EA200500449A1 - Способ выявления риска развития у субъекта заболевания, связанного с кислотой - Google Patents

Способ выявления риска развития у субъекта заболевания, связанного с кислотой

Info

Publication number
EA200500449A1
EA200500449A1 EA200500449A EA200500449A EA200500449A1 EA 200500449 A1 EA200500449 A1 EA 200500449A1 EA 200500449 A EA200500449 A EA 200500449A EA 200500449 A EA200500449 A EA 200500449A EA 200500449 A1 EA200500449 A1 EA 200500449A1
Authority
EA
Eurasian Patent Office
Prior art keywords
value
marker
cut
pepsinogen
risk
Prior art date
Application number
EA200500449A
Other languages
English (en)
Other versions
EA007003B1 (ru
Inventor
Осмо Суованиеми
Матти Хяркенен
Пентти Сиппонен
Original Assignee
Биохит Оий
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Биохит Оий filed Critical Биохит Оий
Publication of EA200500449A1 publication Critical patent/EA200500449A1/ru
Publication of EA007003B1 publication Critical patent/EA007003B1/ru

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G01N33/56922—Campylobacter
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/205—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Campylobacter (G)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/575—Hormones
    • G01N2333/595—Gastrins; Cholecystokinins [CCK]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Настоящее изобретение относится к способу выявления риска развития заболевания, связанного с желудочной кислотой, у субъекта, основанному на изучении объектов анализа пепсиногена I, гастрина-17 в состоянии натощак и маркера инфекции Helicobacter pylori (Hp-маркера); указанный способ включает выбор пороговой величины для пепсиногена I, гастрина-17 в состоянии натощак и Hp-маркера, определение концентрации пепсиногена I, гастрина-17 в состоянии натощак и концентрации или присутствия Hp-маркера в образце, взятом у указанного субъекта, и сравнение определенных таким способом концентраций с выбранными пороговыми величинами, в результате чего величина пепсиногена I, равная или превышающая его соответствующую пороговую величину, в комбинации с величиной Hp-маркера менее его соответствующей пороговой величины и величиной гастрина-17 в состоянии натощак, равной или менее его пороговой величины, является показательной в отношении повышенного риска развития заболевания, связанного с желудочной кислотой, у указанного субъекта.Международная заявка была опубликована вместе с отчетом о международном поиске.
EA200500449A 2002-09-06 2003-09-05 Способ выявления риска развития у субъекта заболевания, связанного с кислотой EA007003B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI20021598A FI119571B (fi) 2002-09-06 2002-09-06 Menetelmä esofagiitin tai Barrettin ruokatorven riskin osoittamiseksi yksilöllä
PCT/FI2003/000653 WO2004023148A1 (en) 2002-09-06 2003-09-05 Method for detecting a risk of acid related disease in an individual

Publications (2)

Publication Number Publication Date
EA200500449A1 true EA200500449A1 (ru) 2005-08-25
EA007003B1 EA007003B1 (ru) 2006-06-30

Family

ID=8564544

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200500449A EA007003B1 (ru) 2002-09-06 2003-09-05 Способ выявления риска развития у субъекта заболевания, связанного с кислотой

Country Status (10)

Country Link
EP (1) EP1552311B1 (ru)
JP (1) JP4261481B2 (ru)
KR (1) KR101108282B1 (ru)
CN (1) CN1682115A (ru)
AT (1) ATE414282T1 (ru)
AU (1) AU2003260530A1 (ru)
DE (1) DE60324698D1 (ru)
EA (1) EA007003B1 (ru)
FI (1) FI119571B (ru)
WO (1) WO2004023148A1 (ru)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2441228A1 (en) 2001-03-23 2002-10-03 Aphton Corporation Combination treatment of pancreatic cancer
US20090191232A1 (en) 2001-05-04 2009-07-30 Gevas Philip C Combination therapy for the treatment of tumors
CA2520010C (en) 2003-03-28 2012-07-10 Aphton Corporation Gastrin hormone immunoassays
FI119572B (fi) * 2004-03-05 2008-12-31 Biohit Oyj Menetelmä vatsan limakalvon tilan ennustamiseksi
JP2008513536A (ja) 2004-09-22 2008-05-01 レセプター バイオロジックス インコーポレイテッド プロガストリンに対するモノクローナル抗体
FI20060501L (fi) * 2006-05-22 2007-11-23 Biohit Oyj Koostumus ja menetelmä asetaldehydin sitomiseksi vatsassa
EP2585957A4 (en) * 2010-06-24 2014-12-24 Valtion Teknillinen STATE DEDUCTION IN A HETEROGENEOUS SYSTEM
CN113514647A (zh) * 2014-06-13 2021-10-19 拜奥希特公司 胃泌素-17作为具有增加的数种相关后发病风险的萎缩性胃炎的生物标志物的用途
CA3066756A1 (en) 2017-06-15 2018-12-20 Cancer Advances Inc. Compositions and methods for inducing humoral and cellular immunities against tumors and cancer
KR102637908B1 (ko) * 2018-12-28 2024-02-20 씨제이제일제당 (주) 헬리코박터 파일로리 연관 질환에 대한 유전자 마커

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI118653B (fi) * 1999-04-30 2008-01-31 Biohit Oyj Menetelmä peptisen haavan riskin määrittämiseksi
FI20010019A (fi) * 2001-01-05 2002-07-06 Biohit Oyj Menetelmä atrofisen diagnostisoimiseksi

Also Published As

Publication number Publication date
CN1682115A (zh) 2005-10-12
EP1552311A1 (en) 2005-07-13
FI20021598A (fi) 2004-03-07
WO2004023148A1 (en) 2004-03-18
EP1552311B1 (en) 2008-11-12
EA007003B1 (ru) 2006-06-30
FI20021598A0 (fi) 2002-09-06
AU2003260530A1 (en) 2004-03-29
JP2005538348A (ja) 2005-12-15
KR101108282B1 (ko) 2012-01-31
JP4261481B2 (ja) 2009-04-30
ATE414282T1 (de) 2008-11-15
KR20050057220A (ko) 2005-06-16
DE60324698D1 (de) 2008-12-24
FI119571B (fi) 2008-12-31

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ KZ KG MD TJ TM

MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): BY