EA200970192A1 - Производные 5,6-бисарил-2-пиридин-карбоксамида, их получение и их применение в терапии в качестве антагонистов рецепторов уротензина ii - Google Patents

Производные 5,6-бисарил-2-пиридин-карбоксамида, их получение и их применение в терапии в качестве антагонистов рецепторов уротензина ii

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Publication number
EA200970192A1
EA200970192A1 EA200970192A EA200970192A EA200970192A1 EA 200970192 A1 EA200970192 A1 EA 200970192A1 EA 200970192 A EA200970192 A EA 200970192A EA 200970192 A EA200970192 A EA 200970192A EA 200970192 A1 EA200970192 A1 EA 200970192A1
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Eurasian Patent Office
Prior art keywords
therapy
urotenzin
bisaril
carboxamide
pyridin
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EA200970192A
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English (en)
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EA016352B1 (ru
Inventor
Жан-Мишель Альтенбюрже
Валери Фоссе
Жильбер Лассалль
Фредерик Пети
Жан-Клод Верньер
Филип Жаниак
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Санофи-Авентис
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Publication of EA200970192A1 publication Critical patent/EA200970192A1/ru
Publication of EA016352B1 publication Critical patent/EA016352B1/ru

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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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Abstract

Изобретение касается соединений, отвечающих формуле (I)в которой X, Y, U, А, В, W, Z, R1 и R2 являются такими, как определено в описании. Способ получения и применение в терапии.
EA200970192A 2006-08-11 2007-08-09 Производные 5,6-бис-арил-2-пиридинкарбоксамида, их получение и их применение в терапии в качестве антагонистов рецепторов уротензина ii EA016352B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0607283A FR2904827B1 (fr) 2006-08-11 2006-08-11 Derives de 5,6-bisaryl-2-pyridine-carboxamide, leur preparation et leur application en therapeutique comme antiganistes des recepteurs a l'urotensine ii
PCT/FR2007/001357 WO2008020124A1 (fr) 2006-08-11 2007-08-09 Dérivés de 5,6-bisaryl-2-pyridine-carboxamide, leur préparation et leur application en thérapeutique comme antagonistes des recepteurs a l'urotensine ii

Publications (2)

Publication Number Publication Date
EA200970192A1 true EA200970192A1 (ru) 2009-08-28
EA016352B1 EA016352B1 (ru) 2012-04-30

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EA200970192A EA016352B1 (ru) 2006-08-11 2007-08-09 Производные 5,6-бис-арил-2-пиридинкарбоксамида, их получение и их применение в терапии в качестве антагонистов рецепторов уротензина ii

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US (2) US8110579B2 (ru)
EP (2) EP2439193B1 (ru)
JP (1) JP5230621B2 (ru)
KR (1) KR20090050075A (ru)
CN (1) CN101511789B (ru)
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AU (1) AU2007285659B2 (ru)
BR (1) BRPI0716655A2 (ru)
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DK (1) DK2059508T3 (ru)
EA (1) EA016352B1 (ru)
ES (1) ES2385614T3 (ru)
FR (1) FR2904827B1 (ru)
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HK (1) HK1135903A1 (ru)
HR (1) HRP20120559T1 (ru)
IL (1) IL196797A (ru)
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MY (1) MY145644A (ru)
NO (1) NO20090779L (ru)
NZ (1) NZ574699A (ru)
PE (1) PE20080421A1 (ru)
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FR2948119A1 (fr) 2009-07-16 2011-01-21 Sanofi Aventis Derives de 5,6-bisaryl-2-pyridine-carboxamide, leur preparation et leur application en therapeutique comme antagonistes des recepteurs a l'urotensine ii
FR2948120A1 (fr) * 2009-07-16 2011-01-21 Sanofi Aventis Derives de 5,6-bisaryl-2-pyrimidine-carboxamide, leur preparation et leur application en therapeutique comme antagonistes des recepteurs a l’urotensine ii
AR079022A1 (es) * 2009-11-02 2011-12-21 Sanofi Aventis Derivados de acido carboxilico ciclico sustituidos con acilamino, su uso como productos farmaceuticos, composicion farmaceutica y metodo de preparacion
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TW201444798A (zh) 2013-02-28 2014-12-01 必治妥美雅史谷比公司 作爲強效ｒｏｃｋ１及ｒｏｃｋ２抑制劑之苯基吡唑衍生物
KR20160003647A (ko) 2013-03-15 2016-01-11 에피자임, 인코포레이티드 Carm1 억제제 및 이의 용도
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ZA200900835B (en) 2010-06-30
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IL196797A (en) 2013-07-31
HK1135903A1 (ru) 2010-06-18
AR062294A1 (es) 2008-10-29
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PL2059508T3 (pl) 2012-09-28
CA2659928A1 (fr) 2008-02-21
EP2439193A1 (fr) 2012-04-11
WO2008020124A1 (fr) 2008-02-21
EA016352B1 (ru) 2012-04-30
EP2059508B1 (fr) 2012-04-11
MY145644A (en) 2012-03-15
CN101511789A (zh) 2009-08-19
PE20080421A1 (es) 2008-06-17
US8110579B2 (en) 2012-02-07
JP5230621B2 (ja) 2013-07-10
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US8552201B2 (en) 2013-10-08
AU2007285659A1 (en) 2008-02-21
US20120108611A1 (en) 2012-05-03
CR10603A (es) 2009-07-03
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CL2007002329A1 (es) 2008-03-07
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AU2007285659B2 (en) 2013-01-10
IL196797A0 (en) 2009-11-18
FR2904827B1 (fr) 2008-09-19
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