EA201401057A1 - Method of treating epithelial neoplasms - Google Patents
Method of treating epithelial neoplasmsInfo
- Publication number
- EA201401057A1 EA201401057A1 EA201401057A EA201401057A EA201401057A1 EA 201401057 A1 EA201401057 A1 EA 201401057A1 EA 201401057 A EA201401057 A EA 201401057A EA 201401057 A EA201401057 A EA 201401057A EA 201401057 A1 EA201401057 A1 EA 201401057A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- procedural
- fluorescence
- photosensitizer
- post
- epithelial neoplasms
- Prior art date
Links
Landscapes
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Radiation-Therapy Devices (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Изобретение относится к медицине, а именно к разделу онкология, и предназначено для эффективного лечения предраковых и злокачественных новообразований, предпочтительно эпителия тела человека. Задачей настоящего изобретения является создание индивидуализированного эффективного способа лечения эпителиальных новообразований наружной локализации, в котором по сравнению со стандартными и перечисленными выше методами минимизирован риск осложнений, рецидивов и возможность ухудшения качества жизни пациентов. Способ лечения эпителиальных новообразований включает в себя введение фотосенсибилизатора, диагностическое предпроцедурное флуоресцентное обследование через 2,5-4 ч после введения фотосенсибилизатора с определением операционного поля в виде патологически измененной области, с предпроцедурным определением уровней флуоресценции и терапевтическое воздействие на таким образом определенное операционное поле оптическим излучением с длиной волны, соответствующей полосе поглощения фотосенсибилизатора, и экспозиционными параметрами, достаточными для достижения некроза пораженных тканей, контрольное постпроцедурное флуоресцентное обследование ранее определенного операционного поля с определением постпроцедурного уровня флуоресценции. В заявленном способе как диагностическое предпроцедурное и постпроцедурное флуоресцентное обследования, так и терапевтическое воздействие на патологически измененную область оптическим излучением осуществляют в рамках одной процедуры с использованием однократного введения фотосенсибилизатора на основе хлорина е6.The invention relates to medicine, namely to the section oncology, and is intended for the effective treatment of precancerous and malignant tumors, preferably the epithelium of the human body. The present invention is the creation of an individualized effective method for the treatment of epithelial neoplasms of external localization, in which, compared to the standard methods listed above, the risk of complications, relapses and the possibility of deterioration in the quality of life of patients is minimized. A method of treating epithelial neoplasms includes the introduction of a photosensitizer, diagnostic pre-procedural fluorescence examination 2.5-4 hours after the photosensitizer is injected, determining the operative field in the form of a pathologically altered area, with pre-procedural determination of fluorescence levels and the therapeutic effect on the defined operational field by optical radiation with a wavelength corresponding to the absorption band of the photosensitizer, and exposure parameters, to sufficient to achieve necrosis of the affected tissues, control post-procedural fluorescence examination of a previously defined surgical field with the determination of post-procedural fluorescence. In the proposed method, both a diagnostic pre-procedure and post-procedural fluorescence examinations, and a therapeutic effect on the pathologically altered area by optical radiation are carried out within the same procedure using a single injection of a chlorine e6 photosensitizer.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EA201401057A EA030166B1 (en) | 2014-08-29 | 2014-08-29 | Method for treatment of epithelial neoplasms |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EA201401057A EA030166B1 (en) | 2014-08-29 | 2014-08-29 | Method for treatment of epithelial neoplasms |
Publications (2)
Publication Number | Publication Date |
---|---|
EA201401057A1 true EA201401057A1 (en) | 2016-03-31 |
EA030166B1 EA030166B1 (en) | 2018-06-29 |
Family
ID=58225007
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA201401057A EA030166B1 (en) | 2014-08-29 | 2014-08-29 | Method for treatment of epithelial neoplasms |
Country Status (1)
Country | Link |
---|---|
EA (1) | EA030166B1 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2665115C1 (en) * | 2017-03-20 | 2018-08-28 | Виолета Александровна Пурцхванидзе | Method for the complex treatment of kraurosis and leukoplakia of vulva |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2204426C1 (en) * | 2001-11-20 | 2003-05-20 | Московский научно-исследовательский онкологический институт им. П.А. Герцена | Photodynamic method for diagnosing and treating the cases of patients for primary multiple skin carcinoma |
RU2284839C1 (en) * | 2005-02-24 | 2006-10-10 | Московская городская онкологическая больница №62 | Method for photodynamic therapy of intraepithelial vulval dysplasia |
RU2448745C2 (en) * | 2010-05-31 | 2012-04-27 | Олег Феликсович Каган | Method of treating superficial urinary bladder cancer |
-
2014
- 2014-08-29 EA EA201401057A patent/EA030166B1/en not_active IP Right Cessation
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2665115C1 (en) * | 2017-03-20 | 2018-08-28 | Виолета Александровна Пурцхванидзе | Method for the complex treatment of kraurosis and leukoplakia of vulva |
Also Published As
Publication number | Publication date |
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EA030166B1 (en) | 2018-06-29 |
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MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
Designated state(s): AM AZ KG TJ TM |
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MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
Designated state(s): BY |
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MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
Designated state(s): KZ RU |