EA201500942A1 - ПРОТИВОВИРУСНЫЙ ИНДОЛО[2,3-b]ХИНОКСАЛИН - Google Patents

ПРОТИВОВИРУСНЫЙ ИНДОЛО[2,3-b]ХИНОКСАЛИН

Info

Publication number
EA201500942A1
EA201500942A1 EA201500942A EA201500942A EA201500942A1 EA 201500942 A1 EA201500942 A1 EA 201500942A1 EA 201500942 A EA201500942 A EA 201500942A EA 201500942 A EA201500942 A EA 201500942A EA 201500942 A1 EA201500942 A1 EA 201500942A1
Authority
EA
Eurasian Patent Office
Prior art keywords
virus
hinoxaline
indolo
compound
formula
Prior art date
Application number
EA201500942A
Other languages
English (en)
Inventor
Мохаммед Хомман
Нгарита Кинги
Ян Бергман
Роберт Берг
Original Assignee
Виронова Херпес Аб
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Виронова Херпес Аб filed Critical Виронова Херпес Аб
Publication of EA201500942A1 publication Critical patent/EA201500942A1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)

Abstract

Соединение формулы (I)применяемое при лечении инфекций вируса герпеса. Фармацевтическая композиция, содержащая соединение формулы (I).
EA201500942A 2013-03-15 2014-03-14 ПРОТИВОВИРУСНЫЙ ИНДОЛО[2,3-b]ХИНОКСАЛИН EA201500942A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361788867P 2013-03-15 2013-03-15
PCT/EP2014/055178 WO2014140321A1 (en) 2013-03-15 2014-03-14 Antiviral indolo[2,3-b]quinoxaline

Publications (1)

Publication Number Publication Date
EA201500942A1 true EA201500942A1 (ru) 2016-03-31

Family

ID=50280403

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201500942A EA201500942A1 (ru) 2013-03-15 2014-03-14 ПРОТИВОВИРУСНЫЙ ИНДОЛО[2,3-b]ХИНОКСАЛИН

Country Status (16)

Country Link
US (1) US20160031889A1 (ru)
EP (1) EP2970292A1 (ru)
JP (1) JP2016510798A (ru)
KR (1) KR20150130463A (ru)
CN (1) CN105102459A (ru)
AU (1) AU2014230133A1 (ru)
BR (1) BR112015022134A2 (ru)
CA (1) CA2904468A1 (ru)
CL (1) CL2015002730A1 (ru)
EA (1) EA201500942A1 (ru)
HK (1) HK1220196A1 (ru)
IL (1) IL241364A0 (ru)
MX (1) MX2015011387A (ru)
SG (1) SG11201507310VA (ru)
WO (1) WO2014140321A1 (ru)
ZA (1) ZA201507151B (ru)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4164649A1 (en) * 2020-06-10 2023-04-19 Cyxone AB New use of rabeximod
WO2022002898A1 (en) * 2020-06-29 2022-01-06 Vironova Medical Ab 6h-indolo(2,3-b)quinoxaline derivatives useful in therapy in particular in a virus infection
CA3191963A1 (en) 2020-09-21 2022-03-24 Jan Bergman Thionoester-derivative of rabeximod for the treatment of inflammatory and autoimmune disorders
US11643415B1 (en) * 2021-12-09 2023-05-09 Cyxone Ab Rabeximod compounds

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE527639C2 (sv) * 2004-06-17 2006-05-02 Oxypharma Ab Alkylsubstituerade indolokinoxaliner

Also Published As

Publication number Publication date
CN105102459A (zh) 2015-11-25
HK1220196A1 (zh) 2017-04-28
US20160031889A1 (en) 2016-02-04
KR20150130463A (ko) 2015-11-23
IL241364A0 (en) 2015-11-30
ZA201507151B (en) 2017-01-25
CA2904468A1 (en) 2014-09-18
EP2970292A1 (en) 2016-01-20
JP2016510798A (ja) 2016-04-11
MX2015011387A (es) 2016-06-10
AU2014230133A1 (en) 2015-11-05
SG11201507310VA (en) 2015-10-29
CL2015002730A1 (es) 2016-07-01
WO2014140321A1 (en) 2014-09-18
BR112015022134A2 (pt) 2017-07-18

Similar Documents

Publication Publication Date Title
CL2015003298A1 (es) Novedosas heteroarildihidropirimidinas unidas por puentes en 6 para el tratamiento y la profilaxis de infeccion por el virus de la hepatitis b
MX2019003525A (es) Moduladores alostericos de proteina nucleo de hepatitis b.
EA201791692A1 (ru) 4H-ПИРРОЛО[3,2-c]ПИРИДИН-4-ОНОВЫЕ ПРОИЗВОДНЫЕ
MX2016013689A (es) Compuestos 4-amino-imidazoquinolina.
EA202090547A2 (ru) Макроциклические деаза-оксипурины для лечения вирусных инфекций
CL2016000153A1 (es) Derivados de pirrolamida sustituidos con glioxamida y su uso como medicamentos para el tratamiento de la hepatitis b
CL2015003686A1 (es) Derivados de pirrolo[3,2-d]pirimidina para el tratamiento de infecciones víricas y otras enfermedades
DK3404031T3 (da) Thieno[3,2-d]pyrimidinderivater til behandling af virusinfektioner
CL2014002093A1 (es) Compuestos derivados piperidinopirimidinicos; composicion farmaceutica que los comprende; uso en el tratamiento de infecciones viricas.
EA201591524A1 (ru) Производные 2-аминопиримидина для лечения вирусных инфекций
DK3505173T3 (da) Pyrrolo[1,2-f][1,2,4]triaziner som er nyttige til behandling af infektioner med respiratorisk syncitialvirus
UA113651C2 (xx) Макроциклічні пурини для лікування вірусних інфекцій
EA201590931A1 (ru) Гетероциклические замещенные производные 2-амино-хиназолина для лечения вирусных инфекций
PH12017500393A1 (en) Pyrrolopyrimidines for use in influenza virus infection
CR20140231A (es) Derivados de ácido benzotiazol-6-il acético y su uso para tratar una infección por vih
CY1122805T1 (el) Ενωσεις και μεθοδοι για την αγωγη βακτηριακων λοιμωξεων
EA201691194A1 (ru) Стимуляторы ргц
UA115773C2 (uk) Пірольні сполуки, спосіб їх одержання та фармацевтична композиція, що їх містить (варіанти)
EA201500383A1 (ru) Производные 1,2,4-триазина для лечения вирусных инфекций
CL2015003019A1 (es) Derivados biaromáticos antibacterianos
CY1119619T1 (el) Παραγωγα πυριδιν-4-υλιου
CL2015002897A1 (es) Inhibidores de bace1
BR112017000246A2 (pt) composto, sal farmaceuticamente aceitável de um composto, composição farmacêutica, e, uso de um composto ou de um sal
MX2016007313A (es) Uso de derivados de bencimidazol-prolina.
MX2015013224A (es) Inhibidores macrociclicos y biciclicos del virus de la hepatitis c.