EA200801411A1 - Новые адъюванты на основе конъюгатов и производных бис-ацилоксипропилцистеина и их применения в фармацевтических композициях - Google Patents
Новые адъюванты на основе конъюгатов и производных бис-ацилоксипропилцистеина и их применения в фармацевтических композицияхInfo
- Publication number
- EA200801411A1 EA200801411A1 EA200801411A EA200801411A EA200801411A1 EA 200801411 A1 EA200801411 A1 EA 200801411A1 EA 200801411 A EA200801411 A EA 200801411A EA 200801411 A EA200801411 A EA 200801411A EA 200801411 A1 EA200801411 A1 EA 200801411A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- pharmaceutical compositions
- bis
- acyloxypropylcystein
- conjugates
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C321/00—Thiols, sulfides, hydropolysulfides or polysulfides
- C07C321/12—Sulfides, hydropolysulfides, or polysulfides having thio groups bound to acyclic carbon atoms
- C07C321/14—Sulfides, hydropolysulfides, or polysulfides having thio groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/10—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C323/11—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C323/24—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/25—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Transplantation (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Pulmonology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05025431A EP1787660A1 (en) | 2005-11-22 | 2005-11-22 | New adjuvants on the basis of bisacyloxypropylcysteine conjugates and their uses in pharmaceutical compositions |
| PCT/EP2006/011182 WO2007059931A1 (en) | 2005-11-22 | 2006-11-22 | New adjuvants on the basis of bisacyloxypropylcysteine conjugates and derivatives and their uses in pharmaceutical compositions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EA200801411A1 true EA200801411A1 (ru) | 2008-10-30 |
Family
ID=35787974
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA200801411A EA200801411A1 (ru) | 2005-11-22 | 2006-11-22 | Новые адъюванты на основе конъюгатов и производных бис-ацилоксипропилцистеина и их применения в фармацевтических композициях |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US8119689B2 (ja) |
| EP (2) | EP1787660A1 (ja) |
| JP (1) | JP5249041B2 (ja) |
| KR (1) | KR20080069267A (ja) |
| CN (1) | CN101360514A (ja) |
| AU (1) | AU2006316791B2 (ja) |
| BR (1) | BRPI0618847A2 (ja) |
| CA (1) | CA2628736A1 (ja) |
| EA (1) | EA200801411A1 (ja) |
| WO (1) | WO2007059931A1 (ja) |
| ZA (1) | ZA200804163B (ja) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2196196A1 (en) * | 2008-12-10 | 2010-06-16 | Medipol S.A. | Compound, medicament, vaccine composition and nanocapsules |
| EP2305283A1 (en) * | 2009-09-24 | 2011-04-06 | Helmholtz-Zentrum für Infektionsforschung GmbH | Pharmaceutical compositions for treating dysregulated inflammatory diseases |
| WO2011138050A1 (en) | 2010-05-07 | 2011-11-10 | Helmholtz-Zentrum für Infektionsforschung GmbH | Method for vaccination |
| US9061066B2 (en) * | 2010-06-04 | 2015-06-23 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Immunoadjuvant compounds and uses thereof |
| US20130259928A1 (en) * | 2010-09-30 | 2013-10-03 | Franvax S.R.L. | Generation of virosome particles |
| CN105764502A (zh) | 2013-07-26 | 2016-07-13 | 现代化制药公司 | 改善比生群及其类似物及衍生物的治疗益处的组合方法 |
| CN105126092A (zh) * | 2015-09-30 | 2015-12-09 | 青岛农业大学 | 一种以壳寡糖为佐剂负载大肠杆菌菌毛黏附素的鸭疫里默氏菌菌影疫苗的制备方法及其应用 |
| JP2021515797A (ja) * | 2018-03-15 | 2021-06-24 | アトッサ・セラピューティクス・インコーポレイテッド | 免疫反応誘導のインサイツ方法 |
| BR112021025630A8 (pt) * | 2019-06-26 | 2023-04-11 | Axelia Oncology Pty Ltd | Moléculas novas |
| CN112826928A (zh) * | 2020-11-20 | 2021-05-25 | 郑州大学 | 一种cd40靶向树突状细胞纳米疫苗及其构建方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2480196C (en) | 2002-04-04 | 2015-05-12 | Gbf Gesellschaft Fuer Biotechnologische Forschung Mbh | Use of a lipopeptide or lipoprotein as an adjuvant in therapeutic or prophylactic vaccinations |
| EP1382352A1 (de) | 2002-07-19 | 2004-01-21 | GBF Gesellschaft für Biotechnologische Forschung mbH | Bisacyloxypropylcystein-Konjugate und deren Verwendung |
| JP4412461B2 (ja) * | 2002-11-20 | 2010-02-10 | 日油株式会社 | 修飾された生体関連物質、その製造方法および中間体 |
| WO2004084938A1 (en) * | 2003-03-24 | 2004-10-07 | Intercell Ag | Improved vaccines |
| DE10326303A1 (de) * | 2003-06-11 | 2004-12-30 | Celares Gmbh | Reagenzien zur Modifikation von Biopharmazeutika, deren Herstellung und Anwendung |
-
2005
- 2005-11-22 EP EP05025431A patent/EP1787660A1/en not_active Withdrawn
-
2006
- 2006-11-22 ZA ZA200804163A patent/ZA200804163B/xx unknown
- 2006-11-22 BR BRPI0618847-8A patent/BRPI0618847A2/pt not_active IP Right Cessation
- 2006-11-22 EP EP06818729A patent/EP1973571A1/en not_active Withdrawn
- 2006-11-22 EA EA200801411A patent/EA200801411A1/xx unknown
- 2006-11-22 CN CNA2006800515675A patent/CN101360514A/zh active Pending
- 2006-11-22 JP JP2008541631A patent/JP5249041B2/ja not_active Expired - Fee Related
- 2006-11-22 WO PCT/EP2006/011182 patent/WO2007059931A1/en active Application Filing
- 2006-11-22 AU AU2006316791A patent/AU2006316791B2/en not_active Ceased
- 2006-11-22 CA CA002628736A patent/CA2628736A1/en not_active Abandoned
- 2006-11-22 KR KR1020087015145A patent/KR20080069267A/ko not_active Application Discontinuation
- 2006-11-22 US US12/093,865 patent/US8119689B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ZA200804163B (en) | 2009-10-28 |
| CN101360514A (zh) | 2009-02-04 |
| US8119689B2 (en) | 2012-02-21 |
| WO2007059931A8 (en) | 2007-07-19 |
| EP1787660A1 (en) | 2007-05-23 |
| WO2007059931A1 (en) | 2007-05-31 |
| US20090017106A1 (en) | 2009-01-15 |
| BRPI0618847A2 (pt) | 2011-10-04 |
| AU2006316791A1 (en) | 2007-05-31 |
| KR20080069267A (ko) | 2008-07-25 |
| CA2628736A1 (en) | 2007-05-31 |
| JP2009517350A (ja) | 2009-04-30 |
| JP5249041B2 (ja) | 2013-07-31 |
| EP1973571A1 (en) | 2008-10-01 |
| AU2006316791B2 (en) | 2012-07-12 |
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