EA201892201A1 - Неинвазивная диагностика неалкогольного стеатогепатита - Google Patents

Неинвазивная диагностика неалкогольного стеатогепатита

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Publication number
EA201892201A1
EA201892201A1 EA201892201A EA201892201A EA201892201A1 EA 201892201 A1 EA201892201 A1 EA 201892201A1 EA 201892201 A EA201892201 A EA 201892201A EA 201892201 A EA201892201 A EA 201892201A EA 201892201 A1 EA201892201 A1 EA 201892201A1
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Prior art keywords
steatopepatitis
alcohol
invasive diagnostics
diagnostics
nash
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EA201892201A
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English (en)
Inventor
Рафаэль Дартей
Женевьев Кордоннье
Джон Брозек
Эмили Прака
Фуад Бен Судрик
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Женфит
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Publication of EA201892201A1 publication Critical patent/EA201892201A1/ru

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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/08—Hepato-biliairy disorders other than hepatitis
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  • Health & Medical Sciences (AREA)
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Abstract

Настоящее изобретение относится к новому способу диагностики неалкогольного стеатогепатита (NASH) и классификации индивидуума как потенциального реципиента лечения NASH.
EA201892201A 2016-03-30 2017-03-30 Неинвазивная диагностика неалкогольного стеатогепатита EA201892201A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP16163048 2016-03-30
PCT/EP2017/057633 WO2017167934A1 (en) 2016-03-30 2017-03-30 Non-invasive diagnostic of non-alcoholic steatohepatitis

Publications (1)

Publication Number Publication Date
EA201892201A1 true EA201892201A1 (ru) 2019-03-29

Family

ID=55806131

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201892201A EA201892201A1 (ru) 2016-03-30 2017-03-30 Неинвазивная диагностика неалкогольного стеатогепатита

Country Status (15)

Country Link
US (1) US12104209B2 (ru)
EP (2) EP3436600B1 (ru)
JP (2) JP7418959B2 (ru)
KR (1) KR102646698B1 (ru)
CN (1) CN109072302B (ru)
AU (2) AU2017242818B2 (ru)
BR (1) BR112018069560A2 (ru)
CA (1) CA3018133A1 (ru)
EA (1) EA201892201A1 (ru)
IL (1) IL261814A (ru)
MX (1) MX2018011633A (ru)
PH (1) PH12018502057A1 (ru)
SG (1) SG11201808192RA (ru)
WO (1) WO2017167934A1 (ru)
ZA (1) ZA201807083B (ru)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12104209B2 (en) * 2016-03-30 2024-10-01 Genfit Non-invasive diagnostic of non-alcoholic steatohepatitis
US10624944B2 (en) * 2017-06-19 2020-04-21 Creative Bio-Peptides Inc. Anti-inflammatory peptides for treating non-alcoholic steatohepatitis (NASH)
US20200340060A1 (en) * 2017-11-13 2020-10-29 Gilead Sciences, Inc. Compositions and methods for identifying and treating liver diseases and monitoring treatment outcomes
JP7239139B2 (ja) * 2018-08-03 2023-03-14 国立大学法人金沢大学 肝硬変の診断方法、非アルコール性脂肪肝炎及び肝細胞がんの合併症の診断方法並びに非アルコール性脂肪肝炎及び食道胃静脈瘤の合併症の診断方法
SG11202101863YA (en) * 2018-08-30 2021-03-30 Terns Pharmaceuticals Inc Treating liver disorders
JP2022524823A (ja) 2019-03-13 2022-05-10 ジェンフィット 非アルコール性脂肪性肝炎の診断
BR112021020664A2 (pt) 2019-04-16 2021-12-07 Genfit Composições e métodos para a estabilização de micro-rna
WO2021149719A1 (ja) * 2020-01-24 2021-07-29 アルプスアルパイン株式会社 ｍｉＲＮＡの発現レベルをがんの指標として用いる方法
JP2023548840A (ja) * 2020-10-30 2023-11-21 ジェンフィット 肝線維化を診断する方法
RU2760092C1 (ru) * 2021-03-29 2021-11-22 Федеральное бюджетное учреждение науки "Федеральный научный центр медико-профилактических технологий управления рисками здоровью населения" Федеральной службы по надзору в сфере защиты прав потребителей и благополучия человека (ФБУН "ФНЦ медико-профилактических технологий управления рисками здоровью Способ диагностики неалкогольной жировой болезни печени у мужчин европейской популяции при скрининговых обследованиях
CN113160983A (zh) * 2021-04-09 2021-07-23 南京医科大学附属逸夫医院 一种代谢相关脂肪性肝病临床预测模型
US20220340962A1 (en) 2021-04-22 2022-10-27 Genfit Quantitative detection of micro-rnas
KR102521638B1 (ko) * 2021-05-21 2023-04-14 브렉소젠 주식회사 비알코올성 지방간질환의 진단용 마커
MX2023015258A (es) 2021-06-16 2024-04-29 Genfit Metodo para la evaluacion del riesgo de ena en pacientes que tienen un trastorno metabolico.
WO2023194593A1 (en) * 2022-04-08 2023-10-12 Genfit Improved diagnosis of nonalcoholic steatohepatitis
CN116959734A (zh) * 2023-05-17 2023-10-27 南方医科大学南方医院 一种代谢相关脂肪性肝病发病的预测方法及系统

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2841784B1 (fr) 2002-07-08 2007-03-02 Composition a base de derives de 1,3-diphenylprop-2en-1-one substitues, preparation et utilisations
US7856319B2 (en) 2005-02-03 2010-12-21 Assistance Publique-Hopitaux De Paris (Ap-Hp) Diagnosis method of alcoholic steato-hepatitis using biochemical markers
WO2012012051A2 (en) * 2010-07-20 2012-01-26 Trustees Of Dartmouth College Method for multicolor codetection of microrna and proteins
WO2012105590A1 (ja) * 2011-02-01 2012-08-09 アステラス製薬株式会社 非アルコール性脂肪肝炎の鑑別マーカー及び当該マーカーを指標とした非アルコール性脂肪肝炎の診断方法
US20120264824A1 (en) * 2011-04-15 2012-10-18 Mochida Pharmaceutical Co., Ltd. Compositions and methods for treating non-alcoholic steatohepatitis
WO2014049131A1 (en) 2012-09-28 2014-04-03 Université d'Angers Accurate blood test for the non-invasive diagnosis of non-alcoholic steatohepatitis
WO2015192854A2 (en) 2014-06-16 2015-12-23 Aarhus Universitet Methods and tools for predicting steatohepatitis
CN104293908A (zh) 2014-06-18 2015-01-21 镇江市第三人民医院 用于检测非酒精性脂肪肝的血清miRNA标志物组合及应用
HUE056299T2 (hu) * 2015-09-14 2022-02-28 Genfit Eljárások nem-alkoholos steatohepatitis diagnosztizálására és kiértékelésére
US12104209B2 (en) * 2016-03-30 2024-10-01 Genfit Non-invasive diagnostic of non-alcoholic steatohepatitis

Also Published As

Publication number Publication date
EP3436600A1 (en) 2019-02-06
CN109072302B (zh) 2024-01-16
AU2017242818B2 (en) 2023-04-27
BR112018069560A2 (pt) 2019-01-29
MX2018011633A (es) 2019-01-10
EP3985126A1 (en) 2022-04-20
IL261814A (en) 2018-10-31
AU2017242818A1 (en) 2018-10-04
KR20180132092A (ko) 2018-12-11
JP7418959B2 (ja) 2024-01-22
PH12018502057A1 (en) 2019-06-24
SG11201808192RA (en) 2018-10-30
WO2017167934A1 (en) 2017-10-05
ZA201807083B (en) 2019-06-26
CN109072302A (zh) 2018-12-21
US20190352715A1 (en) 2019-11-21
CA3018133A1 (en) 2017-10-05
JP2022078250A (ja) 2022-05-24
EP3436600C0 (en) 2024-01-17
AU2023201802A1 (en) 2023-04-27
AU2023201802B2 (en) 2024-10-17
EP3436600B1 (en) 2024-01-17
JP2019511225A (ja) 2019-04-25
KR102646698B1 (ko) 2024-03-12
US12104209B2 (en) 2024-10-01

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