ECSP055803A - Ésteres de ácido carbámico con actividad anticolinérgica - Google Patents

Ésteres de ácido carbámico con actividad anticolinérgica

Info

Publication number
ECSP055803A
ECSP055803A EC2005005803A ECSP055803A ECSP055803A EC SP055803 A ECSP055803 A EC SP055803A EC 2005005803 A EC2005005803 A EC 2005005803A EC SP055803 A ECSP055803 A EC SP055803A EC SP055803 A ECSP055803 A EC SP055803A
Authority
EC
Ecuador
Prior art keywords
esters
carbamic acid
anticolinergical
activity
relates
Prior art date
Application number
EC2005005803A
Other languages
English (en)
Inventor
Matthias Hoffmann
Michael Pieper
Georg Speck
Matthias Grauert
Steffen Breitfelder
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Publication of ECSP055803A publication Critical patent/ECSP055803A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Reproductive Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

La presente invención se refiere a nuevos ésteres del ácido carbámico de la fórmula general 1 1en la que X- y los grupos A, R1, R2, R3 y R4 pueden tener los significados mencionados en las reivindicaciones y en la descripción, a procedimientos para su preparación, así como a su uso como medicamentos, en especial como medicamentos con actividad anticolinérgica
EC2005005803A 2002-11-26 2005-05-19 Ésteres de ácido carbámico con actividad anticolinérgica ECSP055803A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10255040A DE10255040A1 (de) 2002-11-26 2002-11-26 Neue Carbaminsäureester mit anticholinerger Wirksamkeit

Publications (1)

Publication Number Publication Date
ECSP055803A true ECSP055803A (es) 2005-08-11

Family

ID=32240420

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2005005803A ECSP055803A (es) 2002-11-26 2005-05-19 Ésteres de ácido carbámico con actividad anticolinérgica

Country Status (20)

Country Link
EP (1) EP1567526B1 (es)
JP (1) JP4754829B2 (es)
KR (1) KR20050086821A (es)
CN (1) CN1717408A (es)
AT (1) ATE392424T1 (es)
AU (1) AU2003289880A1 (es)
BR (1) BR0316549A (es)
CA (1) CA2507110C (es)
DE (2) DE10255040A1 (es)
EA (1) EA200500775A1 (es)
EC (1) ECSP055803A (es)
ES (1) ES2304538T3 (es)
HR (1) HRP20050465A2 (es)
MX (1) MXPA05005443A (es)
NO (1) NO20053089D0 (es)
PL (1) PL376638A1 (es)
RS (1) RS20050384A (es)
UA (1) UA81649C2 (es)
WO (1) WO2004048373A1 (es)
ZA (1) ZA200502946B (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1626970B1 (en) * 2003-05-28 2009-07-08 Theravance, Inc. Azabicycloalkane compounds as muscarinic receptor antagonists
TW200534855A (en) * 2004-01-13 2005-11-01 Glaxo Group Ltd Muscarinic acetylcholine receptor antagonists
WO2006005057A2 (en) * 2004-06-30 2006-01-12 Glaxo Group Limited Muscarinic acetylcholine receptor antagonists
WO2006055503A2 (en) * 2004-11-15 2006-05-26 Glaxo Group Limited Novel m3 muscarinic acetylcholine receptor antagonists
WO2007007282A2 (en) * 2005-07-11 2007-01-18 Ranbaxy Laboratories Limited Azabicyclo derivatives as muscarinic receptor antagonists
JP2009519310A (ja) * 2005-12-16 2009-05-14 アージェンタ ディスカバリー リミテッド 環状アミン誘導体およびそれらの使用
CN101605784B (zh) 2007-02-09 2013-04-10 安斯泰来制药株式会社 氮杂桥环化合物
CN114732910A (zh) 2017-10-05 2022-07-12 弗尔康医疗公司 P38激酶抑制剂降低dux4和下游基因表达以用于治疗fshd
US10342786B2 (en) 2017-10-05 2019-07-09 Fulcrum Therapeutics, Inc. P38 kinase inhibitors reduce DUX4 and downstream gene expression for the treatment of FSHD
EP3710483A4 (en) 2017-11-16 2021-10-20 XL-protein GmbH PASYLATED VEGFR / PDGFR FUSION PROTEINS AND THEIR USE IN THERAPY
EP3720852A1 (en) 2017-12-04 2020-10-14 Friedrich-Alexander-Universität Erlangen-Nürnberg Fluorophenyl substituted muscarinic receptor ligands with selectivity for m3 over m2
KR20220001259A (ko) 2020-06-29 2022-01-05 (주)아모레퍼시픽 표면처리된 무기입자, 이의 제조방법, 이의 분산액 및 이를 포함하는 화장료 조성물

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE759460A (fr) * 1969-11-26 1971-05-26 Knoll Ag Nouveaux carbamates et leur procede de preparation
GB8600978D0 (en) * 1986-01-16 1986-02-19 Beecham Group Plc Compounds
IT1228293B (it) * 1989-02-06 1991-06-07 Angeli Inst Spa Benzoderivati di composti eterociclici contenenti azoto.
DE4108393A1 (de) * 1991-03-15 1992-09-17 Boehringer Ingelheim Kg Neue ester bi- und tricyclischer aminoalkohole, ihre herstellung und ihre verwendung in arzneimitteln
AU7545894A (en) * 1993-09-02 1995-03-22 Yamanouchi Pharmaceutical Co., Ltd. Carbamate derivative and medicine containing the same
CA2182568A1 (en) * 1994-02-10 1995-08-17 Makoto Takeuchi Novel carbamate derivative and medicinal composition containing the same
CA2249410C (en) * 1996-03-20 2007-06-12 Wake Forest University Sigma-2 receptors as biomarkers of tumor cell proliferation

Also Published As

Publication number Publication date
NO20053089L (no) 2005-06-23
ZA200502946B (en) 2005-11-23
UA81649C2 (ru) 2008-01-25
RS20050384A (en) 2007-12-31
PL376638A1 (pl) 2006-01-09
CA2507110C (en) 2012-07-10
JP4754829B2 (ja) 2011-08-24
CA2507110A1 (en) 2004-06-10
EA200500775A1 (ru) 2005-12-29
NO20053089D0 (no) 2005-06-23
ES2304538T3 (es) 2008-10-16
JP2006514010A (ja) 2006-04-27
KR20050086821A (ko) 2005-08-30
BR0316549A (pt) 2005-10-04
EP1567526A1 (de) 2005-08-31
DE50309655D1 (de) 2008-05-29
MXPA05005443A (es) 2005-08-03
CN1717408A (zh) 2006-01-04
DE10255040A1 (de) 2004-06-03
HRP20050465A2 (en) 2006-10-31
AU2003289880A1 (en) 2004-06-18
ATE392424T1 (de) 2008-05-15
EP1567526B1 (de) 2008-04-16
WO2004048373A1 (de) 2004-06-10

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