HRP20050465A2 - Carbamic acid esters with an anticholinergic action - Google Patents

Carbamic acid esters with an anticholinergic action

Info

Publication number
HRP20050465A2
HRP20050465A2 HR20050465A HRP20050465A HRP20050465A2 HR P20050465 A2 HRP20050465 A2 HR P20050465A2 HR 20050465 A HR20050465 A HR 20050465A HR P20050465 A HRP20050465 A HR P20050465A HR P20050465 A2 HRP20050465 A2 HR P20050465A2
Authority
HR
Croatia
Prior art keywords
carbamic acid
acid esters
anticholinergic action
anticholinergic
action
Prior art date
Application number
HR20050465A
Other languages
Croatian (hr)
Inventor
Grauert Matthias
Hoffmann Matthias
Michael
Speck Georg
Breitfelder Steffen
Original Assignee
Boehringer Ingelheim Pharma Gmbh & Co.Kg.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma Gmbh & Co.Kg. filed Critical Boehringer Ingelheim Pharma Gmbh & Co.Kg.
Publication of HRP20050465A2 publication Critical patent/HRP20050465A2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

The invention relates to novel carbamic acid esters of general formula (1), in which X<-> and the groups A, R<1>, R<2>, R<3> and R<4> can be defined as cited in the claims and the description. The invention also relates to a method for producing said esters and to their use as medicaments, in particular medicaments with an anticholinergic action.
HR20050465A 2002-11-26 2005-05-25 Carbamic acid esters with an anticholinergic action HRP20050465A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10255040A DE10255040A1 (en) 2002-11-26 2002-11-26 New carbamic acid esters with anticholinergic activity
PCT/EP2003/012912 WO2004048373A1 (en) 2002-11-26 2003-11-19 Carbamic acid esters with an anticholinergic action

Publications (1)

Publication Number Publication Date
HRP20050465A2 true HRP20050465A2 (en) 2006-10-31

Family

ID=32240420

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20050465A HRP20050465A2 (en) 2002-11-26 2005-05-25 Carbamic acid esters with an anticholinergic action

Country Status (20)

Country Link
EP (1) EP1567526B1 (en)
JP (1) JP4754829B2 (en)
KR (1) KR20050086821A (en)
CN (1) CN1717408A (en)
AT (1) ATE392424T1 (en)
AU (1) AU2003289880A1 (en)
BR (1) BR0316549A (en)
CA (1) CA2507110C (en)
DE (2) DE10255040A1 (en)
EA (1) EA200500775A1 (en)
EC (1) ECSP055803A (en)
ES (1) ES2304538T3 (en)
HR (1) HRP20050465A2 (en)
MX (1) MXPA05005443A (en)
NO (1) NO20053089L (en)
PL (1) PL376638A1 (en)
RS (1) RS20050384A (en)
UA (1) UA81649C2 (en)
WO (1) WO2004048373A1 (en)
ZA (1) ZA200502946B (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004106333A1 (en) 2003-05-28 2004-12-09 Theravance, Inc. Azabicycloalkane compounds as muscarinic receptor antagonists
TW200534855A (en) * 2004-01-13 2005-11-01 Glaxo Group Ltd Muscarinic acetylcholine receptor antagonists
JP2008505118A (en) * 2004-06-30 2008-02-21 グラクソ　グループ　リミテッド Muscarinic acetylcholine receptor antagonist
JP2008520573A (en) * 2004-11-15 2008-06-19 グラクソ グループ リミテッド Novel M3 muscarinic acetylcholine receptor antagonist
US20090012116A1 (en) * 2005-07-11 2009-01-08 Naresh Kumar Muscarinic Receptor Antagonists
JP2009519310A (en) * 2005-12-16 2009-05-14 アージェンタ ディスカバリー リミテッド Cyclic amine derivatives and their use
KR20090107567A (en) 2007-02-09 2009-10-13 아스텔라스세이야쿠 가부시키가이샤 Aza-bridged-ring compound
SG10202110259QA (en) 2017-10-05 2021-10-28 Fulcrum Therapeutics Inc Use of p38 inhibitors to reduce expression of dux4
US10342786B2 (en) 2017-10-05 2019-07-09 Fulcrum Therapeutics, Inc. P38 kinase inhibitors reduce DUX4 and downstream gene expression for the treatment of FSHD
WO2019096226A1 (en) 2017-11-16 2019-05-23 Chengdu Easton Biopharmaceuticals Co., Ltd. Pasylated vegfr/pdgfr fusion proteins and their use in therapy
US20200308168A1 (en) 2017-12-04 2020-10-01 Friedrich-Alexander-Universität Erlangen-Nürnberg Fluorophenyl substituted muscarinic receptor ligands with selectivity for m3 over m2
KR20220001259A (en) 2020-06-29 2022-01-05 (주)아모레퍼시픽 Surface-treated inorganic particles, manufacturing method of the same, dispersion solution of the same and cosmetic composition comprising the same

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE759460A (en) * 1969-11-26 1971-05-26 Knoll Ag NEW CARBAMATES AND THEIR PREPARATION PROCESS
GB8600978D0 (en) * 1986-01-16 1986-02-19 Beecham Group Plc Compounds
IT1228293B (en) * 1989-02-06 1991-06-07 Angeli Inst Spa BENZODERIVATES OF HETEROCYCLIC COMPOUNDS CONTAINING NITROGEN.
DE4108393A1 (en) * 1991-03-15 1992-09-17 Boehringer Ingelheim Kg NEW ESTERS BI-AND TRICYCLIC AMINO ALCOHOLS, THEIR PREPARATION AND THEIR USE IN MEDICINAL PRODUCTS
AU7545894A (en) * 1993-09-02 1995-03-22 Yamanouchi Pharmaceutical Co., Ltd. Carbamate derivative and medicine containing the same
AU685225B2 (en) * 1994-02-10 1998-01-15 Yamanouchi Pharmaceutical Co., Ltd. Novel carbamate derivative and medicinal composition containing the same
EP0888345B1 (en) * 1996-03-20 2010-05-05 Wake Forest University Health Sciences Sigma-2 receptors as biomarkers of tumor cell proliferation

Also Published As

Publication number Publication date
NO20053089D0 (en) 2005-06-23
ZA200502946B (en) 2005-11-23
ES2304538T3 (en) 2008-10-16
AU2003289880A1 (en) 2004-06-18
CA2507110C (en) 2012-07-10
JP2006514010A (en) 2006-04-27
MXPA05005443A (en) 2005-08-03
BR0316549A (en) 2005-10-04
ECSP055803A (en) 2005-08-11
JP4754829B2 (en) 2011-08-24
KR20050086821A (en) 2005-08-30
DE50309655D1 (en) 2008-05-29
RS20050384A (en) 2007-12-31
NO20053089L (en) 2005-06-23
CN1717408A (en) 2006-01-04
UA81649C2 (en) 2008-01-25
EA200500775A1 (en) 2005-12-29
PL376638A1 (en) 2006-01-09
EP1567526B1 (en) 2008-04-16
DE10255040A1 (en) 2004-06-03
CA2507110A1 (en) 2004-06-10
ATE392424T1 (en) 2008-05-15
EP1567526A1 (en) 2005-08-31
WO2004048373A1 (en) 2004-06-10

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