EA201991275A1 - Антисептическая композиция, содержащая поливинилпирролидон и унитиол, и применение такой композиции - Google Patents

Антисептическая композиция, содержащая поливинилпирролидон и унитиол, и применение такой композиции

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Publication number
EA201991275A1
EA201991275A1 EA201991275A EA201991275A EA201991275A1 EA 201991275 A1 EA201991275 A1 EA 201991275A1 EA 201991275 A EA201991275 A EA 201991275A EA 201991275 A EA201991275 A EA 201991275A EA 201991275 A1 EA201991275 A1 EA 201991275A1
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Eurasian Patent Office
Prior art keywords
unitiol
antiseptic
compositions
composition
pyrrolidone
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EA201991275A
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English (en)
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EA037319B1 (ru
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Publication of EA037319B1 publication Critical patent/EA037319B1/ru

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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
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    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/047Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
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    • A61K31/00Medicinal preparations containing organic active ingredients
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/10Sulfides; Sulfoxides; Sulfones
    • AHUMAN NECESSITIES
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    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
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    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
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    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/498Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
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    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
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    • A61K31/74Synthetic polymeric materials
    • A61K31/785Polymers containing nitrogen
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    • A61K31/79Polymers of vinyl pyrrolidone
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    • A61K47/20Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
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    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
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    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
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Abstract

Изобретение относится к новым антисептическим композициям на полимерной основе, предназначенным для обработки ран и/или для использования при хирургических операциях, образующим на поверхности раны пленку и обладающим антисептическим, обезболивающим и антитоксическим действием. Композиции по изобретению содержат поливинилпирролидон со среднемассовой молекулярной массой в диапазоне от 1000000 до 3000000 Да, один или несколько антисептиков, унитиол, диметилсульфоксид и один или несколько анестетиков, предпочтительно анестетиков местного действия. Кроме того, настоящее изобретение относится к применению композиций по изобретению в качестве средства для обработки ран, а также к способам обработки ран с использованием композиций по изобретению, включающим операцию нанесения композиции по изобретению на раневую поверхность.
EA201991275A 2017-02-22 2017-12-14 Антисептическая композиция, содержащая поливинилпирролидон и унитиол, её применение, способ обработки ран EA037319B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
RU2017106061A RU2649785C1 (ru) 2017-02-22 2017-02-22 Антисептическая композиция, содержащая поливинилпирролидон и унитиол, применение такой композиции и способ обработки ран с ее использованием
PCT/RU2017/000905 WO2018156051A1 (en) 2017-02-22 2017-12-14 Antiseptic composition comprising polyvinylpyrrolidone and unithiol and use of the composition

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EA201991275A1 true EA201991275A1 (ru) 2019-11-29
EA037319B1 EA037319B1 (ru) 2021-03-11

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US (1) US11045551B2 (ru)
EP (1) EP3585399B1 (ru)
JP (1) JP6690816B2 (ru)
KR (1) KR102096257B1 (ru)
CN (1) CN110198721B (ru)
AU (1) AU2017400650B2 (ru)
BR (1) BR112019016560A2 (ru)
CA (1) CA3054002C (ru)
CL (1) CL2019002259A1 (ru)
EA (1) EA037319B1 (ru)
GE (1) GEP20207136B (ru)
MA (1) MA46159B1 (ru)
MX (1) MX2019009761A (ru)
PL (1) PL3585399T3 (ru)
RU (1) RU2649785C1 (ru)
SG (1) SG11201903097UA (ru)
UA (1) UA121949C2 (ru)
WO (1) WO2018156051A1 (ru)
ZA (1) ZA201905343B (ru)

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MA46159A1 (fr) 2021-04-30
CN110198721A (zh) 2019-09-03
AU2017400650B2 (en) 2019-09-26
US11045551B2 (en) 2021-06-29
PL3585399T3 (pl) 2022-05-30
RU2649785C1 (ru) 2018-04-04
CN110198721B (zh) 2022-06-07
EP3585399B1 (en) 2022-02-09
EA037319B1 (ru) 2021-03-11
KR102096257B1 (ko) 2020-04-06
MA46159B1 (fr) 2022-04-29
UA121949C2 (uk) 2020-08-10
SG11201903097UA (en) 2019-09-27
ZA201905343B (en) 2021-08-25
KR20190099338A (ko) 2019-08-26
GEP20207136B (en) 2020-07-27
JP6690816B2 (ja) 2020-04-28
BR112019016560A2 (pt) 2020-03-31
MX2019009761A (es) 2019-10-07
EP3585399A1 (en) 2020-01-01
CA3054002C (en) 2021-07-20
AU2017400650A1 (en) 2019-07-18
US20190381176A1 (en) 2019-12-19
JP2020506164A (ja) 2020-02-27
WO2018156051A1 (en) 2018-08-30
CL2019002259A1 (es) 2020-01-03
CA3054002A1 (en) 2018-08-30

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