ECSP19081839A - Método para preparar intermedio de derivado de 4-metoxipirrol - Google Patents

Método para preparar intermedio de derivado de 4-metoxipirrol

Info

Publication number
ECSP19081839A
ECSP19081839A ECSENADI201981839A ECDI201981839A ECSP19081839A EC SP19081839 A ECSP19081839 A EC SP19081839A EC SENADI201981839 A ECSENADI201981839 A EC SENADI201981839A EC DI201981839 A ECDI201981839 A EC DI201981839A EC SP19081839 A ECSP19081839 A EC SP19081839A
Authority
EC
Ecuador
Prior art keywords
preparing
metoxypirrol
derivative intermediate
methoxypyrrole
derivatives
Prior art date
Application number
ECSENADI201981839A
Other languages
English (en)
Inventor
Jeong-Taek Shin
Chun Ho Lee
Deok Ki Eom
Jeong Hyun Son
Original Assignee
Dae Woong Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dae Woong Pharma filed Critical Dae Woong Pharma
Publication of ECSP19081839A publication Critical patent/ECSP19081839A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/36—Oxygen or sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4015—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La presente invención se refiere a un método para preparar productos intermedios de derivados de 4-metoxipirrol. El método de preparación según la presente invención tiene las ventajas de que no se requiere una elevada temperatura de reacción en su totalidad, se usan reactivos económicos y no explosivos en lugar de (trimetilsilil)diazometano, y puede prepararse además un producto intermedio de derivados de 4-metoxipirrol en su totalidad a un alto rendimiento.
ECSENADI201981839A 2017-05-31 2019-11-15 Método para preparar intermedio de derivado de 4-metoxipirrol ECSP19081839A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1020170067646A KR102233456B1 (ko) 2017-05-31 2017-05-31 4-메톡시피롤 유도체의 중간체 제조 방법

Publications (1)

Publication Number Publication Date
ECSP19081839A true ECSP19081839A (es) 2019-11-30

Family

ID=64456008

Family Applications (1)

Application Number Title Priority Date Filing Date
ECSENADI201981839A ECSP19081839A (es) 2017-05-31 2019-11-15 Método para preparar intermedio de derivado de 4-metoxipirrol

Country Status (23)

Country Link
US (1) US10710961B2 (es)
EP (2) EP4219448A1 (es)
JP (1) JP6799177B2 (es)
KR (1) KR102233456B1 (es)
CN (1) CN110637009B (es)
AU (1) AU2018278731B2 (es)
BR (1) BR112019024976A2 (es)
CA (1) CA3061708C (es)
CL (1) CL2019003449A1 (es)
CO (1) CO2019012686A2 (es)
DO (1) DOP2019000292A (es)
EC (1) ECSP19081839A (es)
JO (1) JOP20190264A1 (es)
MA (1) MA50517A (es)
MX (1) MX2019014323A (es)
MY (1) MY193162A (es)
NZ (1) NZ758743A (es)
PE (1) PE20200399A1 (es)
PH (1) PH12019502638A1 (es)
RU (1) RU2718920C1 (es)
SA (1) SA519410408B1 (es)
TN (1) TN2019000300A1 (es)
WO (1) WO2018221971A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102081920B1 (ko) 2016-03-25 2020-02-26 주식회사 대웅제약 1-(5-(2,4-다이플루오로페닐)-1-((3-플루오로페닐)술포닐)-4-메톡시-1h-피롤-3-일)-n-메틸메탄아민 염의 신규한 결정형
KR102233455B1 (ko) 2017-06-21 2021-03-29 주식회사 대웅제약 4-메톡시피롤 유도체의 중간체 제조 방법
WO2022051979A1 (zh) * 2020-09-10 2022-03-17 广东莱佛士制药技术有限公司 一种制备钾离子竞争性阻滞剂中间体的方法
CN112094219B (zh) * 2020-09-10 2022-08-05 广东莱佛士制药技术有限公司 一种制备钾离子竞争性阻滞剂中间体的方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5622948A (en) 1994-12-01 1997-04-22 Syntex (U.S.A.) Inc. Pyrrole pyridazine and pyridazinone anti-inflammatory agents
KR100286874B1 (ko) * 1998-03-04 2001-04-16 성재갑 보호된 4-아미노메틸-피롤리딘-3-온의 제조방법
KR100958829B1 (ko) * 2004-09-03 2010-05-25 주식회사유한양행 피롤로[2,3-ｃ]피리딘 유도체 및 그의 제조방법
US8048909B2 (en) 2004-09-30 2011-11-01 Takeda Pharmaceutical Company Limited Proton pump inhibitors
DE102004053191A1 (de) * 2004-11-04 2006-05-11 Bayer Cropscience Ag 2,6-Diethyl-4-methyl-phenyl substituierte Tetramsäure-Derivate
EP1963311B1 (en) * 2005-12-19 2010-06-16 RaQualia Pharma Inc Chromane substituted benzimidazoles and their use as acid pump inhibitors
CA2891523A1 (en) 2012-11-19 2014-05-22 Jiangsu Hansoh Pharmaceutical Co., Ltd. Pyrrole sulfonamide derivative, preparation method for same, and medical application thereof
KR101613245B1 (ko) 2015-04-27 2016-04-18 주식회사 대웅제약 신규의 4-메톡시 피롤 유도체 또는 이의 염 및 이를 포함하는 약학 조성물
KR102081920B1 (ko) * 2016-03-25 2020-02-26 주식회사 대웅제약 1-(5-(2,4-다이플루오로페닐)-1-((3-플루오로페닐)술포닐)-4-메톡시-1h-피롤-3-일)-n-메틸메탄아민 염의 신규한 결정형

Also Published As

Publication number Publication date
JP6799177B2 (ja) 2020-12-09
BR112019024976A2 (pt) 2020-06-23
CL2019003449A1 (es) 2020-03-27
TN2019000300A1 (en) 2021-05-07
EP3630722A4 (en) 2020-10-21
NZ758743A (en) 2022-07-29
DOP2019000292A (es) 2019-12-15
AU2018278731B2 (en) 2021-02-18
CA3061708C (en) 2021-06-22
PH12019502638A1 (en) 2020-07-13
KR20180131081A (ko) 2018-12-10
JOP20190264A1 (ar) 2019-11-12
CA3061708A1 (en) 2018-12-06
PE20200399A1 (es) 2020-02-26
MY193162A (en) 2022-09-26
AU2018278731A1 (en) 2019-11-21
CN110637009A (zh) 2019-12-31
US10710961B2 (en) 2020-07-14
RU2718920C1 (ru) 2020-04-15
WO2018221971A1 (en) 2018-12-06
EP3630722A1 (en) 2020-04-08
EP4219448A1 (en) 2023-08-02
KR102233456B1 (ko) 2021-03-29
MA50517A (fr) 2020-09-09
CO2019012686A2 (es) 2020-04-01
JP2020518647A (ja) 2020-06-25
MX2019014323A (es) 2020-02-10
SA519410408B1 (ar) 2021-10-21
CN110637009B (zh) 2023-11-10
US20200181079A1 (en) 2020-06-11

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