ECSP22076862A - Compuestos antivirales y métodos para la administración de los mismos - Google Patents
Compuestos antivirales y métodos para la administración de los mismosInfo
- Publication number
- ECSP22076862A ECSP22076862A ECSENADI202276862A ECDI202276862A ECSP22076862A EC SP22076862 A ECSP22076862 A EC SP22076862A EC SENADI202276862 A ECSENADI202276862 A EC SENADI202276862A EC DI202276862 A ECDI202276862 A EC DI202276862A EC SP22076862 A ECSP22076862 A EC SP22076862A
- Authority
- EC
- Ecuador
- Prior art keywords
- administration
- methods
- covid
- antiviral
- antiviral compounds
- Prior art date
Links
- 230000000840 anti-viral effect Effects 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 208000025721 COVID-19 Diseases 0.000 abstract 2
- 239000003443 antiviral agent Substances 0.000 abstract 2
- 241001678559 COVID-19 virus Species 0.000 abstract 1
- 208000036142 Viral infection Diseases 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 230000007246 mechanism Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000002685 pulmonary effect Effects 0.000 abstract 1
- 230000009385 viral infection Effects 0.000 abstract 1
- 230000003612 virological effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/55—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound the modifying agent being also a pharmacologically or therapeutically active agent, i.e. the entire conjugate being a codrug, i.e. a dimer, oligomer or polymer of pharmacologically or therapeutically active compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4706—4-Aminoquinolines; 8-Aminoquinolines, e.g. chloroquine, primaquine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Oncology (AREA)
- Virology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Abstract
Esta invención se relaciona con el uso de medicamentos antivirales con diferentes mecanismos de acción para tratar o prevenir infecciones virales como la COVID-19 (también conocida como SARS-CoV-2) y reducir las complicaciones médicas relacionadas con la enfermedad viral de la COVID-19. La presente invención también se refiere a composiciones y combinaciones de nuevos fármacos antivirales formados a partir de fármacos existentes con actividad antiviral, y la administración de estos compuestos usados en estas diversas combinaciones nuevas, que se incorporan en sistemas de administración pulmonar y oral.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US202062993121P | 2020-03-23 | 2020-03-23 |
Publications (1)
Publication Number | Publication Date |
---|---|
ECSP22076862A true ECSP22076862A (es) | 2022-11-30 |
Family
ID=77890599
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ECSENADI202276862A ECSP22076862A (es) | 2020-03-23 | 2022-09-30 | Compuestos antivirales y métodos para la administración de los mismos |
Country Status (18)
Country | Link |
---|---|
US (2) | US20230263778A1 (es) |
EP (1) | EP4110330A4 (es) |
JP (1) | JP2023519158A (es) |
KR (1) | KR20220158242A (es) |
CN (1) | CN115697328A (es) |
AU (1) | AU2021244718A1 (es) |
BR (1) | BR112022018236A2 (es) |
CA (1) | CA3170367A1 (es) |
CL (1) | CL2022002481A1 (es) |
CO (1) | CO2022014073A2 (es) |
CR (1) | CR20220491A (es) |
DO (1) | DOP2022000185A (es) |
EC (1) | ECSP22076862A (es) |
IL (1) | IL296152A (es) |
MX (1) | MX2022011370A (es) |
PE (1) | PE20221868A1 (es) |
WO (1) | WO2021195661A1 (es) |
ZA (1) | ZA202211060B (es) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA3163424A1 (en) | 2020-01-27 | 2021-08-05 | Gilead Sciences, Inc. | Methods for treating sars cov-2 infections |
JP7554841B2 (ja) | 2020-03-12 | 2024-09-20 | ギリアード サイエンシーズ, インコーポレイテッド | 1’-シアノヌクレオシドを調製する方法 |
US11701372B2 (en) | 2020-04-06 | 2023-07-18 | Gilead Sciences, Inc. | Inhalation formulations of 1'-cyano substituted carba-nucleoside analogs |
KR20230018473A (ko) | 2020-05-29 | 2023-02-07 | 길리애드 사이언시즈, 인코포레이티드 | 렘데시비르 치료 방법 |
CN115996928A (zh) | 2020-06-24 | 2023-04-21 | 吉利德科学公司 | 1’-氰基核苷类似物及其用途 |
AU2021331214B2 (en) | 2020-08-27 | 2024-01-04 | Gilead Sciences, Inc. | Compounds and methods for treatment of viral infections |
WO2023075714A1 (en) * | 2021-10-25 | 2023-05-04 | Arven Ilac Sanayi Ve Ticaret Anonim Sirketi | Dry powder compositions comprising anti-viral agents |
IT202100029909A1 (it) * | 2021-11-26 | 2023-05-26 | Craniomed Group S R L | Combinazione di uno o più antibiotici della classe delle ansamicine con uno o più altri antibiotici per la prevenzione e il trattamento di infezioni causate da coronavirus, delle relative malattie e degli effetti clinici indotti dalle tossine prodotte a seguito dell’infezione da coronavirus. |
TW202400185A (zh) | 2022-03-02 | 2024-01-01 | 美商基利科學股份有限公司 | 用於治療病毒感染的化合物及方法 |
CN114568490B (zh) * | 2022-04-01 | 2023-12-19 | 眉山职业技术学院(眉山技师学院) | 雷帕霉素在抑制柑橘青霉菌生长中的应用 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040115268A1 (en) * | 2000-04-26 | 2004-06-17 | Control Delivery Systems, Inc. | Systemic delivery of antiviral agents |
US20050164994A1 (en) * | 2001-12-10 | 2005-07-28 | Control Deliver Systems, Inc. | Treatment of genitourinary tract disorders |
TW200500067A (en) * | 2003-01-21 | 2005-01-01 | Control Delivery Sys Inc | Salts of codrugs and uses related thereto |
WO2005113580A1 (en) * | 2004-05-21 | 2005-12-01 | Pfizer Inc. | Anticoronviral compounds and compositions, their pharmaceutical uses and materials for their synthesis |
CN101039701A (zh) * | 2004-08-26 | 2007-09-19 | 尼古拉斯皮拉马尔印度有限公司 | 含有生物可裂解二硫化物连接物的前药和共药 |
TW200719916A (en) * | 2005-04-12 | 2007-06-01 | Psivida Inc | HMGCoA reductase inhibitor combinations and uses thereof |
WO2007016306A2 (en) * | 2005-08-01 | 2007-02-08 | Psivida Inc. | HMGCoA REDUCTASE INHIBITOR CODRUGS AND USES THEREOF |
WO2008094507A2 (en) * | 2007-01-26 | 2008-08-07 | Cellicon Biotechnologies, Inc. | Novel fusion compounds |
US20170044096A1 (en) * | 2013-03-15 | 2017-02-16 | Rutgers, The State University Of New Jersey | Augmenting Moieties for Anti-Inflammatory Compounds |
WO2012138911A2 (en) * | 2011-04-05 | 2012-10-11 | The Administrators Of The Tulane Educational Fund | Conjugates of anti-hiv drugs and somatostatin analogs |
US20230157998A1 (en) * | 2020-03-06 | 2023-05-25 | Pfizer Inc. | Methods of Inhibiting SARS-CoV-2 Replication and Treating Corona Virus Disease 2019 |
CN111450088B (zh) * | 2020-04-30 | 2021-08-03 | 上海爱启医药技术有限公司 | 二杨梅素基二硒醚的药物应用 |
-
2021
- 2021-03-23 PE PE2022001963A patent/PE20221868A1/es unknown
- 2021-03-23 US US17/905,601 patent/US20230263778A1/en active Pending
- 2021-03-23 MX MX2022011370A patent/MX2022011370A/es unknown
- 2021-03-23 BR BR112022018236A patent/BR112022018236A2/pt unknown
- 2021-03-23 CN CN202180021244.6A patent/CN115697328A/zh active Pending
- 2021-03-23 CA CA3170367A patent/CA3170367A1/en active Pending
- 2021-03-23 EP EP21775547.9A patent/EP4110330A4/en active Pending
- 2021-03-23 IL IL296152A patent/IL296152A/en unknown
- 2021-03-23 WO PCT/US2021/070300 patent/WO2021195661A1/en active Application Filing
- 2021-03-23 JP JP2022553649A patent/JP2023519158A/ja active Pending
- 2021-03-23 AU AU2021244718A patent/AU2021244718A1/en active Pending
- 2021-03-23 KR KR1020227035247A patent/KR20220158242A/ko active Search and Examination
- 2021-03-23 CR CR20220491A patent/CR20220491A/es unknown
-
2022
- 2022-09-12 CL CL2022002481A patent/CL2022002481A1/es unknown
- 2022-09-13 DO DO2022000185A patent/DOP2022000185A/es unknown
- 2022-09-30 CO CONC2022/0014073A patent/CO2022014073A2/es unknown
- 2022-09-30 EC ECSENADI202276862A patent/ECSP22076862A/es unknown
- 2022-10-10 ZA ZA2022/11060A patent/ZA202211060B/en unknown
- 2022-10-25 US US18/049,508 patent/US20230201167A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
BR112022018236A2 (pt) | 2022-10-25 |
MX2022011370A (es) | 2022-10-07 |
IL296152A (en) | 2022-11-01 |
KR20220158242A (ko) | 2022-11-30 |
US20230201167A1 (en) | 2023-06-29 |
DOP2022000185A (es) | 2023-01-31 |
JP2023519158A (ja) | 2023-05-10 |
WO2021195661A1 (en) | 2021-09-30 |
CR20220491A (es) | 2022-12-12 |
EP4110330A4 (en) | 2024-04-03 |
AU2021244718A1 (en) | 2022-11-03 |
CO2022014073A2 (es) | 2022-10-31 |
EP4110330A1 (en) | 2023-01-04 |
CA3170367A1 (en) | 2021-09-30 |
ZA202211060B (en) | 2023-12-20 |
CL2022002481A1 (es) | 2023-02-10 |
PE20221868A1 (es) | 2022-12-02 |
US20230263778A1 (en) | 2023-08-24 |
CN115697328A (zh) | 2023-02-03 |
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