EA202192438A1 - Способ и аппарат для восстановления почек - Google Patents

Способ и аппарат для восстановления почек

Info

Publication number
EA202192438A1
EA202192438A1 EA202192438A EA202192438A EA202192438A1 EA 202192438 A1 EA202192438 A1 EA 202192438A1 EA 202192438 A EA202192438 A EA 202192438A EA 202192438 A EA202192438 A EA 202192438A EA 202192438 A1 EA202192438 A1 EA 202192438A1
Authority
EA
Eurasian Patent Office
Prior art keywords
kidney
tpa
plasminogen
lys
injected
Prior art date
Application number
EA202192438A
Other languages
English (en)
Inventor
Микель Олауссон
Original Assignee
Углк Сайенс Аб
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Углк Сайенс Аб filed Critical Углк Сайенс Аб
Publication of EA202192438A1 publication Critical patent/EA202192438A1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0205—Chemical aspects
    • A01N1/021—Preservation or perfusion media, liquids, solids or gases used in the preservation of cells, tissue, organs or bodily fluids
    • A01N1/0226—Physiologically active agents, i.e. substances affecting physiological processes of cells and tissue to be preserved, e.g. anti-oxidants or nutrients
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0205—Chemical aspects
    • A01N1/021—Preservation or perfusion media, liquids, solids or gases used in the preservation of cells, tissue, organs or bodily fluids
    • A01N1/0221—Freeze-process protecting agents, i.e. substances protecting cells from effects of the physical process, e.g. cryoprotectants, osmolarity regulators like oncotic agents
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0236—Mechanical aspects
    • A01N1/0242—Apparatuses, i.e. devices used in the process of preservation of living parts, such as pumps, refrigeration devices or any other devices featuring moving parts and/or temperature controlling components
    • A01N1/0247—Apparatuses, i.e. devices used in the process of preservation of living parts, such as pumps, refrigeration devices or any other devices featuring moving parts and/or temperature controlling components for perfusion, i.e. for circulating fluid through organs, blood vessels or other living parts

Abstract

Предложены способ, устройство и жидкость для восстановления донорской почки, например, от донора, умершего от остановки сердца, причем почка подверглась теплой ишемии в течение 4 ч или более. На инструментальном столе после изъятия почки в нее вводят лиз-плазминоген, а через 15 мин вводят ТАП. Затем вводят гиперонкотическую циркуляционную жидкость, содержащую альбумин и электролиты, и обеспечивают ее циркуляцию через почку вместе с указанным лиз-плазминогеном и ТАП, причем давление циркуляции увеличивают от 20 до 70 мм рт.ст. в течение 30-75 мин, например пошагово по 5 мм рт.ст. каждые 5 мин. Затем почку оценивают по обычным критериям.
EA202192438A 2019-04-12 2020-04-12 Способ и аппарат для восстановления почек EA202192438A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE1930123 2019-04-12
PCT/SE2020/050380 WO2020209787A1 (en) 2019-04-12 2020-04-12 Method and apparatus for reconditioning kidneys

Publications (1)

Publication Number Publication Date
EA202192438A1 true EA202192438A1 (ru) 2022-01-28

Family

ID=72750508

Family Applications (1)

Application Number Title Priority Date Filing Date
EA202192438A EA202192438A1 (ru) 2019-04-12 2020-04-12 Способ и аппарат для восстановления почек

Country Status (12)

Country Link
US (1) US20220183273A1 (ru)
EP (1) EP3952644A4 (ru)
JP (1) JP2022528752A (ru)
KR (1) KR20210151202A (ru)
CN (1) CN113677201B (ru)
AU (1) AU2020270928A1 (ru)
CA (1) CA3134900A1 (ru)
EA (1) EA202192438A1 (ru)
IL (1) IL287036A (ru)
MX (1) MX2021012243A (ru)
SG (1) SG11202110554YA (ru)
WO (1) WO2020209787A1 (ru)

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5520912A (en) * 1993-07-02 1996-05-28 Immuno Aktiengesellschaft Prevention and treatment of ischemic events and reperfusion injury resulting therefrom using lys-plasminogen
AU8131794A (en) * 1993-11-02 1995-05-23 Emory University Composition for tissue and organ transplantation preservation
US6100082A (en) * 1997-09-23 2000-08-08 Hassanein; Waleed H. Perfusion apparatus and method including chemical compositions for maintaining an organ
AU6274899A (en) * 1998-09-29 2000-04-17 Organ Recovery Systems, Inc. Apparatus and method for maintaining and/or restoring viability of organs
EP1311154A2 (en) * 2000-08-25 2003-05-21 Organ Recovery Systems, Inc. Methods of thrombolytic organ treatment and repair
AU2002214443B2 (en) * 2000-11-03 2005-12-15 Vitrolife Ab Evaluation and preservation solution
US20020197252A1 (en) * 2001-04-10 2002-12-26 Renal Tech International Selective adsorption devices and systems
AU2003278186A1 (en) * 2002-10-15 2004-05-04 Agfa-Gevaert Polymer for heat-sensitive lithographic printing plate precursor
MX2011006995A (es) * 2008-12-30 2011-09-27 Thrombologic Aps Metodos para identificar pacientes criticamente enfermos en riesgo incrementado de desarrollar nsuficiencia organica y compuestos para el tratamiento de la misma.
EP2688541A4 (en) * 2011-03-23 2014-08-20 Vivoline Medical Ab DEVICE FOR MAINTAINING THE VITABILITY AND TRANSPORTABILITY OF REMOVED ORGANS
CN204763020U (zh) * 2015-02-16 2015-11-18 杭州电子科技大学 亚常温移植器官体外智能支持系统
JP2020523042A (ja) * 2017-03-27 2020-08-06 サイトソーベンツ・コーポレーション 中空糸フィルタモジュールおよび高分子収着剤の組合せで構成される体外循環回路を用いて血液から毒素を除去する方法
CN107156109A (zh) * 2017-05-31 2017-09-15 上海市杨浦区市东医院 一种离体器官保存系统

Also Published As

Publication number Publication date
WO2020209787A1 (en) 2020-10-15
AU2020270928A1 (en) 2021-10-21
WO2020209787A8 (en) 2021-10-14
CN113677201A (zh) 2021-11-19
US20220183273A1 (en) 2022-06-16
KR20210151202A (ko) 2021-12-13
IL287036A (en) 2021-12-01
EP3952644A1 (en) 2022-02-16
JP2022528752A (ja) 2022-06-15
EP3952644A4 (en) 2023-06-07
CA3134900A1 (en) 2020-10-15
CN113677201B (zh) 2023-09-26
MX2021012243A (es) 2021-12-10
SG11202110554YA (en) 2021-10-28

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