EA201070790A1 - Реанимационная жидкость - Google Patents
Реанимационная жидкостьInfo
- Publication number
- EA201070790A1 EA201070790A1 EA201070790A EA201070790A EA201070790A1 EA 201070790 A1 EA201070790 A1 EA 201070790A1 EA 201070790 A EA201070790 A EA 201070790A EA 201070790 A EA201070790 A EA 201070790A EA 201070790 A1 EA201070790 A1 EA 201070790A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- resuscitation fluid
- reanimation
- liquid
- aqueous carrier
- lipid
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0026—Blood substitute; Oxygen transporting formulations; Plasma extender
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4172—Imidazole-alkanecarboxylic acids, e.g. histidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/38—Albumins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/38—Albumins
- A61K38/385—Serum albumin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- General Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Dermatology (AREA)
- Diabetes (AREA)
- Dispersion Chemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Описан способ лечения состояний, связанных в недостаточностью кровоснабжения, реанимационной жидкостью на основе липида. Эта реанимационная жидкость содержит липидный компонент и водный носитель. Этот липидный компонент образует эмульсию с водным носителем. Эта реанимационная жидкость может быть использована для увеличения кровяного давления и несения кислорода к тканям. Эта реанимационная жидкость может быть также использована для сохранения биологической целостности донорских органов для трансплантации.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US1644307P | 2007-12-22 | 2007-12-22 | |
US6463908P | 2008-03-18 | 2008-03-18 | |
PCT/US2008/013781 WO2009082449A2 (en) | 2007-12-22 | 2008-12-17 | Resuscitation fluid |
Publications (2)
Publication Number | Publication Date |
---|---|
EA201070790A1 true EA201070790A1 (ru) | 2011-02-28 |
EA022379B1 EA022379B1 (ru) | 2015-12-30 |
Family
ID=40789354
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA201070790A EA022379B1 (ru) | 2007-12-22 | 2008-12-17 | Способ лечения гиповолемии, ишемии и геморрагического шока у млекопитающих |
Country Status (15)
Country | Link |
---|---|
US (4) | US8063020B2 (ru) |
EP (2) | EP2227222B1 (ru) |
JP (1) | JP5690142B2 (ru) |
KR (1) | KR101623993B1 (ru) |
CN (1) | CN101917970B (ru) |
AP (1) | AP3197A (ru) |
AU (1) | AU2008341109B2 (ru) |
CA (1) | CA2710338C (ru) |
EA (1) | EA022379B1 (ru) |
ES (1) | ES2476258T3 (ru) |
HK (1) | HK1151972A1 (ru) |
IL (1) | IL206116A (ru) |
NZ (1) | NZ586233A (ru) |
WO (1) | WO2009082449A2 (ru) |
ZA (1) | ZA201005150B (ru) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8618056B2 (en) | 2007-12-22 | 2013-12-31 | Cuthbert O. Simpkins | Methods and compositions for treating conditions related to lack of blood supply, shock and neuronal injuries |
US8063020B2 (en) | 2007-12-22 | 2011-11-22 | Simpkins Cuthbert O | Resuscitation fluid |
US8906855B2 (en) | 2007-12-22 | 2014-12-09 | Vivacelle Bio, Inc. | Methods and compositions for treating conditions related to lack of blood supply, shock and neuronal injuries |
WO2010087986A2 (en) * | 2009-01-30 | 2010-08-05 | Simpkins Cuthbert O | Resuscitation fluid |
WO2012096697A1 (en) * | 2011-01-14 | 2012-07-19 | Simpkins Cuthbert O | Methods and compositions for treating conditions related to lack of blood supply, shock and neuronal injuries |
US10357450B2 (en) | 2012-04-06 | 2019-07-23 | Children's Medical Center Corporation | Process for forming microbubbles with high oxygen content and uses thereof |
BR112015002807A2 (pt) * | 2012-08-10 | 2018-03-20 | Vivacelle Bio, Inc. | expansor de volume sanguíneo, métodos para tratar condições relacionadas com a falta de suprimento de sangue e para aumentar a pressão sanguínea em paciente com hipovolemia e respectivos usos |
US10577554B2 (en) | 2013-03-15 | 2020-03-03 | Children's Medical Center Corporation | Gas-filled stabilized particles and methods of use |
EP3307283B1 (en) * | 2015-06-10 | 2020-09-02 | Cellphire Inc. | Composition and methods for treatment of loss of fluids leading to hypotension and/or hypovolemia |
RU2618200C1 (ru) * | 2016-01-11 | 2017-05-02 | государственное бюджетное образовательное учреждение высшего профессионального образования "Омский государственный медицинский университет" Министерства здравоохранения Российской Федерации (ГБОУ ВПО ОмГМУ Минздрава России) | Способ патогенетически обоснованной оценки гиповолемии у больных с травматическим шоком II и III степени тяжести |
US9649335B1 (en) * | 2016-03-30 | 2017-05-16 | Baylor University | Intravenous administration of an oxygen-enabled fluid |
US9801906B2 (en) * | 2016-03-30 | 2017-10-31 | Baylor University | Oxygen-enabled fluid |
WO2017222912A1 (en) * | 2016-06-20 | 2017-12-28 | Vivacelle Bio, Inc. | Compositions and methods for reducing reperfusion injury |
CN106237314A (zh) * | 2016-08-30 | 2016-12-21 | 中国科学院长春应用化学研究所 | 一种应用于宠物失血休克急救的复苏液及其制备方法 |
WO2018039754A1 (pt) * | 2016-09-01 | 2018-03-08 | Bebeachibuli Romeo | Formulação à base de fatores alimentares, produtos obtidos com o uso da formulação e processos de obtenção |
US11147890B2 (en) | 2017-02-28 | 2021-10-19 | Children's Medical Center Corporation | Stimuli-responsive particles encapsulating a gas and methods of use |
US12005130B2 (en) | 2019-10-16 | 2024-06-11 | Agitated Solutions Inc. | Generating microbubbles for bubble studies |
US11191888B1 (en) | 2020-05-18 | 2021-12-07 | Agitated Solutions Inc. | Syringe-based microbubble generator |
CN116076484A (zh) * | 2022-11-30 | 2023-05-09 | 武汉大学 | 一种修复肾脏损伤的低温携氧机械灌注液及其应用 |
Family Cites Families (28)
Publication number | Priority date | Publication date | Assignee | Title |
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JPS5835485B2 (ja) * | 1976-02-03 | 1983-08-03 | 株式会社ミドリ十字 | 酸素運搬輸液 |
US4182750A (en) | 1977-04-21 | 1980-01-08 | Sullivan Thomas E | Bloodcompatible functional polymers |
JPS5727624A (en) * | 1980-07-28 | 1982-02-15 | Japax Inc | Automatic wire setting device of wire type electric discharge processing machine |
US4425334A (en) | 1982-04-02 | 1984-01-10 | The Regents Of The University Of California | Functional oxygen transport system |
US4911929A (en) | 1986-08-29 | 1990-03-27 | The United States Of America As Represented By The Secretary Of The Navy | Blood substitute comprising liposome-encapsulated hemoglobin |
US5061688A (en) * | 1988-08-19 | 1991-10-29 | Illinois Institute Of Technology | Hemoglobin multiple emulsion |
WO1992022202A1 (en) * | 1991-06-03 | 1992-12-23 | Alpha Therapeutics Corporation | Thrombolytic and perfluorochemical treatment for myocardial infraction |
US5284663A (en) | 1991-07-23 | 1994-02-08 | Temple University | Salt film encapsulated perfluorocarbons |
JPH05320043A (ja) * | 1992-05-20 | 1993-12-03 | Terumo Corp | リポポリサッカライド捕捉剤 |
EP0693924B2 (en) * | 1993-02-22 | 2008-04-09 | Abraxis BioScience, Inc. | Methods for (in vivo) delivery of biologics and compositions useful therefor |
US5576016A (en) | 1993-05-18 | 1996-11-19 | Pharmos Corporation | Solid fat nanoemulsions as drug delivery vehicles |
US5834519A (en) | 1996-10-11 | 1998-11-10 | Wayne State University | Stabilized gas-supersaturated emulsions and suspensions |
US6261537B1 (en) | 1996-10-28 | 2001-07-17 | Nycomed Imaging As | Diagnostic/therapeutic agents having microbubbles coupled to one or more vectors |
US6537246B1 (en) | 1997-06-18 | 2003-03-25 | Imarx Therapeutics, Inc. | Oxygen delivery agents and uses for the same |
SE0000730D0 (sv) | 2000-03-06 | 2000-03-06 | Scotia Holdings Plc | Lipid carrier |
DK1349545T3 (da) * | 2000-12-05 | 2009-02-16 | Los Angeles Childrens Hospital | Farmaceutiske præparater af fenretinid med öget biotilgængelighed samt fremgangsmåder til anvendelse deraf |
US20020172710A1 (en) | 2001-05-16 | 2002-11-21 | Twine Rebecca Wright | Clinical use of liposome technology for the delivery of nutrients to patients with the short bowel syndrome |
EP1279400A1 (en) | 2001-07-25 | 2003-01-29 | Target Hit sa | Modifying the fatty acid composition of cell membranes of organs and tissues |
US20050260189A1 (en) | 2002-07-11 | 2005-11-24 | Klibanov Alexander L | Microbubble compositions, and methods for preparing and using same |
US20060166182A1 (en) | 2002-12-31 | 2006-07-27 | The Board Of Trustees Of The University Of Ilinois A Body Corporate And Politic Of The State Of Il. | Tissue and organ preservation, protection and resuscitation |
JP2004307404A (ja) * | 2003-04-08 | 2004-11-04 | Nipro Corp | 人工酸素運搬体を含む医薬組成物 |
RU2259819C1 (ru) * | 2004-03-01 | 2005-09-10 | Кузнецова Ирина Николаевна | Эмульсия перфторорганических соединений медицинского назначения и способ её получения |
US7871632B2 (en) * | 2004-07-12 | 2011-01-18 | Adventrx Pharmaceuticals, Inc. | Compositions for delivering highly water soluble drugs |
CN1669578A (zh) * | 2004-10-15 | 2005-09-21 | 梁玉英 | 一种治疗心脑血管疾病的针剂及其制备方法 |
US20060088583A1 (en) | 2004-10-25 | 2006-04-27 | Oxygenix Co., Ltd. | Artificial oxygen carrier containing preventive agents of metHb formation |
WO2009043031A2 (en) | 2007-09-27 | 2009-04-02 | Children's Medical Center Corporation | Microbubbles and methods for oxygen delivery |
US8063020B2 (en) | 2007-12-22 | 2011-11-22 | Simpkins Cuthbert O | Resuscitation fluid |
WO2010087986A2 (en) | 2009-01-30 | 2010-08-05 | Simpkins Cuthbert O | Resuscitation fluid |
-
2008
- 2008-12-16 US US12/314,737 patent/US8063020B2/en active Active
- 2008-12-17 AP AP2010005297A patent/AP3197A/xx active
- 2008-12-17 EP EP08865306.8A patent/EP2227222B1/en active Active
- 2008-12-17 JP JP2010539463A patent/JP5690142B2/ja active Active
- 2008-12-17 WO PCT/US2008/013781 patent/WO2009082449A2/en active Application Filing
- 2008-12-17 CN CN2008801223673A patent/CN101917970B/zh active Active
- 2008-12-17 NZ NZ586233A patent/NZ586233A/en unknown
- 2008-12-17 EP EP14158191.8A patent/EP2749268B1/en active Active
- 2008-12-17 AU AU2008341109A patent/AU2008341109B2/en active Active
- 2008-12-17 KR KR1020107016314A patent/KR101623993B1/ko active IP Right Grant
- 2008-12-17 EA EA201070790A patent/EA022379B1/ru not_active IP Right Cessation
- 2008-12-17 CA CA2710338A patent/CA2710338C/en active Active
- 2008-12-17 ES ES08865306.8T patent/ES2476258T3/es active Active
-
2010
- 2010-05-31 IL IL206116A patent/IL206116A/en active IP Right Grant
- 2010-07-20 ZA ZA2010/05150A patent/ZA201005150B/en unknown
-
2011
- 2011-06-14 HK HK11106067.2A patent/HK1151972A1/xx unknown
- 2011-10-12 US US13/271,872 patent/US8198243B2/en active Active
- 2011-10-12 US US13/271,795 patent/US8367613B2/en active Active
-
2012
- 2012-12-07 US US13/708,411 patent/US8569236B2/en active Active
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
Designated state(s): AM AZ BY KZ KG MD TJ TM |