EA200700208A1 - Новая псевдополиморфная форма деслоратадина, образованная с диоксидом углерода - Google Patents

Новая псевдополиморфная форма деслоратадина, образованная с диоксидом углерода

Info

Publication number
EA200700208A1
EA200700208A1 EA200700208A EA200700208A EA200700208A1 EA 200700208 A1 EA200700208 A1 EA 200700208A1 EA 200700208 A EA200700208 A EA 200700208A EA 200700208 A EA200700208 A EA 200700208A EA 200700208 A1 EA200700208 A1 EA 200700208A1
Authority
EA
Eurasian Patent Office
Prior art keywords
desloratadine
carbon dioxide
formula
pseudopolymorph form
new pseudopolymorph
Prior art date
Application number
EA200700208A
Other languages
English (en)
Other versions
EA011894B1 (ru
Inventor
Тибор Мезеи
Дьюла Шимиг
Дьюла Лукач
Марта Порч-Маккаи
Балаж Вольк
Эникё Мольнар
Валерия Хофманне Фекете
Жужанна Сент-Кирайи
Original Assignee
Эгиш Дьёдьсердьяр Нирт.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from HU0401373A external-priority patent/HU0401373D0/hu
Priority claimed from HU0500664A external-priority patent/HU226951B1/hu
Application filed by Эгиш Дьёдьсердьяр Нирт. filed Critical Эгиш Дьёдьсердьяр Нирт.
Publication of EA200700208A1 publication Critical patent/EA200700208A1/ru
Publication of EA011894B1 publication Critical patent/EA011894B1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Dairy Products (AREA)
  • Grain Derivatives (AREA)

Abstract

Псевдополиморфная форма деслоратадина, образованная с диоксидом углерода, формулы (I) обладает полезным противоаллергическим действием и ее можно применять в качестве фармацевтически активного вещества. Настоящее изобретение также относится к получению высокочистого деслоратадина. Настоящее изобретение также относится к применению псевдополиморфной формы деслоратадина формулы (I) для получения солей деслоратадина формулы (VI) (где Х обозначает анион и n обозначает 1 или 2).
EA200700208A 2004-07-07 2005-07-07 Новая псевдополиморфная форма деслоратадина, образованная с диоксидом углерода EA011894B1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
HU0401373A HU0401373D0 (en) 2004-07-07 2004-07-07 Pseudopolimorphic form of desloratadine with carbondioxide
HU0500664A HU226951B1 (en) 2005-07-06 2005-07-06 Pseudopolimorphic form of desloratadine with carbon dioxide, process for its preparation and its use
PCT/HU2005/000073 WO2006003479A2 (en) 2004-07-07 2005-07-07 New pseudopolymorph of desloratadine formed with carbon dioxide

Publications (2)

Publication Number Publication Date
EA200700208A1 true EA200700208A1 (ru) 2007-08-31
EA011894B1 EA011894B1 (ru) 2009-06-30

Family

ID=89986128

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200700208A EA011894B1 (ru) 2004-07-07 2005-07-07 Новая псевдополиморфная форма деслоратадина, образованная с диоксидом углерода

Country Status (9)

Country Link
EP (1) EP1817307A2 (ru)
BG (1) BG109814A (ru)
CZ (1) CZ200798A3 (ru)
EA (1) EA011894B1 (ru)
HR (1) HRP20070025A2 (ru)
PL (1) PL381813A1 (ru)
RS (1) RS20070008A (ru)
SK (1) SK50112007A3 (ru)
WO (1) WO2006003479A2 (ru)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU230417B1 (hu) * 2006-10-26 2016-05-30 Egis Gyógyszergyár Zrt Eljárás desloratadine szén-dioxiddal képezett adduktjának előállítására
CN103755682A (zh) * 2013-12-30 2014-04-30 山东达因海洋生物制药股份有限公司 一种地氯雷他定新晶型及制备方法
WO2016024249A1 (en) * 2014-08-14 2016-02-18 Sun Pharmaceutical Industries Limited Crystalline forms of palbociclib
CN104610225B (zh) * 2014-12-29 2017-02-01 广东九明制药有限公司 一种地氯雷他定的制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61501205A (ja) * 1984-02-15 1986-06-19 シェリング・コ−ポレ−ション ８↓−クロル↓−６，１１↓−ジヒドロ↓−１１↓−（４↓−ピペリジリデン）↓−５Ｈ↓−ベンゾ〔５，６〕シクロヘプタ〔１，２−ｂ〕ピリジンおよびその塩、これらの化合物の製造方法、ならびにこれらの化合物を含有する医薬組成物
US5595997A (en) * 1994-12-30 1997-01-21 Sepracor Inc. Methods and compositions for treating allergic rhinitis and other disorders using descarboethoxyloratadine
UA62976C2 (en) * 1997-07-02 2004-01-15 Schering Corp Polymorphs of 8-chloro-6,11-dihydro-11-(4-piperidylidene)-5h-benzo[5,6]cyclohepta[1,2-b]pyridine
HU226998B1 (en) * 2000-11-23 2010-04-28 Richter Gedeon Nyrt Desloratadine hemisulphate, process for the preparation thereof and pharmaceutical compositions containing the same
WO2004012738A1 (en) * 2002-08-05 2004-02-12 Sandoz Ag Novel salt and polymorphs of desloratadine hemifumarate
EP1542986B1 (en) * 2002-09-24 2007-01-24 Morepen Laboratories Ltd. Process for the production of desloratadine

Also Published As

Publication number Publication date
SK50112007A3 (sk) 2007-07-06
CZ200798A3 (cs) 2007-06-20
EA011894B1 (ru) 2009-06-30
HRP20070025A2 (en) 2008-11-30
BG109814A (bg) 2008-04-30
RS20070008A (en) 2008-11-28
EP1817307A2 (en) 2007-08-15
PL381813A1 (pl) 2007-07-23
WO2006003479A2 (en) 2006-01-12
WO2006003479A3 (en) 2006-06-08

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM RU