EA202191771A1 - КОМПОЗИЦИИ НА ОСНОВЕ RNAi ПРОТИВ ВИРУСА ГЕПАТИТА В (HBV) И СПОСОБЫ ИХ ПРИМЕНЕНИЯ - Google Patents

КОМПОЗИЦИИ НА ОСНОВЕ RNAi ПРОТИВ ВИРУСА ГЕПАТИТА В (HBV) И СПОСОБЫ ИХ ПРИМЕНЕНИЯ

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EA202191771A1
EA202191771A1 EA202191771A EA202191771A EA202191771A1 EA 202191771 A1 EA202191771 A1 EA 202191771A1 EA 202191771 A EA202191771 A EA 202191771A EA 202191771 A EA202191771 A EA 202191771A EA 202191771 A1 EA202191771 A1 EA 202191771A1
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Eurasian Patent Office
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hbv
methods
virus
rnai
application
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EA202191771A
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English (en)
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Грегори Хинкл
Лаура Сепп-Лорензино
Васант Джадхав
Мартин Майер
Стюарт Милстейн
Мутхиах Манохаран
Каллантхоттатхил Г. Раджив
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Элнилэм Фармасьютикалз, Инк.
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Publication of EA202191771A1 publication Critical patent/EA202191771A1/ru

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Abstract

Изобретение относится к средствам для RNAi, например двухнитевым средствам для RNAi, целенаправленно воздействующим на геном вируса гепатита B (HBV), к способам применения таких средств для RNAi для ингибирования экспрессии одного или нескольких генов HBV и к способам лечения субъектов с инфекцией HBV и/или ассоциированным с HBV нарушением, например хронической инфекцией, вызванной вирусом гепатита B.
EA202191771A 2015-03-24 2015-11-10 КОМПОЗИЦИИ НА ОСНОВЕ RNAi ПРОТИВ ВИРУСА ГЕПАТИТА В (HBV) И СПОСОБЫ ИХ ПРИМЕНЕНИЯ EA202191771A1 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201562137464P 2015-03-24 2015-03-24

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EA202191771A1 true EA202191771A1 (ru) 2022-01-31

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Application Number Title Priority Date Filing Date
EA202191771A EA202191771A1 (ru) 2015-03-24 2015-11-10 КОМПОЗИЦИИ НА ОСНОВЕ RNAi ПРОТИВ ВИРУСА ГЕПАТИТА В (HBV) И СПОСОБЫ ИХ ПРИМЕНЕНИЯ
EA201791014A EA039127B1 (ru) 2015-03-24 2015-11-10 КОМПОЗИЦИИ НА ОСНОВЕ iRNA ПРОТИВ ВИРУСА ГЕПАТИТА В (HBV) И СПОСОБЫ ИХ ПРИМЕНЕНИЯ

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EA201791014A EA039127B1 (ru) 2015-03-24 2015-11-10 КОМПОЗИЦИИ НА ОСНОВЕ iRNA ПРОТИВ ВИРУСА ГЕПАТИТА В (HBV) И СПОСОБЫ ИХ ПРИМЕНЕНИЯ

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Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020255007A1 (en) * 2019-06-18 2020-12-24 Janssen Sciences Ireland Unlimited Company Combination of hepatitis b virus (hbv) vaccines and hbv-targeting rnai

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070027099A1 (en) * 2003-05-19 2007-02-01 Lin Marie C Gene therapy of HBV infection via adeno-associated viral vector mediated long term expression of small hairpin RNA (shRNA)
US7067249B2 (en) * 2003-05-19 2006-06-27 The University Of Hong Kong Inhibition of hepatitis B virus (HBV) replication by RNA interference
CN101314047A (zh) * 2007-06-01 2008-12-03 中国科学院微生物研究所 治疗病毒感染的方法及其药物
CN103275971A (zh) * 2008-06-13 2013-09-04 厦门大学 可用于乙型肝炎病毒感染治疗的rna干扰靶点
CA2807307C (en) * 2010-08-17 2021-02-09 Merck Sharp & Dohme Corp. Rna interference mediated inhibition of hepatitis b virus (hbv) gene expression using short interfering nucleic acid (sina)
EP3505528B1 (en) * 2011-04-21 2020-11-25 Ionis Pharmaceuticals, Inc. Modulation of hepatitis b virus (hbv) expression
CN103014045B (zh) * 2012-12-30 2014-09-17 中国人民解放军第三军医大学 表达特异性HBV shRNA的重组HBV载体及其构建方法和应用

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EA039127B1 (ru) 2021-12-08

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