EA200000532A3 - НОВЫЕ СОЕДИНЕНИЯ 7-ОКСО-2,3,7,14-ТЕТРАГИДРО-1H-БЕНЗО[b]-ПИРАНО [3,2-h]АКРИДИНКАРБОКСИЛАТА, СПОСОБ ИХ ПОЛУЧЕНИЯ И СОДЕРЖАЩИЕ ИХ ФАРМАЦЕВТИЧЕСКИЕ КОМПОЗИЦИИ - Google Patents

НОВЫЕ СОЕДИНЕНИЯ 7-ОКСО-2,3,7,14-ТЕТРАГИДРО-1H-БЕНЗО[b]-ПИРАНО [3,2-h]АКРИДИНКАРБОКСИЛАТА, СПОСОБ ИХ ПОЛУЧЕНИЯ И СОДЕРЖАЩИЕ ИХ ФАРМАЦЕВТИЧЕСКИЕ КОМПОЗИЦИИ

Info

Publication number
EA200000532A3
EA200000532A3 EA200000532A EA200000532A EA200000532A3 EA 200000532 A3 EA200000532 A3 EA 200000532A3 EA 200000532 A EA200000532 A EA 200000532A EA 200000532 A EA200000532 A EA 200000532A EA 200000532 A3 EA200000532 A3 EA 200000532A3
Authority
EA
Eurasian Patent Office
Prior art keywords
group
tetrehydro
pyrano
benzo
oxo
Prior art date
Application number
EA200000532A
Other languages
English (en)
Other versions
EA003361B1 (ru
EA200000532A2 (ru
Inventor
Мишель Кош
Франсуа Тиллекэн
Сильви Мишель
Ганем Атасси
Ален Пьер
Пьер Ренар
Брюно Пфеффер
Original Assignee
Адир Э Компани
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Адир Э Компани filed Critical Адир Э Компани
Publication of EA200000532A2 publication Critical patent/EA200000532A2/ru
Publication of EA200000532A3 publication Critical patent/EA200000532A3/ru
Publication of EA003361B1 publication Critical patent/EA003361B1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Abstract

(57) Соединения формулы (I)где Х и Y представляют атом водорода, атом галогена или гидрокси, меркапто, циано, нитро, алкильную, алкокси, тригалогеналкильную, необязательно замещенную амино, метилендиокси- или этилендиоксигруппу,Rпредставляет атом водорода или алкильную группу,Rпредставляет атом водорода или гидрокси, алкильную, алкокси, алкилкарбонилокси или необязательно замещенную аминогруппу,Rи Rпредставляют атом водорода или алкильную группу,Rи Rпредставляют группу формулы -O-CO-U-V, где U и V такие как определено в описании, или группу Z, как определено в описании, причем следует понимать, что, по меньшей мере, один из Rи Rпредставляет группу формулы -O-CO-U-V,их изомеры, N-оксиды и аддитивные соли их с фармацевтически приемлемой кислотой или основанием. Лекарственные средства.
EA200000532A 1999-06-16 2000-06-15 НОВЫЕ СОЕДИНЕНИЯ 7-ОКСО-2,3,7,14-ТЕТРАГИДРО-1H-БЕНЗО[b]-ПИРАНО[3,2-h]АКРИДИНКАРБОКСИЛАТА И СОДЕРЖАЩИЕ ИХ ФАРМАЦЕВТИЧЕСКИЕ КОМПОЗИЦИИ EA003361B1 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9907611A FR2795071B1 (fr) 1999-06-16 1999-06-16 Nouveaux derives de carboxylate de 7-oxo-2,3,7,14- tetrahydro-1h-benzo[b]pyrano[3,2,h] acridine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (3)

Publication Number Publication Date
EA200000532A2 EA200000532A2 (ru) 2000-12-25
EA200000532A3 true EA200000532A3 (ru) 2001-02-26
EA003361B1 EA003361B1 (ru) 2003-04-24

Family

ID=9546864

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200000532A EA003361B1 (ru) 1999-06-16 2000-06-15 НОВЫЕ СОЕДИНЕНИЯ 7-ОКСО-2,3,7,14-ТЕТРАГИДРО-1H-БЕНЗО[b]-ПИРАНО[3,2-h]АКРИДИНКАРБОКСИЛАТА И СОДЕРЖАЩИЕ ИХ ФАРМАЦЕВТИЧЕСКИЕ КОМПОЗИЦИИ

Country Status (22)

Country Link
US (1) US6503919B1 (ru)
EP (1) EP1061081B1 (ru)
JP (1) JP3364473B2 (ru)
KR (1) KR100433706B1 (ru)
CN (1) CN1147491C (ru)
AT (1) ATE216392T1 (ru)
AU (1) AU774499B2 (ru)
BR (1) BR0002679A (ru)
CA (1) CA2312409C (ru)
DE (1) DE60000125T2 (ru)
DK (1) DK1061081T3 (ru)
EA (1) EA003361B1 (ru)
ES (1) ES2174803T3 (ru)
FR (1) FR2795071B1 (ru)
HK (1) HK1032783A1 (ru)
HU (1) HUP0002288A3 (ru)
NO (1) NO20002940L (ru)
NZ (1) NZ505184A (ru)
PL (1) PL340788A1 (ru)
PT (1) PT1061081E (ru)
SI (1) SI1061081T1 (ru)
ZA (1) ZA200003035B (ru)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6613917B1 (en) * 2000-03-23 2003-09-02 Allergan, Inc. Amines substituted with a dihydronaphthalenyl, chromenyl, or thiochromenyl group, an aryl or heteroaryl group and an alkyl group, having retinoid-like biological activity
FR2827864B1 (fr) * 2001-07-25 2005-09-16 Servier Lab Nouveaux derives de benzo[b]pyrano[3,2-h]acridin-7-one, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2856687B1 (fr) * 2003-06-25 2005-09-16 Servier Lab Nouveaux derives de benzo[a]pyrano[3,2-h]acridin-7-one, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2879600B1 (fr) 2004-12-22 2007-02-09 Servier Lab Nouveaux derives cinnamates de benzo[b]pyrano[3,2-h]acridin-7-one, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
JP4392502B2 (ja) * 2005-06-10 2010-01-06 国立大学法人 岡山大学 蛍光性アミノ酸誘導体

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9224169D0 (en) * 1992-11-18 1993-01-06 Lilly Industries Ltd Pharmaceutical compounds
EP0599514A3 (en) * 1992-11-18 1994-07-06 Lilly Industries Ltd Pyranoquinoline derivatives as inhibitors of cell proliferation.
US5322283A (en) * 1993-02-22 1994-06-21 Williams Electronics Games, Inc. Rotary ball receptacle for a pinball game
FR2772765B1 (fr) * 1997-12-19 2000-03-17 Adir Nouveaux derives de l'acronycine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Also Published As

Publication number Publication date
HK1032783A1 (en) 2001-08-03
NO20002940D0 (no) 2000-06-08
EP1061081A1 (fr) 2000-12-20
HU0002288D0 (en) 2000-08-28
CA2312409C (fr) 2005-02-15
HUP0002288A3 (en) 2003-11-28
DE60000125D1 (de) 2002-05-23
HUP0002288A2 (hu) 2001-04-28
ATE216392T1 (de) 2002-05-15
KR100433706B1 (ko) 2004-05-31
DK1061081T3 (da) 2002-08-12
CN1279239A (zh) 2001-01-10
JP3364473B2 (ja) 2003-01-08
AU4089800A (en) 2000-12-21
EA003361B1 (ru) 2003-04-24
ES2174803T3 (es) 2002-11-16
CA2312409A1 (fr) 2000-12-16
SI1061081T1 (en) 2002-06-30
ZA200003035B (en) 2001-01-11
DE60000125T2 (de) 2002-12-05
CN1147491C (zh) 2004-04-28
NO20002940L (no) 2000-12-18
EA200000532A2 (ru) 2000-12-25
EP1061081B1 (fr) 2002-04-17
JP2001011078A (ja) 2001-01-16
US6503919B1 (en) 2003-01-07
FR2795071B1 (fr) 2001-07-27
PT1061081E (pt) 2002-08-30
NZ505184A (en) 2001-09-28
AU774499B2 (en) 2004-07-01
KR20010029811A (ko) 2001-04-16
PL340788A1 (en) 2000-12-18
BR0002679A (pt) 2001-01-30
FR2795071A1 (fr) 2000-12-22

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM RU