EA200900249A1 - Фармацевтическая композиция и способ ее получения - Google Patents
Фармацевтическая композиция и способ ее полученияInfo
- Publication number
- EA200900249A1 EA200900249A1 EA200900249A EA200900249A EA200900249A1 EA 200900249 A1 EA200900249 A1 EA 200900249A1 EA 200900249 A EA200900249 A EA 200900249A EA 200900249 A EA200900249 A EA 200900249A EA 200900249 A1 EA200900249 A1 EA 200900249A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- cellulose
- preparation
- pharmaceutical composition
- disintegrant
- methyl cellulose
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Addiction (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Emergency Medicine (AREA)
- Psychiatry (AREA)
- Rheumatology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Твердая фармацевтическая композиция в форме желатиновых капсул, содержащая, по меньшей мере, одно действующее начало, а также по меньшей мере один гелеобразователь, выбранный из числа производных целлюлозы, таких как гидроксиэтилцеллюлоза, гидроксипропилцеллюлоза, гидроксипропилметилцеллюлоза, метилцеллюлоза, этилметилцеллюлоза, натриевая соль карбоксиметилцеллюлозы (CMC) и кальциевая соль карбоксиметилцеллюлозы, и по меньшей мере один разрыхлитель, при этом гелеобразователь и разрыхлитель присутствуют в массовом соотношении от 0,3 до 0,7/1, и массовая доля гелеобразователя(ей) составляет от 10 до 20% композиции, и способ ее приготовления.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0606956A FR2904225B1 (fr) | 2006-07-28 | 2006-07-28 | Compositions pharmaceutiques de substances actives difficilement detournables de la voie d'administration a laquelle elles sont destinees |
| PCT/FR2007/051724 WO2008012474A2 (fr) | 2006-07-28 | 2007-07-25 | Compositions pharmaceutiques de substances actives difficilement detournables de la voie d'administration a laquelle elles sont destinees |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EA200900249A1 true EA200900249A1 (ru) | 2009-06-30 |
| EA021902B1 EA021902B1 (ru) | 2015-09-30 |
Family
ID=37776622
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA200900249A EA021902B1 (ru) | 2006-07-28 | 2007-07-25 | Твердая фармацевтическая композиция, образующая гель в присутствии воды, и твердая капсула, содержащая ее |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20100015219A1 (ru) |
| EP (1) | EP2046301B1 (ru) |
| CY (1) | CY1118290T1 (ru) |
| DK (1) | DK2046301T3 (ru) |
| EA (1) | EA021902B1 (ru) |
| ES (1) | ES2605018T3 (ru) |
| FR (1) | FR2904225B1 (ru) |
| HU (1) | HUE031339T2 (ru) |
| LT (1) | LT2046301T (ru) |
| PL (1) | PL2046301T3 (ru) |
| PT (1) | PT2046301T (ru) |
| SI (1) | SI2046301T1 (ru) |
| UA (1) | UA94275C2 (ru) |
| WO (1) | WO2008012474A2 (ru) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8829020B2 (en) | 2009-07-16 | 2014-09-09 | Mallinckrodt Llc | Compounds and compositions for use in phototherapy and in treatment of ocular neovascular disease and cancers |
| JP6199321B2 (ja) * | 2012-03-02 | 2017-09-20 | ローズ ファーマシューティカルズ エル．ピー． | 不正使用抵抗性の即時放出製剤 |
| IT201600122469A1 (it) | 2016-12-02 | 2018-06-02 | E Pharma Trento S P A | Composizione farmaceutica solida a prova di abuso |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2530563C2 (de) * | 1975-07-09 | 1986-07-24 | Bayer Ag, 5090 Leverkusen | Analgetische Arzneimittel mit vermindertem Mißbrauchspotential |
| FR2787715B1 (fr) * | 1998-12-23 | 2002-05-10 | Synthelabo | Composition pharmaceutique comprenant un compose hypnotique ou un de ses sels pharmaceutiquement acceptables |
| US20020035188A1 (en) * | 2000-07-21 | 2002-03-21 | Steeghs Henricus Renier Gerardus | Agglomerating particulate materials |
| US20040126428A1 (en) * | 2001-11-02 | 2004-07-01 | Lyn Hughes | Pharmaceutical formulation including a resinate and an aversive agent |
| DE10209979A1 (de) * | 2002-03-07 | 2003-09-25 | Ratiopharm Gmbh | Arzneimittel mit Cholesterolspiegel-senkenden Wirkstoffen mit zeitverzögerter Wirkstofffreisetzung |
| US20050165038A1 (en) * | 2004-01-22 | 2005-07-28 | Maxwell Gordon | Analgetic dosage forms that are resistant to parenteral and inhalation dosing and have reduced side effects |
| US20060110327A1 (en) * | 2004-11-24 | 2006-05-25 | Acura Pharmaceuticals, Inc. | Methods and compositions for deterring abuse of orally administered pharmaceutical products |
-
2006
- 2006-07-28 FR FR0606956A patent/FR2904225B1/fr active Active
-
2007
- 2007-07-25 US US12/375,452 patent/US20100015219A1/en not_active Abandoned
- 2007-07-25 SI SI200731869A patent/SI2046301T1/sl unknown
- 2007-07-25 LT LTEP07823641.1T patent/LT2046301T/lt unknown
- 2007-07-25 EA EA200900249A patent/EA021902B1/ru unknown
- 2007-07-25 HU HUE07823641A patent/HUE031339T2/en unknown
- 2007-07-25 UA UAA200901756A patent/UA94275C2/ru unknown
- 2007-07-25 PT PT78236411T patent/PT2046301T/pt unknown
- 2007-07-25 DK DK07823641.1T patent/DK2046301T3/da active
- 2007-07-25 PL PL07823641T patent/PL2046301T3/pl unknown
- 2007-07-25 WO PCT/FR2007/051724 patent/WO2008012474A2/fr active Application Filing
- 2007-07-25 ES ES07823641.1T patent/ES2605018T3/es active Active
- 2007-07-25 EP EP07823641.1A patent/EP2046301B1/fr active Active
-
2016
- 2016-12-05 CY CY20161101250T patent/CY1118290T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SI2046301T1 (sl) | 2017-02-28 |
| CY1118290T1 (el) | 2017-06-28 |
| EP2046301B1 (fr) | 2016-09-14 |
| HUE031339T2 (en) | 2017-06-28 |
| WO2008012474A3 (fr) | 2008-03-27 |
| PT2046301T (pt) | 2016-12-13 |
| EA021902B1 (ru) | 2015-09-30 |
| UA94275C2 (ru) | 2011-04-26 |
| ES2605018T3 (es) | 2017-03-10 |
| FR2904225B1 (fr) | 2010-08-13 |
| DK2046301T3 (da) | 2017-01-02 |
| US20100015219A1 (en) | 2010-01-21 |
| EP2046301A2 (fr) | 2009-04-15 |
| PL2046301T3 (pl) | 2017-03-31 |
| LT2046301T (lt) | 2017-01-25 |
| FR2904225A1 (fr) | 2008-02-01 |
| WO2008012474A2 (fr) | 2008-01-31 |
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