EA200401028A1 - Ядерный магнитный резонанс, измеряемый с помощью сверхпроводящего квантового интерференционного датчика, и формирование изображения с помощью магнитного резонанса при сверхслабых полях - Google Patents

Ядерный магнитный резонанс, измеряемый с помощью сверхпроводящего квантового интерференционного датчика, и формирование изображения с помощью магнитного резонанса при сверхслабых полях

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Publication number
EA200401028A1
EA200401028A1 EA200401028A EA200401028A EA200401028A1 EA 200401028 A1 EA200401028 A1 EA 200401028A1 EA 200401028 A EA200401028 A EA 200401028A EA 200401028 A EA200401028 A EA 200401028A EA 200401028 A1 EA200401028 A1 EA 200401028A1
Authority
EA
Eurasian Patent Office
Prior art keywords
magnetic resonance
fields
nmr
measured
super
Prior art date
Application number
EA200401028A
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English (en)
Other versions
EA006832B1 (ru
Inventor
Джон Кларк
Роберт МакДермот
Александр Пайнес
Андреас Хайнц Трабезингер
Original Assignee
Те Риджентс Оф Те Юниверсити Оф Калифорния
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Те Риджентс Оф Те Юниверсити Оф Калифорния filed Critical Те Риджентс Оф Те Юниверсити Оф Калифорния
Publication of EA200401028A1 publication Critical patent/EA200401028A1/ru
Publication of EA006832B1 publication Critical patent/EA006832B1/ru

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/28—Details of apparatus provided for in groups G01R33/44 - G01R33/64
    • G01R33/32—Excitation or detection systems, e.g. using radio frequency signals
    • G01R33/323—Detection of MR without the use of RF or microwaves, e.g. force-detected MR, thermally detected MR, MR detection via electrical conductivity, optically detected MR
    • G01R33/326—Detection of MR without the use of RF or microwaves, e.g. force-detected MR, thermally detected MR, MR detection via electrical conductivity, optically detected MR involving a SQUID
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/02—Measuring direction or magnitude of magnetic fields or magnetic flux
    • G01R33/035—Measuring direction or magnitude of magnetic fields or magnetic flux using superconductive devices
    • G01R33/0354—SQUIDS
    • G01R33/0356—SQUIDS with flux feedback
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/445—MR involving a non-standard magnetic field B0, e.g. of low magnitude as in the earth's magnetic field or in nanoTesla spectroscopy, comprising a polarizing magnetic field for pre-polarisation, B0 with a temporal variation of its magnitude or direction such as field cycling of B0 or rotation of the direction of B0, or spatially inhomogeneous B0 like in fringe-field MR or in stray-field imaging

Landscapes

  • Physics & Mathematics (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • General Physics & Mathematics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Measuring Magnetic Variables (AREA)

Abstract

Сигналы ядерного магнитного резонанса (ЯМР) измеряют в полях с силой в несколько микротесла. За предварительной поляризацией в полях с силой в несколько миллитесла следует измерение с помощью ненастроенного магнитометра с использованием сверхпроводящего квантового интерференционного датчика (Сквид). Поскольку чувствительность Сквида не зависит от частоты, то одновременно улучшается как отношение сигнала к шуму, так и спектральное разрешение при измерении сигнала ЯМР в экстремально слабых магнитных полях, где линии ЯМР становятся очень узкими даже в сильно неоднородных измерительных полях. MRI в сверхслабых магнитных полях основывается на ЯМР в сверхслабых полях. Прикладывают градиентные магнитные поля и создают изображения из измеренных сигналов ЯМР.Отчет о международном поиске был опубликован 2003.11.06.
EA200401028A 2002-02-06 2003-02-06 Ядерный магнитный резонанс, измеряемый с помощью сверхпроводящего квантового интерференционного датчика, и формирование изображения с помощью магнитного резонанса при сверхслабых полях EA006832B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US35557702P 2002-02-06 2002-02-06
PCT/US2003/003712 WO2003067267A2 (en) 2002-02-06 2003-02-06 Squid detected nmr and mri at ultralow fields

Publications (2)

Publication Number Publication Date
EA200401028A1 true EA200401028A1 (ru) 2005-04-28
EA006832B1 EA006832B1 (ru) 2006-04-28

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
EA200401028A EA006832B1 (ru) 2002-02-06 2003-02-06 Ядерный магнитный резонанс, измеряемый с помощью сверхпроводящего квантового интерференционного датчика, и формирование изображения с помощью магнитного резонанса при сверхслабых полях

Country Status (12)

Country Link
US (5) US6885192B2 (ru)
EP (1) EP1474707B1 (ru)
CN (1) CN1287160C (ru)
AP (1) AP2004003127A0 (ru)
AU (1) AU2003210906B2 (ru)
CA (1) CA2478466C (ru)
EA (1) EA006832B1 (ru)
IL (1) IL163669A0 (ru)
MX (1) MXPA04008593A (ru)
NZ (1) NZ534963A (ru)
WO (1) WO2003067267A2 (ru)
ZA (1) ZA200406984B (ru)

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AU2003210906A1 (en) 2003-09-02
US20070018643A1 (en) 2007-01-25
CN1643403A (zh) 2005-07-20
US20040027125A1 (en) 2004-02-12
US7053610B2 (en) 2006-05-30
WO2003067267A3 (en) 2003-11-06
NZ534963A (en) 2006-02-24
US20080074113A1 (en) 2008-03-27
US6885192B2 (en) 2005-04-26
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US20060176054A1 (en) 2006-08-10
CN1287160C (zh) 2006-11-29
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CA2478466C (en) 2013-09-17
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US7218104B2 (en) 2007-05-15
US20050134262A1 (en) 2005-06-23
US7466132B2 (en) 2008-12-16
AP2004003127A0 (en) 2004-09-30
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EP1474707B1 (en) 2012-07-18
IL163669A0 (en) 2005-12-18
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