ECSP034416A - Compuestos de ciclicos sustituidos de aminometilo y medicamentos que lo contienen - Google Patents

Compuestos de ciclicos sustituidos de aminometilo y medicamentos que lo contienen

Info

Publication number
ECSP034416A
ECSP034416A EC2003004416A ECSP034416A ECSP034416A EC SP034416 A ECSP034416 A EC SP034416A EC 2003004416 A EC2003004416 A EC 2003004416A EC SP034416 A ECSP034416 A EC SP034416A EC SP034416 A ECSP034416 A EC SP034416A
Authority
EC
Ecuador
Prior art keywords
compounds
aminometilo
cycles
replaced
production
Prior art date
Application number
EC2003004416A
Other languages
English (en)
Inventor
Oswald Karl Zimmer
Wolfgang Alfred Werner Strassburger
Babette Yvonne Koegel
Original Assignee
Gruenenthal Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruenenthal Gmbh filed Critical Gruenenthal Gmbh
Publication of ECSP034416A publication Critical patent/ECSP034416A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D335/06—Benzothiopyrans; Hydrogenated benzothiopyrans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/06—Anti-spasmodics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/26—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
    • C07C211/29—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by halogen atoms or by nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C215/64—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/74—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • C07D313/02—Seven-membered rings
    • C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D313/08—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D337/00—Heterocyclic compounds containing rings of more than six members having one sulfur atom as the only ring hetero atom
    • C07D337/02—Seven-membered rings
    • C07D337/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D337/08—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/12—One of the condensed rings being a six-membered aromatic ring the other ring being at least seven-membered

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Urology & Nephrology (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrane Compounds (AREA)

Abstract

La invención se relaciona con los compuestos de cíclicos constituidos de aminometiloide fórmula general 1A e 1B, métodos para la producción de los mismos, intermediarios en tales métodos de producción, un medicamento conteniendo al menos uno de tales compuestos de cíclicos sustituidos de aminometilo, el uso de dichos compuestos de cíclicos sustituidos de aminometilo para la producción de un medicamento para el tratamiento del dolor, incontinencia, pruritis, tinnitus aurium y/o diarrea y composiciones farmacéuticas conteniendo tales compuestos.
EC2003004416A 2000-07-10 2003-01-06 Compuestos de ciclicos sustituidos de aminometilo y medicamentos que lo contienen ECSP034416A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10033459A DE10033459A1 (de) 2000-07-10 2000-07-10 Cyclische substituierte Aminomethylverbindungen und diese Verbindungen enthaltende Arzeimittel

Publications (1)

Publication Number Publication Date
ECSP034416A true ECSP034416A (es) 2003-04-25

Family

ID=7648406

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2003004416A ECSP034416A (es) 2000-07-10 2003-01-06 Compuestos de ciclicos sustituidos de aminometilo y medicamentos que lo contienen

Country Status (28)

Country Link
US (1) US6890952B2 (es)
EP (1) EP1299373B1 (es)
JP (1) JP2004504394A (es)
KR (1) KR100821113B1 (es)
CN (1) CN1179958C (es)
AR (1) AR032464A1 (es)
AT (1) ATE286891T1 (es)
AU (2) AU6912401A (es)
BR (1) BR0112447A (es)
CA (1) CA2415196A1 (es)
CZ (1) CZ301135B6 (es)
DE (2) DE10033459A1 (es)
EC (1) ECSP034416A (es)
ES (1) ES2234851T3 (es)
HK (1) HK1054932A1 (es)
HU (1) HUP0302817A3 (es)
IL (2) IL153825A0 (es)
MX (1) MXPA02012925A (es)
MY (1) MY134060A (es)
NO (1) NO20030105L (es)
NZ (1) NZ523089A (es)
PE (1) PE20020255A1 (es)
PL (1) PL204123B1 (es)
PT (1) PT1299373E (es)
RU (1) RU2003102610A (es)
SK (1) SK372003A3 (es)
WO (1) WO2002008218A1 (es)
ZA (1) ZA200301048B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102004034619A1 (de) 2004-07-16 2006-02-23 Grünenthal GmbH Substituierte Aminoverbindungen als 5-HT/NA Uptakehemmer
EP1893568A2 (en) * 2005-06-07 2008-03-05 Neurocrine Biosciences, Inc. Monoamine re-uptake inhibitors and methods relating thereto

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE922703C (de) 1951-02-03 1955-01-24 Hans Kenner Stanzvorlage zum Ausstanzen von Reissverschlusskrampen und Verfahren sowie Vorrichtung zum Herstellen derselben
CH394229A (de) * 1958-03-20 1965-06-30 Ciba Geigy Verfahren zur Herstellung von 3-Aralkyl-2-tert.-aminoalkyl-indenen
US3072716A (en) * 1959-03-18 1963-01-08 Ciba Geigy Corp Substituted indenes
US3142682A (en) * 1961-11-21 1964-07-28 Ciba Geigy Corp Tertiary amino derivatives of chromans and homo-chromans
US3956391A (en) * 1973-06-04 1976-05-11 Sandoz, Inc. Amino substituted tetrahydropleiadenes
JPS61130287A (ja) * 1984-11-30 1986-06-18 Suntory Ltd １−ベンズオキセピン誘導体
DE19805370A1 (de) * 1997-03-14 1998-09-17 Gruenenthal Gmbh Substituierte Aminoverbindungen und ihre Verwendung als analgetisch wirksame Substanzen
DE19755480A1 (de) * 1997-12-13 1999-06-24 Gruenenthal Gmbh Substituierte heterocyclische Benzocycloalkene und ihre Verwendung als analgetisch wirksame Substanzen

Also Published As

Publication number Publication date
PE20020255A1 (es) 2002-05-18
CN1441796A (zh) 2003-09-10
CN1179958C (zh) 2004-12-15
NZ523089A (en) 2005-07-29
BR0112447A (pt) 2003-07-08
WO2002008218A1 (de) 2002-01-31
DE10033459A1 (de) 2002-01-24
RU2003102610A (ru) 2004-07-10
KR100821113B1 (ko) 2008-04-11
CA2415196A1 (en) 2003-01-08
ES2234851T3 (es) 2005-07-01
IL153825A (en) 2008-04-13
DE50105073D1 (de) 2005-02-17
CZ200388A3 (cs) 2003-04-16
EP1299373B1 (de) 2005-01-12
MY134060A (en) 2007-11-30
KR20030040351A (ko) 2003-05-22
IL153825A0 (en) 2003-07-31
US20030166708A1 (en) 2003-09-04
US6890952B2 (en) 2005-05-10
PT1299373E (pt) 2005-05-31
HK1054932A1 (en) 2003-12-19
AU6912401A (en) 2002-02-05
SK372003A3 (en) 2003-06-03
HUP0302817A1 (hu) 2003-12-29
JP2004504394A (ja) 2004-02-12
NO20030105D0 (no) 2003-01-09
HUP0302817A3 (en) 2005-02-28
AR032464A1 (es) 2003-11-12
NO20030105L (no) 2003-02-05
EP1299373A1 (de) 2003-04-09
AU2001269124B2 (en) 2006-03-30
MXPA02012925A (es) 2003-05-15
ZA200301048B (en) 2004-05-06
PL204123B1 (pl) 2009-12-31
CZ301135B6 (cs) 2009-11-18
ATE286891T1 (de) 2005-01-15
PL360389A1 (en) 2004-09-06

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