EA201391605A1 - Способы очистки вирусов с использованием гельпроникающей хроматографии - Google Patents

Способы очистки вирусов с использованием гельпроникающей хроматографии

Info

Publication number
EA201391605A1
EA201391605A1 EA201391605A EA201391605A EA201391605A1 EA 201391605 A1 EA201391605 A1 EA 201391605A1 EA 201391605 A EA201391605 A EA 201391605A EA 201391605 A EA201391605 A EA 201391605A EA 201391605 A1 EA201391605 A1 EA 201391605A1
Authority
EA
Eurasian Patent Office
Prior art keywords
methods
chromatography
viruses
gelproducting
gel permeation
Prior art date
Application number
EA201391605A
Other languages
English (en)
Russian (ru)
Inventor
Мэттью С. Коффи
Эллисон Хагерман
Роксна Кападиа
Сара Серл
Original Assignee
Онколитикс Байотек Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Онколитикс Байотек Инк. filed Critical Онколитикс Байотек Инк.
Publication of EA201391605A1 publication Critical patent/EA201391605A1/ru

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/26Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/34Size-selective separation, e.g. size-exclusion chromatography; Gel filtration; Permeation
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/42Selective adsorption, e.g. chromatography characterised by the development mode, e.g. by displacement or by elution
    • B01D15/424Elution mode
    • B01D15/426Specific type of solvent
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/02Separating microorganisms from their culture media
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011Details
    • C12N2720/12011Reoviridae
    • C12N2720/12051Methods of production or purification of viral material

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Medicinal Preparation (AREA)
EA201391605A 2011-04-29 2012-04-27 Способы очистки вирусов с использованием гельпроникающей хроматографии EA201391605A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161480561P 2011-04-29 2011-04-29
PCT/CA2012/000406 WO2012145837A1 (en) 2011-04-29 2012-04-27 Methods of purifying viruses using gel permeation chromatography

Publications (1)

Publication Number Publication Date
EA201391605A1 true EA201391605A1 (ru) 2014-02-28

Family

ID=47067091

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201391605A EA201391605A1 (ru) 2011-04-29 2012-04-27 Способы очистки вирусов с использованием гельпроникающей хроматографии

Country Status (15)

Country Link
US (1) US20120273424A1 (https=)
EP (1) EP2702147B1 (https=)
JP (1) JP6029651B2 (https=)
KR (2) KR20140024406A (https=)
CN (1) CN103492557B (https=)
AU (1) AU2012248082B2 (https=)
CA (1) CA2832367A1 (https=)
DK (1) DK2702147T3 (https=)
EA (1) EA201391605A1 (https=)
ES (1) ES2822199T3 (https=)
IL (1) IL228491A (https=)
MX (1) MX337348B (https=)
SG (1) SG194449A1 (https=)
TW (1) TW201307561A (https=)
WO (1) WO2012145837A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2011336413B2 (en) * 2010-12-02 2015-01-22 Oncolytics Biotech Inc. Liquid viral formulations
MX349294B (es) 2010-12-02 2017-07-21 Oncolytics Biotech Inc Formulaciones virales liofilizadas.
BR112015031541A2 (pt) 2013-06-17 2017-07-25 De Staat Der Nederlanden Vert Door De Mini Van Vws Miniie Van Volksgezondheid Welzijn En Sport métodos para o impedimento da agregação de componentes virais
US11999975B2 (en) 2018-07-04 2024-06-04 Probiogen Ag Method for purifying an enveloped virus
CN111812313B (zh) * 2020-06-22 2021-10-08 北京生物制品研究所有限责任公司 铝佐剂吸附型新型冠状病毒灭活疫苗中抗原的解离方法
CN114544815B (zh) * 2022-03-01 2023-10-27 中牧实业股份有限公司 一种山羊痘病毒的定量检测方法
CN116718524B (zh) * 2023-06-26 2025-11-07 西安交通大学 一种基于细胞膜色谱技术的病毒颗粒检测方法
HUP2400154A1 (hu) * 2024-02-29 2025-09-28 Pecsi Tudomanyegyetem Elúciós oldat és tisztítási eljárás

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5096885A (en) * 1988-04-15 1992-03-17 Genentech, Inc. Human growth hormone formulation
DE69029765T2 (de) * 1989-07-24 1997-05-15 Bayer Ag Stabilisierung von hochgereinigten Proteinen
JP3863559B2 (ja) * 1994-05-16 2006-12-27 メルク エンド カンパニー インコーポレーテッド 乳頭腫ウィルスワクチン
KR100912362B1 (ko) * 1998-02-17 2009-08-19 쉐링 코포레이션 바이러스 제제의 정제방법
DK2253701T3 (da) 2001-03-16 2014-10-20 Oncolytics Biotech Inc Fremgangsmåde til ekstraktion af en virus fra en cellekultur
CA2482512C (en) * 2002-04-30 2011-09-20 Oncolytics Biotech Inc. Improved viral purification methods
US7901921B2 (en) * 2004-10-22 2011-03-08 Oncolytics Biotech Inc. Viral purification methods
EP1878791A1 (en) * 2006-07-11 2008-01-16 Bia Separations D.O.O. Method for influenza virus purification
EP2055311B1 (en) * 2006-08-07 2017-06-21 The Chemo-Sero-Therapeutic Research Institute Process for preparing live smallpox vaccine
JP5577103B2 (ja) * 2007-03-12 2014-08-20 オンコリティクス バイオテク,インコーポレーテッド 改変配列を有するレオウイルス
NZ585500A (en) * 2007-11-12 2012-06-29 Theraclone Sciences Inc Antibodies which bind to an epitope in the extracellular domain of the matrix 2 ectodomain polypeptide of an influenza virus
US8227577B2 (en) * 2007-12-21 2012-07-24 Hoffman-La Roche Inc. Bivalent, bispecific antibodies
MX349294B (es) * 2010-12-02 2017-07-21 Oncolytics Biotech Inc Formulaciones virales liofilizadas.
AU2011336413B2 (en) * 2010-12-02 2015-01-22 Oncolytics Biotech Inc. Liquid viral formulations

Also Published As

Publication number Publication date
KR20190026059A (ko) 2019-03-12
MX2013012627A (es) 2014-05-13
JP2014516515A (ja) 2014-07-17
KR102151890B1 (ko) 2020-09-03
IL228491A (en) 2017-05-29
EP2702147B1 (en) 2020-07-15
SG194449A1 (en) 2013-12-30
AU2012248082A1 (en) 2013-05-09
IL228491A0 (en) 2013-12-31
AU2012248082B2 (en) 2015-08-20
WO2012145837A1 (en) 2012-11-01
CN103492557A (zh) 2014-01-01
ES2822199T3 (es) 2021-04-29
MX337348B (es) 2016-02-29
KR20140024406A (ko) 2014-02-28
US20120273424A1 (en) 2012-11-01
EP2702147A1 (en) 2014-03-05
EP2702147A4 (en) 2014-11-05
CN103492557B (zh) 2015-07-29
TW201307561A (zh) 2013-02-16
CA2832367A1 (en) 2012-11-01
DK2702147T3 (da) 2020-09-28
JP6029651B2 (ja) 2016-11-24

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