1) KR860001877B1 (es)
AR (1) AR228621A1 (es)
AT (1) ATE8892T1 (es)
AU (1) AU540609B2 (es)
CA (1) CA1183140A (es)
DD (1) DD201891A5 (es)
DE (1) DE3165428D1 (es)
DK (1) DK162444C (es)
EG (1) EG15419A (es)
ES (1) ES8301927A1 (es)
FI (1) FI73678C (es)
FR (2) FR2492381A1 (es)
GR (1) GR75389B (es)
HU (1) HU185058B (es)
IE (1) IE51823B1 (es)
IL (1) IL64075A0 (es)
MA (1) MA19307A1 (es)
MX (1) MX155032A (es)
NO (1) NO155098C (es)
NZ (1) NZ198701A (es)
OA (1) OA06930A (es)
PH (1) PH17338A (es)
PT (1) PT73857B (es)
SU (1) SU1138022A3 (es)
YU (1) YU42587B (es)
ZA (1) ZA817251B (es)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3174844D1 (en) * 1980-10-23 1986-07-24 Schering Corp Carboxyalkyl dipeptides, processes for their production and pharmaceutical compositions containing them
IE54551B1 (en) * 1982-01-22 1989-11-22 Ici Plc Amide derivatives
DE3227055A1 (de) * 1982-07-20 1984-01-26 Hoechst Ag, 6230 Frankfurt Neue derivate der 2-aza-bicyclo(2.2.2)octan-3-carbonsaeure, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung sowie 2-aza-bicyclo(2.2.2)octan-3-carbonsaeure als zwischenstufe und verfahren zu deren herstellung
DE3246757A1 (de) * 1982-12-17 1984-06-20 Hoechst Ag, 6230 Frankfurt Neue 2-azabicyclo(2.2.1)heptan-derivate, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung sowie 2-azabicyclo(2.2.1)heptan-derivate als zwischenprodukte und verfahren zu deren herstellung
DE3303344A1 (de) 1983-02-02 1984-08-02 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von n-alkylierten aminosaeuren und deren estern
US4693996A (en) * 1985-12-23 1987-09-15 Warner-Lambert Company Method of treating heart failure and medicaments therefor
DE3707911C1 (de) * 1987-03-12 1988-03-31 Texaco Ag Bicyclische Aminkatalysatoren
FR2619813B1 (fr) * 1987-08-28 1991-05-03 Adir Nouveaux derives de l'acide aza - 2 bicyclooctane carboxylique - 3, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent
FR2635684A1 (fr) * 1988-08-24 1990-03-02 Adir Utilisation de derives de l'acide aza - 2 bicyclooctane (2.2.2) carboxylique - 3 pour l'obtention de medicaments destines au traitement des maladies consecutives a l'alteration de la paroi vasculaire ainsi qu'aux troubles de la microcirculation
JPH0426348U (es) * 1990-06-25 1992-03-02
TW197945B (es) * 1990-11-27 1993-01-11 Hoechst Ag
LT3872B (en) 1993-12-06 1996-04-25 Hoechst Ag Novel peptides and pharmaceutical compositions containing them
FR2746394B1 (fr) 1996-03-20 1998-05-29 Roussel Uclaf Nouveaux composes tricycliques, leur procede de preparation, et les intermediaires de ce procede, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant
DE59706273D1 (de) 1996-03-20 2002-03-21 Hoechst Ag Inhibitoren der Knochenresorption und Vitronectinrezeptor-Antagonisten
DE19653647A1 (de) 1996-12-20 1998-06-25 Hoechst Ag Vitronectin - Rezeptorantagonisten, deren Herstellung sowie deren Verwendung
DE19821483A1 (de) 1998-05-14 1999-11-18 Hoechst Marion Roussel De Gmbh Imidazolidinderivate, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate
MXPA02012605A (es) * 2000-06-28 2003-05-14 Squibb Bristol Myers Co Moduladores selectivos del receptor androgeno y metodo para su identificacion, dise°o y uso.
US7001911B2 (en) 2000-06-28 2006-02-21 Bristol-Myers Squibb Company Fused cyclic modulators of nuclear hormone receptor function
US20040077605A1 (en) 2001-06-20 2004-04-22 Salvati Mark E. Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
US6953679B2 (en) 2000-09-19 2005-10-11 Bristol-Myers Squibb Company Method for the preparation of fused heterocyclic succinimide compounds and analogs thereof
EP1854798A3 (en) * 2000-09-19 2007-11-28 Bristol-Myers Squibb Company Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
US20040087548A1 (en) 2001-02-27 2004-05-06 Salvati Mark E. Fused cyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
ES2310622T3 (es) * 2001-12-19 2009-01-16 Bristol-Myers Squibb Company Compuestos heterociclicos condensados y analogos de los mismos, moduladores de la funcion de los receptores nucleares de hormonas.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE94175C (es) *
GB1095105A (en) * 1965-04-12 1967-12-13 Scherico Ltd Novel n-(phenyl-sulfonyl)-isoquinuclidine-carboxamides
US3741973A (en) * 1967-09-11 1973-06-26 Upjohn Co Oxygenated 3-azabicyclo(3.3.1)nonanes
IE52663B1 (en) * 1980-04-02 1988-01-20 Warner Lambert Co Substituted acyl derivatives of octahydro-1h-indole-2-carboxylic acids

Also Published As

Publication number Publication date
IL64075A0 (en) 1982-01-31
ZA817251B (en) 1982-09-29
KR860001877B1 (ko) 1986-10-24
CA1183140A (fr) 1985-02-26
FR2525604B2 (fr) 1985-06-07
JPS5798281A (en) 1982-06-18
ATE8892T1 (de) 1984-08-15
FR2525604A2 (fr) 1983-10-28
DD201891A5 (de) 1983-08-17
SU1138022A3 (ru) 1985-01-30
GR75389B (es) 1984-07-13
PT73857A (fr) 1981-11-01
PT73857B (fr) 1983-01-25
KR830007570A (ko) 1983-10-21
FI73678C (fi) 1987-11-09
US4397857A (en) 1983-08-09
HU185058B (en) 1984-11-28
DK162444B (da) 1991-10-28
IE812460L (en) 1982-04-21
JPS6146453B2 (es) 1986-10-14
ES506222A0 (es) 1983-01-01
YU245481A (en) 1984-04-30
AU540609B2 (en) 1984-11-29
MA19307A1 (fr) 1982-07-01
YU42587B (en) 1988-10-31
NO813541L (no) 1982-04-22
IE51823B1 (en) 1987-04-01
NO155098B (no) 1986-11-03
DK460181A (da) 1982-04-22
EP0051020A1 (fr) 1982-05-05
DK162444C (da) 1992-03-23
PH17338A (en) 1984-08-01
MX155032A (es) 1988-01-21
FR2492381B1 (es) 1983-08-12
ES8301927A1 (es) 1983-01-01
NZ198701A (en) 1984-07-06
NO155098C (no) 1987-02-11
DE3165428D1 (en) 1984-09-13
FI813279L (fi) 1982-04-22
EP0051020B1 (fr) 1984-08-08
FI73678B (fi) 1987-07-31
OA06930A (fr) 1983-05-31
AU7662481A (en) 1982-04-29
FR2492381A1 (fr) 1982-04-23
JPS61126025A (ja) 1986-06-13
JPS6112911B2 (es) 1986-04-10
AR228621A1 (es) 1983-03-30

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