EE9600197A - Uudsed 1,1-bis(heteroasolüül)alkaani derivaadid ja nende kasutamine neuroprotektiivsete ainetena - Google Patents

Uudsed 1,1-bis(heteroasolüül)alkaani derivaadid ja nende kasutamine neuroprotektiivsete ainetena

Info

Publication number
EE9600197A
EE9600197A EE9600197A EE9600197A EE9600197A EE 9600197 A EE9600197 A EE 9600197A EE 9600197 A EE9600197 A EE 9600197A EE 9600197 A EE9600197 A EE 9600197A EE 9600197 A EE9600197 A EE 9600197A
Authority
EE
Estonia
Prior art keywords
heteroazolyl
bis
novel
neuroprotective agents
alkane derivatives
Prior art date
Application number
EE9600197A
Other languages
English (en)
Inventor
Robin Boar Bernard
Alastair Gray Duncan
Mark O'shea Dennis
Original Assignee
Astra Aktiebolag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Aktiebolag filed Critical Astra Aktiebolag
Publication of EE9600197A publication Critical patent/EE9600197A/et

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/32Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/427Thiazoles not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/24Radicals substituted by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/28Radicals substituted by nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
EE9600197A 1994-06-07 1995-05-29 Uudsed 1,1-bis(heteroasolüül)alkaani derivaadid ja nende kasutamine neuroprotektiivsete ainetena EE9600197A (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9401965A SE9401965D0 (sv) 1994-06-07 1994-06-07 New compounds
PCT/SE1995/000604 WO1995033747A1 (en) 1994-06-07 1995-05-29 Novel 1,1-bis(heteroazolyl)alkane derivatives and their use as neuroprotective agents

Publications (1)

Publication Number Publication Date
EE9600197A true EE9600197A (et) 1997-06-16

Family

ID=20394274

Family Applications (1)

Application Number Title Priority Date Filing Date
EE9600197A EE9600197A (et) 1994-06-07 1995-05-29 Uudsed 1,1-bis(heteroasolüül)alkaani derivaadid ja nende kasutamine neuroprotektiivsete ainetena

Country Status (26)

Country Link
US (2) US5843971A (et)
EP (1) EP0765325A1 (et)
JP (1) JPH10503172A (et)
CN (1) CN1051546C (et)
AU (1) AU691303B2 (et)
BR (1) BR9507923A (et)
CA (1) CA2190128A1 (et)
CZ (1) CZ357796A3 (et)
DZ (1) DZ1895A1 (et)
EE (1) EE9600197A (et)
FI (1) FI964879A (et)
HR (1) HRP950302A2 (et)
HU (1) HUT76050A (et)
IL (1) IL113773A (et)
IS (1) IS4383A (et)
MA (1) MA23574A1 (et)
NO (1) NO307421B1 (et)
NZ (1) NZ287973A (et)
PL (1) PL318470A1 (et)
RU (1) RU2155763C2 (et)
SE (1) SE9401965D0 (et)
SK (1) SK155696A3 (et)
TN (1) TNSN95065A1 (et)
WO (1) WO1995033747A1 (et)
YU (1) YU38695A (et)
ZA (1) ZA954145B (et)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9401965D0 (sv) * 1994-06-07 1994-06-07 Astra Ab New compounds
US6921538B2 (en) * 2002-05-10 2005-07-26 Allergan, Inc. Therapeutic treatments for neuropsychiatric disorders
US7649098B2 (en) * 2006-02-24 2010-01-19 Lexicon Pharmaceuticals, Inc. Imidazole-based compounds, compositions comprising them and methods of their use
TW200920355A (en) * 2007-09-06 2009-05-16 Lexicon Pharmaceuticals Inc Compositions and methods for treating immunological and inflammatory diseases and disorders

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2801794A1 (de) * 1978-01-17 1979-07-19 Basf Ag Verfahren zur herstellung von thiazolderivaten und neue thiazole
US5554620A (en) * 1993-09-14 1996-09-10 Sterling Winthrop Inc. Substituted 6,11-ethano-6,11-dihydrobenzo[b] quinolizinium salts and compositions and methods of use thereof
SE9401965D0 (sv) * 1994-06-07 1994-06-07 Astra Ab New compounds

Also Published As

Publication number Publication date
YU38695A (sh) 1998-12-23
HUT76050A (en) 1997-06-30
CN1150426A (zh) 1997-05-21
MA23574A1 (fr) 1995-12-31
DZ1895A1 (fr) 2002-02-17
US5665747A (en) 1997-09-09
EP0765325A1 (en) 1997-04-02
SK155696A3 (en) 1997-05-07
IL113773A0 (en) 1995-08-31
US5843971A (en) 1998-12-01
CN1051546C (zh) 2000-04-19
IS4383A (is) 1996-11-12
RU2155763C2 (ru) 2000-09-10
NO307421B1 (no) 2000-04-03
ZA954145B (en) 1995-12-07
AU691303B2 (en) 1998-05-14
AU2685995A (en) 1996-01-04
TNSN95065A1 (fr) 1996-02-06
NZ287973A (en) 1998-04-27
CA2190128A1 (en) 1995-12-14
NO965182D0 (no) 1996-12-04
FI964879A0 (fi) 1996-12-05
HU9603386D0 (en) 1997-01-28
IL113773A (en) 2000-02-29
BR9507923A (pt) 1997-09-23
FI964879A (fi) 1996-12-05
NO965182L (no) 1996-12-04
PL318470A1 (en) 1997-06-23
SE9401965D0 (sv) 1994-06-07
JPH10503172A (ja) 1998-03-24
WO1995033747A1 (en) 1995-12-14
CZ357796A3 (en) 1997-06-11
HRP950302A2 (en) 1997-08-31

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