EA201490105A1 - Способы и композиции для диагностики и прогнозирования повреждений почек и почечной недостаточности - Google Patents
Способы и композиции для диагностики и прогнозирования повреждений почек и почечной недостаточностиInfo
- Publication number
- EA201490105A1 EA201490105A1 EA201490105A EA201490105A EA201490105A1 EA 201490105 A1 EA201490105 A1 EA 201490105A1 EA 201490105 A EA201490105 A EA 201490105A EA 201490105 A EA201490105 A EA 201490105A EA 201490105 A1 EA201490105 A1 EA 201490105A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- compositions
- methods
- kidney damage
- prediction
- diagnosis
- Prior art date
Links
- 230000006378 damage Effects 0.000 title abstract 2
- 210000003734 kidney Anatomy 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 208000001647 Renal Insufficiency Diseases 0.000 title 1
- 238000003745 diagnosis Methods 0.000 title 1
- 201000006370 kidney failure Diseases 0.000 title 1
- 206010061481 Renal injury Diseases 0.000 abstract 2
- 101710087237 Whey acidic protein Proteins 0.000 abstract 2
- 208000037806 kidney injury Diseases 0.000 abstract 2
- 108010045100 HSP27 Heat-Shock Proteins Proteins 0.000 abstract 1
- 102000005623 HSP27 Heat-Shock Proteins Human genes 0.000 abstract 1
- 102000002812 Heat-Shock Proteins Human genes 0.000 abstract 1
- 108010004889 Heat-Shock Proteins Proteins 0.000 abstract 1
- 101000595923 Homo sapiens Placenta growth factor Proteins 0.000 abstract 1
- 102100035194 Placenta growth factor Human genes 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 238000003556 assay Methods 0.000 abstract 1
- 239000000104 diagnostic biomarker Substances 0.000 abstract 1
- 239000003550 marker Substances 0.000 abstract 1
- 230000002438 mitochondrial effect Effects 0.000 abstract 1
- 238000012544 monitoring process Methods 0.000 abstract 1
- 239000000092 prognostic biomarker Substances 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 238000011269 treatment regimen Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54306—Solid-phase reaction mechanisms
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/475—Assays involving growth factors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/575—Hormones
- G01N2333/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/81—Protease inhibitors
- G01N2333/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/34—Genitourinary disorders
- G01N2800/347—Renal failures; Glomerular diseases; Tubulointerstitial diseases, e.g. nephritic syndrome, glomerulonephritis; Renovascular diseases, e.g. renal artery occlusion, nephropathy
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/56—Staging of a disease; Further complications associated with the disease
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Cell Biology (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161506038P | 2011-07-09 | 2011-07-09 | |
| PCT/US2012/045583 WO2013009573A1 (en) | 2011-07-09 | 2012-07-05 | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EA201490105A1 true EA201490105A1 (ru) | 2014-07-30 |
Family
ID=47506416
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA201490105A EA201490105A1 (ru) | 2011-07-09 | 2012-07-05 | Способы и композиции для диагностики и прогнозирования повреждений почек и почечной недостаточности |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US20140171522A1 (enExample) |
| EP (1) | EP2729803A4 (enExample) |
| JP (1) | JP2014521088A (enExample) |
| CN (1) | CN103858008B (enExample) |
| AU (1) | AU2012282918A1 (enExample) |
| CA (1) | CA2841880A1 (enExample) |
| EA (1) | EA201490105A1 (enExample) |
| MX (1) | MX2014000283A (enExample) |
| WO (1) | WO2013009573A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014120569A1 (en) * | 2013-01-25 | 2014-08-07 | Beth Israel Deaconess Medical Center, Inc. | Methods and compositions for human epididymis protein-4 (he4) |
| US10130950B2 (en) | 2013-11-27 | 2018-11-20 | Bio-Rad Laboratories, Inc. | Microfluidic droplet packing |
| CN104045453B (zh) * | 2014-06-11 | 2016-08-24 | 句容市鑫诚果业家庭农场 | 一种石榴专用有机肥料及其制备方法 |
| CN106536709A (zh) | 2014-06-16 | 2017-03-22 | 基纽拜奥股份有限公司 | 尺寸交替的注入到液滴中以促进分选 |
| CN104062294A (zh) * | 2014-07-11 | 2014-09-24 | 青岛千士医疗科技有限公司 | 一种支气管/肺上皮细胞线粒体损伤的检测方法 |
| CN104166003B (zh) * | 2014-08-06 | 2016-06-08 | 中国人民解放军第二军医大学 | 人附睾蛋白4在制备系统性红斑狼疮性肾病诊断试剂或试剂盒中的应用 |
| WO2016130802A1 (en) * | 2015-02-11 | 2016-08-18 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| TW201827070A (zh) * | 2016-12-19 | 2018-08-01 | 康鶴生醫科技股份有限公司 | 合成多肽、含該多肽的組合物、由其產生的抗體及其用途 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU7347300A (en) * | 1999-09-02 | 2001-03-26 | Gene Logic, Inc. | Modulation of he4 in inflammatory and renal diseases |
| CN1791797A (zh) * | 2003-03-27 | 2006-06-21 | 儿童医院医疗中心 | 用于检测肾小管细胞损伤的早发的方法和试剂盒 |
| US7588892B2 (en) * | 2004-07-19 | 2009-09-15 | Entelos, Inc. | Reagent sets and gene signatures for renal tubule injury |
| US20070087387A1 (en) * | 2005-04-21 | 2007-04-19 | Prasad Devarajan | Method for the Early Detection of Renal Disease Using Proteomics |
| EP2095107B1 (en) * | 2006-11-14 | 2014-07-02 | Alere San Diego, Inc. | Methods for risk assignment |
| KR20100015438A (ko) * | 2007-03-09 | 2010-02-12 | 트리패스 이미징, 인코포레이티드 | Ｈｅ4 모노클로날 항체 및 이의 사용 방법 |
| EP2479568B1 (en) * | 2007-03-26 | 2015-01-07 | Novartis AG | Predictive renal safety biomarkers and biomarker signatures to monitor kidney function |
| KR20100122495A (ko) * | 2008-02-29 | 2010-11-22 | 고쿠리츠 다이가쿠 호우징 나고야 다이가쿠 | 급성 신장 장해 및 예후 추정용 바이오마커 및 그 용도 |
| CN102016552A (zh) * | 2008-03-05 | 2011-04-13 | 神谷来克斯公司 | 用于分子的高灵敏性检测的方法和组合物 |
| CN102089658A (zh) * | 2008-06-04 | 2011-06-08 | 普罗迪奥塞斯股份公司 | 用于体外测试化学物质的发育毒性和胚胎毒性的蛋白生物标志物 |
| NZ610356A (en) * | 2008-08-28 | 2015-03-27 | Astute Medical Inc | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| ES2528799T3 (es) * | 2008-11-22 | 2015-02-12 | Astute Medical, Inc. | Métodos para el pronóstico de insuficiencia renal aguda |
| JP5763098B2 (ja) * | 2009-12-20 | 2015-08-12 | アスチュート メディカル，インコーポレイテッド | 腎損傷および腎不全の診断および予後診断のための方法ならびに組成物 |
| US20120329071A1 (en) * | 2010-03-05 | 2012-12-27 | Mark Chance | Protein biomarkers and therapeutic targets for renal disorders |
| EP2646822B1 (en) * | 2010-11-29 | 2017-11-01 | Alere San Diego, Inc. | Methods for diagnosis and risk prediction in heart failure |
| WO2013006629A1 (en) * | 2011-07-06 | 2013-01-10 | Alere San Diego Inc. | Methods and compositions for assigning likelihood of acute kidney injury progression |
-
2012
- 2012-07-05 CA CA2841880A patent/CA2841880A1/en not_active Abandoned
- 2012-07-05 MX MX2014000283A patent/MX2014000283A/es not_active Application Discontinuation
- 2012-07-05 AU AU2012282918A patent/AU2012282918A1/en not_active Abandoned
- 2012-07-05 JP JP2014520221A patent/JP2014521088A/ja active Pending
- 2012-07-05 US US14/131,678 patent/US20140171522A1/en not_active Abandoned
- 2012-07-05 EP EP12810709.1A patent/EP2729803A4/en not_active Withdrawn
- 2012-07-05 WO PCT/US2012/045583 patent/WO2013009573A1/en not_active Ceased
- 2012-07-05 EA EA201490105A patent/EA201490105A1/ru unknown
- 2012-07-05 CN CN201280039959.5A patent/CN103858008B/zh not_active Expired - Fee Related
-
2015
- 2015-12-09 US US14/964,410 patent/US20160097779A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2013009573A1 (en) | 2013-01-17 |
| CN103858008B (zh) | 2017-03-01 |
| JP2014521088A (ja) | 2014-08-25 |
| EP2729803A1 (en) | 2014-05-14 |
| AU2012282918A1 (en) | 2014-02-06 |
| US20140171522A1 (en) | 2014-06-19 |
| EP2729803A4 (en) | 2015-08-05 |
| US20160097779A1 (en) | 2016-04-07 |
| CN103858008A (zh) | 2014-06-11 |
| CA2841880A1 (en) | 2013-01-17 |
| MX2014000283A (es) | 2014-05-01 |
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