EA201370006A1 - Местная фармацевтическая композиция, содержащая флурбипрофен - Google Patents

Местная фармацевтическая композиция, содержащая флурбипрофен

Info

Publication number
EA201370006A1
EA201370006A1 EA201370006A EA201370006A EA201370006A1 EA 201370006 A1 EA201370006 A1 EA 201370006A1 EA 201370006 A EA201370006 A EA 201370006A EA 201370006 A EA201370006 A EA 201370006A EA 201370006 A1 EA201370006 A1 EA 201370006A1
Authority
EA
Eurasian Patent Office
Prior art keywords
flurbiprophen
pharmaceutical composition
composition containing
local pharmaceutical
pain
Prior art date
Application number
EA201370006A
Other languages
English (en)
Inventor
Корал Эмбыл
Рей Фигероа
Original Assignee
Эдко Пазарлама Танитим Тиджарет Лимитед Ширкети
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Эдко Пазарлама Танитим Тиджарет Лимитед Ширкети filed Critical Эдко Пазарлама Танитим Тиджарет Лимитед Ширкети
Publication of EA201370006A1 publication Critical patent/EA201370006A1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • A61K31/245—Amino benzoic acid types, e.g. procaine, novocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Anesthesiology (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

Изобретение обеспечивает местные фармацевтические композиции, содержащие флурбипрофен или его фармацевтически приемлемое производное в комбинации с солюбилизирующей системой, которая содержит по меньшей мере один простой эфир гликоля и по меньшей мере один сложный эфир гликоля. Они являются приемлемыми для лечения любого состояния, ассоциированного с болью, воспалением и/или тугоподвижностью, например подкожной болью в суставах или мягкой ткани.
EA201370006A 2010-06-29 2011-06-28 Местная фармацевтическая композиция, содержащая флурбипрофен EA201370006A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1010954.4A GB201010954D0 (en) 2010-06-29 2010-06-29 Compositions
PCT/GB2011/051220 WO2012001403A1 (en) 2010-06-29 2011-06-28 Topical pharmaceutical composition comprising flurbiprofen

Publications (1)

Publication Number Publication Date
EA201370006A1 true EA201370006A1 (ru) 2013-05-30

Family

ID=42583177

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201370006A EA201370006A1 (ru) 2010-06-29 2011-06-28 Местная фармацевтическая композиция, содержащая флурбипрофен

Country Status (11)

Country Link
US (1) US20130143831A1 (ru)
EP (1) EP2588100A1 (ru)
KR (1) KR20130139842A (ru)
CN (1) CN103079552A (ru)
AR (1) AR082030A1 (ru)
BR (1) BR112012033590A2 (ru)
EA (1) EA201370006A1 (ru)
GB (1) GB201010954D0 (ru)
MX (1) MX2013000256A (ru)
SG (1) SG186866A1 (ru)
WO (1) WO2012001403A1 (ru)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI433674B (zh) 2006-12-28 2014-04-11 Infinity Discovery Inc 環杷明（ｃｙｃｌｏｐａｍｉｎｅ）類似物類
CA2769795C (en) 2009-08-05 2020-01-07 Infinity Pharmaceuticals, Inc. Enzymatic transamination of cyclopamine analogs
US9376447B2 (en) 2010-09-14 2016-06-28 Infinity Pharmaceuticals, Inc. Transfer hydrogenation of cyclopamine analogs
WO2013138075A1 (en) * 2012-03-14 2013-09-19 Novan, Inc. Nitric oxide releasing pharmaceutical compositions
BR112016002387B1 (pt) 2013-08-08 2019-05-21 Novan, Inc. Composições farmacêuticas tópicas, e método para seu armazenamento
JP6463745B2 (ja) * 2013-10-11 2019-02-06 ベータ ファーマシューティカルズ カンパニー リミテッド イコチニブ含有皮膚外用医薬組成物及びその応用
JP6831704B2 (ja) * 2014-06-18 2021-02-17 エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト 非イオン界面活性剤を含む新規の薬学的組成物
CA2919733A1 (en) 2014-08-08 2016-02-08 Novan, Inc. Topical compositions and methods of using the same
MX371533B (es) * 2014-10-07 2020-01-30 Taisho Pharmaceutical Co Ltd Composicion de preparacion externa que contiene s-flurbiprofeno.
AU2016271468B2 (en) 2015-06-04 2020-01-02 Sol-Gel Technologies Ltd. Topical formulations for delivery of hedgehog inhibitor compounds and use thereof
US10912743B2 (en) 2016-03-02 2021-02-09 Novan, Inc. Compositions for treating inflammation and methods of treating the same
KR20190037229A (ko) * 2016-06-13 2019-04-05 바이옴 테라퓨틱스 리미티드 상승효과적 항진균 조성물 및 그의 방법
PT3471702T (pt) * 2016-06-20 2022-03-17 Capretto Ehf Formulação termoestável de substâncias biologicamente ativas
EP3758679A4 (en) 2018-03-01 2021-12-15 Novan, Inc. NITRIC OXIDE RELEASING SUPPOSITORIES AND THEIR METHODS OF USE

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS52156913A (en) 1976-06-21 1977-12-27 Toko Yakuhin Kogyo Kk Production of injectionable medicine
JPS56154413A (en) 1980-04-30 1981-11-30 Riide Chem Kk Anti-inflammatory analgesic for external use
GB2075837B (en) 1980-05-14 1984-03-14 Hisamitsu Pharmaceutical Co Topical pharmaceutical gel containing anti-inflammatory analgesic agents
JPS5829706A (ja) * 1981-08-14 1983-02-22 Toko Yakuhin Kogyo Kk 消炎鎮痛外用剤
JPS59222409A (ja) 1983-06-01 1984-12-14 Nippon Redarii Kk 消炎鎮痛ゲル軟膏剤
JPH08509222A (ja) * 1993-04-22 1996-10-01 ミネソタ マイニング アンド マニュファクチャリング カンパニー 経皮抗炎症性組成物
US5807568A (en) 1994-12-27 1998-09-15 Mcneil-Ppc, Inc. Enhanced delivery of topical compositions containing flurbiprofen
US6248363B1 (en) * 1999-11-23 2001-06-19 Lipocine, Inc. Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
US20030143165A1 (en) * 2002-01-25 2003-07-31 Allan Evans NSAID-containing topical formulations that demonstrate chemopreventive activity
TR200703092A1 (tr) * 2007-05-08 2008-12-22 SANOVEL �LA� SAN. VE TiC. A.�. Flurbiprofen ve kas gevşetici kombinasyonları

Also Published As

Publication number Publication date
CN103079552A (zh) 2013-05-01
KR20130139842A (ko) 2013-12-23
AR082030A1 (es) 2012-11-07
US20130143831A1 (en) 2013-06-06
SG186866A1 (en) 2013-02-28
WO2012001403A1 (en) 2012-01-05
MX2013000256A (es) 2013-05-30
BR112012033590A2 (pt) 2016-11-29
EP2588100A1 (en) 2013-05-08
GB201010954D0 (en) 2010-08-11

Similar Documents

Publication Publication Date Title
EA201370006A1 (ru) Местная фармацевтическая композиция, содержащая флурбипрофен
CY1119616T1 (el) Συζευγματα ανθρωπινου αντισωματος-φαρμακου κατα του ιστικου παραγοντα
CY1119007T1 (el) Συνθεσεις και μεθοδοι αγωγης πνευμονικης υπερτασης
CL2013001654A1 (es) Compuestos derivados de 6-amino-2-fenilamino-1h-bencimidazol-5-carboxamida; composicion farmaceutica; y su uso en el tratamiento y/o prevencion de las enfermedades inflamatorias y/o afecciones asociadas, en particular el dolor.
MY187047A (en) Selective pyy compounds and uses thereof
EA201390803A1 (ru) Ингибиторы бромодомена и их применение
CL2013000304A1 (es) Compuestos derivados de 2-arilamino-bencimidazoles inhibidores de prostaglandina e2 (mpges-1); composicion farmaceutica que los comprende; compuestos intermediarios; uso en el tratamiento de enfermedades inflamatorias y/o afecciones asociadas, en particular el dolor.
BR112015023391A2 (pt) formulações compreendendo conjugado droga-anticorpo anti-egfr
EA200802166A1 (ru) Стабильная фармацевтическая композиция с защитным действием от раздражения (варианты), способ ее получения и способ лечения кальций-миметиком с ее помощью
CY1117237T1 (el) Συνθεσεις σταθερων τιακουμυκινων
EA201290171A1 (ru) Вводимые перорально кортикостероидные композиции
CR11731A (es) Composiciones y procedimientos para su preparación y uso
CR20110596A (es) Composiciones sublinguales de dexmedetomidina y métodos de uso de ellas
BR112012016853A2 (pt) "composições farmacêuticas para administração oral de peptídeos de insulina".
CL2011003160A1 (es) Compuestos derivados de heterociclicos, moduladores cb2; composicion farmaceutica que los comprende; y uso en el tratamiento de enfermedades reumaticas, autoinmune, inflamatorias, dolor, entre otras.
CL2008002984A1 (es) Composicion farmaceutica que comprende micofenolato sodico y su uso para el tratamiento y/o prevencion en enfermedades autoinmunes tales como el rechazo de aloinjertos o xenoinjertos de organos, celulas o tejidos y como antiinflamatorio.
CO6710913A2 (es) Uso de ácido lipasa lisosomal para tratar la deficiencia de ácido lipasa lisosomal en pacientes
CL2013000866A1 (es) Sales cristalinas oxalato y fosfato del conjugado naloxolpolietilenglicol; metodo de preparacion; composicion farmaceutica que lo comprende; y su uso para el tratamiento del dolor.
BR112013010829B8 (pt) Composição farmacêutica intravenosa para proporcionar alívio da dor e/ou da inflamação
MX349948B (es) Proteínas inmunógenas y composiciones para el tratamiento y prevención de streptococcus agalactiae.
CO7141430A2 (es) Formulaciones vesiculares para uso en el tratamiento del dolor o movilidad reducida de una articulación
BR112014020271A8 (pt) Composição farmacêutica e métodos para diminuir a frequência de micção em paciente
BR112017009510A2 (pt) composições compreendendo ciclosporina
CY1109537T1 (el) Πεπτιδια και παραγωγα πεπτιδιου, παρασκευη αυτων καθως επισης χρηση αυτων για την παρασκευη θεραπευτικως η/και προληπτικως δραστικης φαρμακευτικης συνθεσης
BR112015001627A2 (pt) composição farmacêutica, respectivos usos e método para diminuir a frequência de micção