EA200802358A1 - Композиция для инактивации оболочечного вируса (варианты), способ лечения вирусного заболевания с ее помощью, средства на ее основе для изготовления лекарства против вирусного заболевания, для изготовления больших количеств биосовместимого дезинфецирующего средства и для изготовления покрытия, содержащий ее набор для инактивации оболочечного вируса и способ инактивации оболочечного вируса - Google Patents

Композиция для инактивации оболочечного вируса (варианты), способ лечения вирусного заболевания с ее помощью, средства на ее основе для изготовления лекарства против вирусного заболевания, для изготовления больших количеств биосовместимого дезинфецирующего средства и для изготовления покрытия, содержащий ее набор для инактивации оболочечного вируса и способ инактивации оболочечного вируса

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Publication number
EA200802358A1
EA200802358A1 EA200802358A EA200802358A EA200802358A1 EA 200802358 A1 EA200802358 A1 EA 200802358A1 EA 200802358 A EA200802358 A EA 200802358A EA 200802358 A EA200802358 A EA 200802358A EA 200802358 A1 EA200802358 A1 EA 200802358A1
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EA
Eurasian Patent Office
Prior art keywords
inactivation
virus
viral diseases
manufacturing
enveloped
Prior art date
Application number
EA200802358A
Other languages
English (en)
Other versions
EA016073B1 (ru
Inventor
Тьери Пеле
Доналд Ф.Х. Уалах
Original Assignee
Вайэроблок С.А.
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Publication date
Application filed by Вайэроблок С.А. filed Critical Вайэроблок С.А.
Publication of EA200802358A1 publication Critical patent/EA200802358A1/ru
Publication of EA016073B1 publication Critical patent/EA016073B1/ru

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • A61K9/1271Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716Glucans
    • A61K31/724Cyclodextrins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02Local antiseptics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/18011Paramyxoviridae
    • C12N2760/18811Sendai virus
    • C12N2760/18861Methods of inactivation or attenuation
    • C12N2760/18863Methods of inactivation or attenuation by chemical treatment
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

Настоящее изобретение преимущественно относится к области предотвращения заболеваний, вызываемых оболочечными вирусами. Более конкретно, данное изобретение касается композиции для инактивации оболочечного вируса, содержащей по меньшей мере одну нефосфолипидную липосому (НФЛ), способную взаимодействовать с упомянутым оболочечным вирусом и с агентом, который усиливает липидный обмен между упомянутой НФЛ и мембраной упомянутого оболочечного вируса.
EA200802358A 2006-05-19 2007-05-18 Композиция для инактивации оболочечного вируса (варианты), средства на ее основе для приготовления лекарства против вирусного заболевания, для приготовления больших количеств биосовместимого дезинфицирующего средства и для приготовления покрытия, содержащий ее набор для инактивации оболочечного вируса и способ инактивации оболочечного вируса EA016073B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US80140006P 2006-05-19 2006-05-19
PCT/IB2007/001286 WO2007135523A2 (en) 2006-05-19 2007-05-18 A composition for inactivating an enveloped virus

Publications (2)

Publication Number Publication Date
EA200802358A1 true EA200802358A1 (ru) 2009-04-28
EA016073B1 EA016073B1 (ru) 2012-01-30

Family

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EA200802358A EA016073B1 (ru) 2006-05-19 2007-05-18 Композиция для инактивации оболочечного вируса (варианты), средства на ее основе для приготовления лекарства против вирусного заболевания, для приготовления больших количеств биосовместимого дезинфицирующего средства и для приготовления покрытия, содержащий ее набор для инактивации оболочечного вируса и способ инактивации оболочечного вируса

Country Status (14)

Country Link
US (2) US8889398B2 (ru)
EP (1) EP2023896B8 (ru)
JP (1) JP5259578B2 (ru)
KR (1) KR101352165B1 (ru)
CN (1) CN101448486B (ru)
AU (1) AU2007252967B2 (ru)
BR (1) BRPI0712074A2 (ru)
CA (1) CA2652362C (ru)
DK (1) DK2023896T3 (ru)
EA (1) EA016073B1 (ru)
ES (1) ES2590812T3 (ru)
HK (1) HK1131554A1 (ru)
IL (1) IL195317A (ru)
WO (1) WO2007135523A2 (ru)

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CN102068425A (zh) * 2011-02-12 2011-05-25 李春娟 改良的磷酸奥司他韦药物组合物
PT3471732T (pt) * 2016-06-16 2020-08-24 Combioxin Sa Lipossomas para o tratamento de infeções virais
MX2020004151A (es) * 2017-10-30 2020-08-13 Takeda Pharmaceuticals Co Detergentes compatibles con el medio ambiente para la inactivacion de virus envueltos en lipidos.
WO2021191141A1 (en) * 2020-03-26 2021-09-30 Heiq Materials Ag Antiviral surface coating for metal and plastic surfaces
US20230227506A1 (en) 2020-06-18 2023-07-20 The University Of Bristol Fatty Acid Complexes Of Coronavirus Spike Protein And Their Use

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Also Published As

Publication number Publication date
JP5259578B2 (ja) 2013-08-07
WO2007135523A3 (en) 2008-06-26
IL195317A0 (en) 2009-08-03
CN101448486B (zh) 2012-10-31
US9526700B2 (en) 2016-12-27
JP2009537508A (ja) 2009-10-29
IL195317A (en) 2014-02-27
US20150065458A1 (en) 2015-03-05
WO2007135523A2 (en) 2007-11-29
EP2023896B1 (en) 2016-07-13
EA016073B1 (ru) 2012-01-30
HK1131554A1 (en) 2010-01-29
EP2023896A2 (en) 2009-02-18
DK2023896T3 (en) 2016-10-03
AU2007252967B2 (en) 2011-11-10
KR101352165B1 (ko) 2014-01-15
KR20090014178A (ko) 2009-02-06
CA2652362A1 (en) 2007-11-29
US8889398B2 (en) 2014-11-18
EP2023896B8 (en) 2016-09-14
CN101448486A (zh) 2009-06-03
AU2007252967A1 (en) 2007-11-29
CA2652362C (en) 2014-10-07
BRPI0712074A2 (pt) 2012-01-17
US20100137437A1 (en) 2010-06-03
ES2590812T3 (es) 2016-11-23

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