EA200802333A1 - Соль органической кислоты, способ получения соли органической кислоты, способы и средства для лечения новообразований и лечения злокачественных новообразований крови, набор, стерильный водный раствор и композиции в упакованном и неупакованном видах - Google Patents

Соль органической кислоты, способ получения соли органической кислоты, способы и средства для лечения новообразований и лечения злокачественных новообразований крови, набор, стерильный водный раствор и композиции в упакованном и неупакованном видах

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Publication number
EA200802333A1
EA200802333A1 EA200802333A EA200802333A EA200802333A1 EA 200802333 A1 EA200802333 A1 EA 200802333A1 EA 200802333 A EA200802333 A EA 200802333A EA 200802333 A EA200802333 A EA 200802333A EA 200802333 A1 EA200802333 A1 EA 200802333A1
Authority
EA
Eurasian Patent Office
Prior art keywords
organic acid
treatment
salt
formation
kompypsy
Prior art date
Application number
EA200802333A
Other languages
English (en)
Other versions
EA016995B1 (ru
Inventor
Ли С. Чонг
Уильям Э. Ли
Эйдриен С. Рэй
Ханс К. Рейзер
Дэниел Б. Тамэс
Уильям Дж. Уоткинс
Original Assignee
Джилид Сайэнс, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Джилид Сайэнс, Инк. filed Critical Джилид Сайэнс, Инк.
Publication of EA200802333A1 publication Critical patent/EA200802333A1/ru
Publication of EA016995B1 publication Critical patent/EA016995B1/ru

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C07F9/65616—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Processing Of Solid Wastes (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Соединение формулы (1) и/или его соли, таутомеры или сольваты применяют для лечения злокачественых заболеваний крови. В соответствии с вариантом осуществления изобретения предложена соль органической кислоты соединения 1 для общего использования при лечении опухолей. В соответствии с еще одним вариантом осуществления изобретения соль стабилизируют с помощью углевода.
EA200802333A 2006-05-16 2007-05-16 Соль карбоновой кислоты фосфонамидного производного 2,6-диаминопурина, способы и средства для лечения новообразований и лечения злокачественных новообразований крови, набор, стерильный водный раствор и композиция EA016995B1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US80098306P 2006-05-16 2006-05-16
US83180506P 2006-07-18 2006-07-18
PCT/US2007/011726 WO2007136650A2 (en) 2006-05-16 2007-05-16 Method and compositions for treating hematological malignancies

Publications (2)

Publication Number Publication Date
EA200802333A1 true EA200802333A1 (ru) 2009-04-28
EA016995B1 EA016995B1 (ru) 2012-09-28

Family

ID=38578698

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200802333A EA016995B1 (ru) 2006-05-16 2007-05-16 Соль карбоновой кислоты фосфонамидного производного 2,6-диаминопурина, способы и средства для лечения новообразований и лечения злокачественных новообразований крови, набор, стерильный водный раствор и композиция

Country Status (20)

Country Link
US (3) US20090258840A1 (ru)
EP (1) EP2020996B1 (ru)
JP (2) JP5544165B2 (ru)
KR (1) KR101424832B1 (ru)
CN (1) CN101442994B (ru)
AT (1) ATE534377T1 (ru)
AU (1) AU2007254309B2 (ru)
BR (1) BRPI0711646C1 (ru)
CA (1) CA2652048C (ru)
CY (1) CY1112377T1 (ru)
DK (1) DK2020996T3 (ru)
EA (1) EA016995B1 (ru)
ES (1) ES2377467T3 (ru)
HK (1) HK1127913A1 (ru)
MX (1) MX2008014665A (ru)
NZ (1) NZ572368A (ru)
PL (1) PL2020996T3 (ru)
PT (1) PT2020996E (ru)
SI (1) SI2020996T1 (ru)
WO (1) WO2007136650A2 (ru)

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Also Published As

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BRPI0711646A2 (pt) 2011-11-29
US20090258840A1 (en) 2009-10-15
DK2020996T3 (da) 2012-02-27
US20080039427A1 (en) 2008-02-14
NZ572368A (en) 2011-04-29
CN101442994B (zh) 2013-03-06
BRPI0711646C1 (pt) 2021-05-25
WO2007136650A2 (en) 2007-11-29
CA2652048A1 (en) 2007-11-29
EP2020996B1 (en) 2011-11-23
HK1127913A1 (en) 2009-10-09
CA2652048C (en) 2012-12-11
ES2377467T3 (es) 2012-03-27
PT2020996E (pt) 2012-02-20
BRPI0711646B1 (pt) 2020-12-01
AU2007254309B2 (en) 2012-05-03
ATE534377T1 (de) 2011-12-15
PL2020996T3 (pl) 2012-04-30
SI2020996T1 (sl) 2012-03-30
BRPI0711646B8 (pt) 2021-04-06
KR20090015122A (ko) 2009-02-11
JP2013100324A (ja) 2013-05-23
JP2009537539A (ja) 2009-10-29
EP2020996A2 (en) 2009-02-11
US8435969B2 (en) 2013-05-07
AU2007254309A1 (en) 2007-11-29
US20110172192A1 (en) 2011-07-14
MX2008014665A (es) 2008-11-28
WO2007136650A3 (en) 2008-01-24
CN101442994A (zh) 2009-05-27
JP5544165B2 (ja) 2014-07-09
EA016995B1 (ru) 2012-09-28
CY1112377T1 (el) 2015-12-09
KR101424832B1 (ko) 2014-08-06

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