EA201391605A1 - Способы очистки вирусов с использованием гельпроникающей хроматографии - Google Patents

Способы очистки вирусов с использованием гельпроникающей хроматографии

Info

Publication number
EA201391605A1
EA201391605A1 EA201391605A EA201391605A EA201391605A1 EA 201391605 A1 EA201391605 A1 EA 201391605A1 EA 201391605 A EA201391605 A EA 201391605A EA 201391605 A EA201391605 A EA 201391605A EA 201391605 A1 EA201391605 A1 EA 201391605A1
Authority
EA
Eurasian Patent Office
Prior art keywords
methods
chromatography
viruses
gelproducting
gel permeation
Prior art date
Application number
EA201391605A
Other languages
English (en)
Russian (ru)
Inventor
Мэттью С. Коффи
Эллисон Хагерман
Роксна Кападиа
Сара Серл
Original Assignee
Онколитикс Байотек Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Онколитикс Байотек Инк. filed Critical Онколитикс Байотек Инк.
Publication of EA201391605A1 publication Critical patent/EA201391605A1/ru

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/26Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/34Size-selective separation, e.g. size-exclusion chromatography; Gel filtration; Permeation
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/42Selective adsorption, e.g. chromatography characterised by the development mode, e.g. by displacement or by elution
    • B01D15/424Elution mode
    • B01D15/426Specific type of solvent
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/02Separating microorganisms from their culture media
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011Details
    • C12N2720/12011Reoviridae
    • C12N2720/12051Methods of production or purification of viral material

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
EA201391605A 2011-04-29 2012-04-27 Способы очистки вирусов с использованием гельпроникающей хроматографии EA201391605A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161480561P 2011-04-29 2011-04-29
PCT/CA2012/000406 WO2012145837A1 (en) 2011-04-29 2012-04-27 Methods of purifying viruses using gel permeation chromatography

Publications (1)

Publication Number Publication Date
EA201391605A1 true EA201391605A1 (ru) 2014-02-28

Family

ID=47067091

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201391605A EA201391605A1 (ru) 2011-04-29 2012-04-27 Способы очистки вирусов с использованием гельпроникающей хроматографии

Country Status (15)

Country Link
US (1) US20120273424A1 (https=)
EP (1) EP2702147B1 (https=)
JP (1) JP6029651B2 (https=)
KR (2) KR20140024406A (https=)
CN (1) CN103492557B (https=)
AU (1) AU2012248082B2 (https=)
CA (1) CA2832367A1 (https=)
DK (1) DK2702147T3 (https=)
EA (1) EA201391605A1 (https=)
ES (1) ES2822199T3 (https=)
IL (1) IL228491A (https=)
MX (1) MX337348B (https=)
SG (1) SG194449A1 (https=)
TW (1) TW201307561A (https=)
WO (1) WO2012145837A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2646051A4 (en) * 2010-12-02 2014-05-28 Oncolytics Biotech Inc FORMULATIONS OF LIQUID VIRUSES
MX349294B (es) 2010-12-02 2017-07-21 Oncolytics Biotech Inc Formulaciones virales liofilizadas.
RS57864B1 (sr) * 2013-06-17 2018-12-31 De Staat Der Nederlanden Vert Door De Minister Van Vws Ministerie Van Volksgezondheid Welzijn En Spo Postupci za sprečavanje agregacije virusnih komponenti
US11999975B2 (en) 2018-07-04 2024-06-04 Probiogen Ag Method for purifying an enveloped virus
CN111812313B (zh) * 2020-06-22 2021-10-08 北京生物制品研究所有限责任公司 铝佐剂吸附型新型冠状病毒灭活疫苗中抗原的解离方法
CN114544815B (zh) * 2022-03-01 2023-10-27 中牧实业股份有限公司 一种山羊痘病毒的定量检测方法
CN116718524B (zh) * 2023-06-26 2025-11-07 西安交通大学 一种基于细胞膜色谱技术的病毒颗粒检测方法
HUP2400154A1 (hu) * 2024-02-29 2025-09-28 Pecsi Tudomanyegyetem Elúciós oldat és tisztítási eljárás

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5096885A (en) * 1988-04-15 1992-03-17 Genentech, Inc. Human growth hormone formulation
EP0410207B1 (en) * 1989-07-24 1997-01-22 Bayer Corporation Stabilization of highly purified proteins
ATE328068T1 (de) * 1994-05-16 2006-06-15 Merck & Co Inc Papillomavirus vakzine
IL137510A0 (en) * 1998-02-17 2001-07-24 Schering Corp Compositions comprising viruses and methods for concentrating virus preparations
IL157304A0 (en) 2001-03-16 2004-02-19 Oncolytics Biotech Inc Method of extracting virus from cell culture
DE60327069D1 (de) * 2002-04-30 2009-05-20 Oncolytics Biotech Inc Verbesserte reinigungsmethode für viren
US7901921B2 (en) 2004-10-22 2011-03-08 Oncolytics Biotech Inc. Viral purification methods
EP1878791A1 (en) * 2006-07-11 2008-01-16 Bia Separations D.O.O. Method for influenza virus purification
DK2055311T3 (en) * 2006-08-07 2017-07-24 The Chemo-Sero-Therapeutic Res Inst METHOD OF MANUFACTURING LIVING COPPER VACCINE
SG191602A1 (en) * 2007-03-12 2013-07-31 Oncolytics Biotech Inc Reoviruses having modified sequences
JP4932940B2 (ja) * 2007-11-12 2012-05-16 セラクローン サイエンシーズ, インコーポレイテッド インフルエンザの治療および診断のための組成物および方法
US8227577B2 (en) * 2007-12-21 2012-07-24 Hoffman-La Roche Inc. Bivalent, bispecific antibodies
MX349294B (es) * 2010-12-02 2017-07-21 Oncolytics Biotech Inc Formulaciones virales liofilizadas.
EP2646051A4 (en) * 2010-12-02 2014-05-28 Oncolytics Biotech Inc FORMULATIONS OF LIQUID VIRUSES

Also Published As

Publication number Publication date
MX337348B (es) 2016-02-29
EP2702147A1 (en) 2014-03-05
IL228491A (en) 2017-05-29
JP6029651B2 (ja) 2016-11-24
JP2014516515A (ja) 2014-07-17
CA2832367A1 (en) 2012-11-01
KR20140024406A (ko) 2014-02-28
EP2702147A4 (en) 2014-11-05
CN103492557A (zh) 2014-01-01
AU2012248082B2 (en) 2015-08-20
AU2012248082A1 (en) 2013-05-09
ES2822199T3 (es) 2021-04-29
KR102151890B1 (ko) 2020-09-03
DK2702147T3 (da) 2020-09-28
US20120273424A1 (en) 2012-11-01
MX2013012627A (es) 2014-05-13
SG194449A1 (en) 2013-12-30
EP2702147B1 (en) 2020-07-15
IL228491A0 (en) 2013-12-31
TW201307561A (zh) 2013-02-16
KR20190026059A (ko) 2019-03-12
WO2012145837A1 (en) 2012-11-01
CN103492557B (zh) 2015-07-29

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