EA201992348A1 - АНТИГЕН-СВЯЗЫВАЮЩИЕ БЕЛКИ, ВЗАИМОДЕЙСТВУЮЩИЕ С Jagged1 - Google Patents
АНТИГЕН-СВЯЗЫВАЮЩИЕ БЕЛКИ, ВЗАИМОДЕЙСТВУЮЩИЕ С Jagged1Info
- Publication number
- EA201992348A1 EA201992348A1 EA201992348A EA201992348A EA201992348A1 EA 201992348 A1 EA201992348 A1 EA 201992348A1 EA 201992348 A EA201992348 A EA 201992348A EA 201992348 A EA201992348 A EA 201992348A EA 201992348 A1 EA201992348 A1 EA 201992348A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- jagged1
- antigen
- binding proteins
- proteins interacting
- interacting
- Prior art date
Links
- 102000049556 Jagged-1 Human genes 0.000 title abstract 2
- 102000025171 antigen binding proteins Human genes 0.000 title abstract 2
- 108091000831 antigen binding proteins Proteins 0.000 title abstract 2
- 108700003486 Jagged-1 Proteins 0.000 title 1
- 108700037966 Protein jagged-1 Proteins 0.000 title 1
- 208000019693 Lung disease Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2896—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/54—F(ab')2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Endocrinology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
Предусмотрены способы лечения состояний, связанных с заболеванием легкого, с применением антиген-связывающего белка, специфичного в отношении полипептида Jagged1.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201762512805P | 2017-05-31 | 2017-05-31 | |
PCT/US2018/035209 WO2018222770A1 (en) | 2017-05-31 | 2018-05-30 | Anti-jagged1 antigen binding proteins |
Publications (1)
Publication Number | Publication Date |
---|---|
EA201992348A1 true EA201992348A1 (ru) | 2020-03-24 |
Family
ID=62683483
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA201992348A EA201992348A1 (ru) | 2017-05-31 | 2018-05-30 | АНТИГЕН-СВЯЗЫВАЮЩИЕ БЕЛКИ, ВЗАИМОДЕЙСТВУЮЩИЕ С Jagged1 |
Country Status (23)
Country | Link |
---|---|
US (3) | US11028180B2 (ru) |
EP (1) | EP3630820A1 (ru) |
JP (1) | JP7222614B2 (ru) |
KR (1) | KR20200012848A (ru) |
CN (1) | CN110621695B (ru) |
AR (1) | AR111767A1 (ru) |
AU (1) | AU2018275231A1 (ru) |
BR (1) | BR112019023118A2 (ru) |
CA (1) | CA3059975A1 (ru) |
CL (1) | CL2019003167A1 (ru) |
CO (1) | CO2019012204A2 (ru) |
CR (1) | CR20190513A (ru) |
EA (1) | EA201992348A1 (ru) |
JO (1) | JOP20190259A1 (ru) |
MA (1) | MA48777A (ru) |
MX (1) | MX2019013211A (ru) |
PE (1) | PE20200487A1 (ru) |
PH (1) | PH12019502449A1 (ru) |
SG (1) | SG11201909529XA (ru) |
TW (1) | TW201908339A (ru) |
UY (1) | UY37752A (ru) |
WO (1) | WO2018222770A1 (ru) |
ZA (1) | ZA201906821B (ru) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2685424T3 (es) | 2014-02-12 | 2018-10-09 | F. Hoffmann-La Roche Ag | Anticuerpos anti-Jagged1 y procedimientos de uso |
JOP20190259A1 (ar) * | 2017-05-31 | 2019-10-31 | Amgen Inc | بروتينات ربط مولد ضد مضادة لـ jagged1 |
CN111471643B (zh) * | 2020-04-09 | 2020-12-29 | 创芯国际生物科技(广州)有限公司 | 一种通用型上呼吸道粘膜类器官的培养基及培养方法 |
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JOP20190259A1 (ar) * | 2017-05-31 | 2019-10-31 | Amgen Inc | بروتينات ربط مولد ضد مضادة لـ jagged1 |
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2017
- 2017-06-16 JO JOP/2019/0259A patent/JOP20190259A1/ar unknown
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2018
- 2018-05-30 MA MA048777A patent/MA48777A/fr unknown
- 2018-05-30 WO PCT/US2018/035209 patent/WO2018222770A1/en active Application Filing
- 2018-05-30 MX MX2019013211A patent/MX2019013211A/es unknown
- 2018-05-30 EA EA201992348A patent/EA201992348A1/ru unknown
- 2018-05-30 PE PE2019002278A patent/PE20200487A1/es unknown
- 2018-05-30 CN CN201880029832.2A patent/CN110621695B/zh active Active
- 2018-05-30 CR CR20190513A patent/CR20190513A/es unknown
- 2018-05-30 BR BR112019023118-8A patent/BR112019023118A2/pt unknown
- 2018-05-30 CA CA3059975A patent/CA3059975A1/en active Pending
- 2018-05-30 AU AU2018275231A patent/AU2018275231A1/en active Pending
- 2018-05-30 SG SG11201909529X patent/SG11201909529XA/en unknown
- 2018-05-30 KR KR1020197032633A patent/KR20200012848A/ko not_active Application Discontinuation
- 2018-05-30 US US15/993,448 patent/US11028180B2/en active Active
- 2018-05-30 EP EP18732590.7A patent/EP3630820A1/en active Pending
- 2018-05-31 AR ARP180101447A patent/AR111767A1/es unknown
- 2018-05-31 UY UY0001037752A patent/UY37752A/es not_active Application Discontinuation
- 2018-05-31 TW TW107118769A patent/TW201908339A/zh unknown
- 2018-05-31 JP JP2018104357A patent/JP7222614B2/ja active Active
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2019
- 2019-10-16 ZA ZA2019/06821A patent/ZA201906821B/en unknown
- 2019-10-29 PH PH12019502449A patent/PH12019502449A1/en unknown
- 2019-10-30 CO CONC2019/0012204A patent/CO2019012204A2/es unknown
- 2019-11-04 CL CL2019003167A patent/CL2019003167A1/es unknown
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2021
- 2021-05-13 US US17/320,128 patent/US11897963B2/en active Active
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2022
- 2022-02-16 US US17/672,889 patent/US11897965B2/en active Active
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US20210340270A1 (en) | 2021-11-04 |
WO2018222770A1 (en) | 2018-12-06 |
MX2019013211A (es) | 2020-07-27 |
PE20200487A1 (es) | 2020-03-03 |
CN110621695B (zh) | 2023-10-17 |
US11897963B2 (en) | 2024-02-13 |
CA3059975A1 (en) | 2018-12-06 |
PH12019502449A1 (en) | 2020-07-20 |
US11028180B2 (en) | 2021-06-08 |
JP2018203735A (ja) | 2018-12-27 |
MA48777A (fr) | 2020-04-08 |
ZA201906821B (en) | 2021-06-30 |
US20190023802A1 (en) | 2019-01-24 |
TW201908339A (zh) | 2019-03-01 |
CN110621695A (zh) | 2019-12-27 |
CL2019003167A1 (es) | 2020-03-20 |
CO2019012204A2 (es) | 2020-02-07 |
AU2018275231A1 (en) | 2019-10-31 |
JP7222614B2 (ja) | 2023-02-15 |
EP3630820A1 (en) | 2020-04-08 |
US11897965B2 (en) | 2024-02-13 |
BR112019023118A2 (pt) | 2020-10-20 |
CR20190513A (es) | 2020-01-17 |
KR20200012848A (ko) | 2020-02-05 |
UY37752A (es) | 2019-01-02 |
US20220169744A1 (en) | 2022-06-02 |
JOP20190259A1 (ar) | 2019-10-31 |
SG11201909529XA (en) | 2019-11-28 |
AR111767A1 (es) | 2019-08-14 |
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