EA201890122A1 - Применение 2-(5s-метил-2-оксо-4r-фенилпирролидин-1-ил)ацетамида в лечении судорог - Google Patents

Применение 2-(5s-метил-2-оксо-4r-фенилпирролидин-1-ил)ацетамида в лечении судорог

Info

Publication number
EA201890122A1
EA201890122A1 EA201890122A EA201890122A EA201890122A1 EA 201890122 A1 EA201890122 A1 EA 201890122A1 EA 201890122 A EA201890122 A EA 201890122A EA 201890122 A EA201890122 A EA 201890122A EA 201890122 A1 EA201890122 A1 EA 201890122A1
Authority
EA
Eurasian Patent Office
Prior art keywords
acetamide
oxo
treatment
phenilpyrrolidin
methil
Prior art date
Application number
EA201890122A
Other languages
English (en)
Other versions
EA036085B1 (ru
Inventor
Лига Звейнице
Майя Дамброва
Байба Свалбе
Эдийс Ваверс
Иварс Калвинс
Григорийс Вейнбергс
Илмарс Стонанс
Илга Мисане
Максимс Ворона
Александрс Чернобровийс
Original Assignee
Латвийский Институт Органического Синтеза
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Латвийский Институт Органического Синтеза filed Critical Латвийский Институт Органического Синтеза
Publication of EA201890122A1 publication Critical patent/EA201890122A1/ru
Publication of EA036085B1 publication Critical patent/EA036085B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4015—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)

Abstract

Применение 2-(5S-метил-2-оксо-4R-фенилпирролидин-1-ил)ацетамида или его фармацевтически приемлемой соли в производстве лекарственного средства для профилактики и лечения судорог.
EA201890122A 2015-08-03 2016-08-02 Применение 2-(5s-метил-2-оксо-4r-фенил-пирролидин-1-ил)ацетамида в лечении судорог EA036085B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP15179448.4A EP3127539A1 (en) 2015-08-03 2015-08-03 Use of 2-(5s-methyl-2-oxo-4r-phenyl-pyrrolidin-1-yl)-acetamide in the treatment of seizures
PCT/IB2016/054641 WO2017021881A1 (en) 2015-08-03 2016-08-02 Use of 2-(5s-methyl-2-oxo-4r-phenyl-pyrrolidin-1-yl)-acetamide in the treatment of seizures

Publications (2)

Publication Number Publication Date
EA201890122A1 true EA201890122A1 (ru) 2018-05-31
EA036085B1 EA036085B1 (ru) 2020-09-24

Family

ID=53776429

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201890122A EA036085B1 (ru) 2015-08-03 2016-08-02 Применение 2-(5s-метил-2-оксо-4r-фенил-пирролидин-1-ил)ацетамида в лечении судорог

Country Status (11)

Country Link
US (1) US10105348B2 (ru)
EP (2) EP3127539A1 (ru)
JP (1) JP6470870B2 (ru)
CN (1) CN107921019B (ru)
BR (1) BR112018002138A2 (ru)
CA (1) CA2988045A1 (ru)
EA (1) EA036085B1 (ru)
MX (1) MX2018001355A (ru)
TW (1) TWI643617B (ru)
UA (1) UA120886C2 (ru)
WO (1) WO2017021881A1 (ru)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024049236A1 (ko) * 2022-08-31 2024-03-07 고려대학교 산학협력단 키랄 감마 락탐 유도체 또는 이의 약학적으로 허용가능한 염 및 이의 제조방법

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1731149A1 (en) * 2005-06-08 2006-12-13 Ucb S.A. Use of 2-oxo-1-pyrrolidone derivatives for the treatment of diseases characterized by progressive myoclonic epilepsy
LV13630B (en) * 2006-03-16 2007-12-20 Olainfarm As Method of preparation and use of pharmaceutically active n-carbamoylmethyl-4(r)-phenyl-2-pyrrolidinone
EP2358360B1 (en) * 2008-11-18 2016-09-14 UCB Biopharma SPRL Prolonged release formulations comprising an 2-oxo-1-pyrrolidine derivative
LV14346B (lv) * 2009-11-05 2011-07-20 Grindeks, A/S 2-(4-Fenil-5-metil-2-oksopirolidin-1-il)-acetamīda 4R,5S-enantiomērs ar nootropo aktivitāti
RU2480214C1 (ru) * 2011-09-22 2013-04-27 Валентина Ивановна Ахапкина Состав, обладающий модуляторной активностью с соразмерным влиянием, фармацевтическая субстанция (варианты), применение фармацевтической субстанции, фармацевтическая и парафармацевтическая композиция (варианты), способ получения фармацевтических составов

Also Published As

Publication number Publication date
UA120886C2 (uk) 2020-02-25
CN107921019A (zh) 2018-04-17
EA036085B1 (ru) 2020-09-24
CA2988045A1 (en) 2017-02-09
EP3331523B1 (en) 2021-10-13
EP3127539A1 (en) 2017-02-08
JP2018522019A (ja) 2018-08-09
WO2017021881A1 (en) 2017-02-09
US10105348B2 (en) 2018-10-23
JP6470870B2 (ja) 2019-02-13
MX2018001355A (es) 2018-05-22
US20180200227A1 (en) 2018-07-19
BR112018002138A2 (pt) 2018-09-11
CN107921019B (zh) 2021-03-05
TWI643617B (zh) 2018-12-11
EP3331523A1 (en) 2018-06-13
TW201709908A (zh) 2017-03-16

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