EA199901116A1 - COMPOSITION INCLUDING 5- [4- [2- (N-METHYL-N-2-Pyridyl) -AMINO) ETOXY] BENZYL] TIAZOLIDIN-2,4-DION - Google Patents

COMPOSITION INCLUDING 5- [4- [2- (N-METHYL-N-2-Pyridyl) -AMINO) ETOXY] BENZYL] TIAZOLIDIN-2,4-DION

Info

Publication number
EA199901116A1
EA199901116A1 EA199901116A EA199901116A EA199901116A1 EA 199901116 A1 EA199901116 A1 EA 199901116A1 EA 199901116 A EA199901116 A EA 199901116A EA 199901116 A EA199901116 A EA 199901116A EA 199901116 A1 EA199901116 A1 EA 199901116A1
Authority
EA
Eurasian Patent Office
Prior art keywords
tiazolidin
etoxy
dion
pyridyl
benzyl
Prior art date
Application number
EA199901116A
Other languages
Russian (ru)
Other versions
EA002384B1 (en
Inventor
Джай Пэйтел
Хамиш Росс
Робин Прайс
Джеффри Роджер Грэнетт
Original Assignee
Смитклайн Бичам Плс
Смитклайн Бичам Корпорейшн
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9712851.6A external-priority patent/GB9712851D0/en
Application filed by Смитклайн Бичам Плс, Смитклайн Бичам Корпорейшн filed Critical Смитклайн Бичам Плс
Publication of EA199901116A1 publication Critical patent/EA199901116A1/en
Publication of EA002384B1 publication Critical patent/EA002384B1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

Фармацевтическая композиция, включающая соединение (I), характеризующаяся тем, что она включает от 2 до 12 мг соединения (I) в фармацевтически приемлемой форме и, необязательно, фармацевтически приемлемый носитель для него, применение такой композиции в медицине, способы получения такой композиции и промежуточная композиция, полезная в таком способе.Международная заявка была опубликована вместе с отчетом о международном поиске.A pharmaceutical composition comprising a compound (I), characterized in that it comprises from 2 to 12 mg of compound (I) in a pharmaceutically acceptable form and, optionally, a pharmaceutically acceptable carrier for it, the use of such a composition in medicine, methods for producing such a composition, and intermediate A composition useful in this manner. The international application was published along with an international search report.

EA199901116A 1997-06-05 1998-06-02 Compositions comprising 5-[4-[2-(n-methyl-n-2-pyridyl)amino)etoxy]benzyl]thiazolidine-2,4-dione EA002384B1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9711683.4A GB9711683D0 (en) 1997-06-05 1997-06-05 Composition
GBGB9712851.6A GB9712851D0 (en) 1997-06-18 1997-06-18 Composition
PCT/EP1998/003478 WO1998055122A1 (en) 1997-06-05 1998-06-02 Composition comprising 5-[4-[2-(n-methyl-n-2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2,4-dione

Publications (2)

Publication Number Publication Date
EA199901116A1 true EA199901116A1 (en) 2000-06-26
EA002384B1 EA002384B1 (en) 2002-04-25

Family

ID=26311662

Family Applications (1)

Application Number Title Priority Date Filing Date
EA199901116A EA002384B1 (en) 1997-06-05 1998-06-02 Compositions comprising 5-[4-[2-(n-methyl-n-2-pyridyl)amino)etoxy]benzyl]thiazolidine-2,4-dione

Country Status (29)

Country Link
EP (1) EP0998284A1 (en)
JP (1) JP2001521553A (en)
KR (1) KR20010013410A (en)
CN (3) CN1112926C (en)
AP (1) AP1214A (en)
AR (2) AR008198A1 (en)
AU (1) AU8215098A (en)
BG (1) BG104048A (en)
BR (1) BR9810405A (en)
CA (2) CA2333352A1 (en)
CO (1) CO4940400A1 (en)
DZ (1) DZ2510A1 (en)
EA (1) EA002384B1 (en)
GB (1) GB9711683D0 (en)
HU (1) HUP0004070A3 (en)
ID (1) ID24264A (en)
IL (1) IL133074A0 (en)
MX (1) MXPA99011322A (en)
NO (2) NO995938L (en)
NZ (2) NZ523725A (en)
OA (1) OA11306A (en)
PE (1) PE78899A1 (en)
PL (1) PL337201A1 (en)
SK (1) SK164899A3 (en)
TR (2) TR200002790T2 (en)
TW (1) TW570797B (en)
UY (1) UY25032A1 (en)
WO (1) WO1998055122A1 (en)
ZA (2) ZA984826B (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040248945A1 (en) 1999-04-23 2004-12-09 Smithkline Beecham P.L.C. Thiazolidinedione derivative and its use as antidiabetic
CO5170421A1 (en) 1999-04-23 2002-06-27 Smithkline Beecham Plc NEW MALEICO PHARMACEUTICAL COMPOUND
DZ3155A1 (en) 1999-04-23 2000-11-02 Smithkline Beecham Plc New pharmaceutical composition.
GB0021978D0 (en) 2000-09-07 2000-10-25 Smithkline Beecham Plc Novel pharmaceutical
GB0127805D0 (en) * 2001-11-20 2002-01-09 Smithkline Beecham Plc Pharmaceutical composition
GB0129871D0 (en) * 2001-12-13 2002-02-06 Smithkline Beecham Plc Novel pharmaceutical
GB0129876D0 (en) * 2001-12-13 2002-02-06 Smithkline Beecham Plc Novel pharmaceutical
AU2002350965A1 (en) * 2001-12-13 2003-06-23 Smithkline Beecham Plc Toluenesulfonate hydrates of a thiazolidinedione derivative
GB0130509D0 (en) * 2001-12-20 2002-02-06 Smithkline Beecham Plc Novel pharmaceutical
DE06252444T8 (en) * 2006-05-09 2009-03-19 Teva Pharmaceutical Industries Ltd. 2-N- {5 - [[4- [2- (Methyl-2-pyridinylamino) -ethoxy] -phenyl] -methyl] -2,4-thiazolidinedione-succinic acid, method of preparation and compositions with rosiglitazone maleate
US7435741B2 (en) 2006-05-09 2008-10-14 Teva Pharmaceutical Industries, Ltd. 2-N{5-[[4-[2-(methyl-2-pyridinylamino) ethoxy] phenyl]methyl]-2,4-thiazolidinedione} butanedioic acid, methods of preparation and compositions with rosiglitazone maleate
WO2015008234A1 (en) * 2013-07-17 2015-01-22 Glenmark Pharmaceuticals S.A. Bicyclic heterocyclic compounds as ror gamma modulators

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3856378T2 (en) * 1987-09-04 2000-05-11 Beecham Group Plc Substituted thiazolidinedione derivatives
GB9218830D0 (en) * 1992-09-05 1992-10-21 Smithkline Beecham Plc Novel compounds
EP0777469A1 (en) * 1994-02-10 1997-06-11 Smithkline Beecham Plc Use of insulin sensitisers for treating renal diseases
CN1192683A (en) * 1995-08-10 1998-09-09 沃尼尔·朗伯公司 Method for reducing amount of exogenous insulin administered to a patient having noninsulin-dependent diabetes mellitus
AU7604596A (en) * 1995-11-17 1997-06-11 Warner-Lambert Company A method of treating myotonic dystrophy
NZ314406A (en) * 1996-03-18 2000-12-22 Sankyo Co Treatment or prophylaxis of pancreatitis with a medicament containing an insulin sensitiser including oxazoles and thiazoles
CN1230114A (en) * 1996-07-12 1999-09-29 史密丝克莱恩比彻姆有限公司 Novel treatment of leptine resistance

Also Published As

Publication number Publication date
OA11306A (en) 2003-10-22
IL133074A0 (en) 2001-03-19
BG104048A (en) 2000-07-31
GB9711683D0 (en) 1997-08-06
NZ513922A (en) 2001-09-28
CN1430959A (en) 2003-07-23
TW570797B (en) 2004-01-11
CN1112926C (en) 2003-07-02
BR9810405A (en) 2000-08-29
TR200002790T2 (en) 2001-11-21
KR20010013410A (en) 2001-02-26
NO995938L (en) 2000-02-02
CA2292629C (en) 2004-01-06
TR199902963T2 (en) 2000-02-21
HUP0004070A2 (en) 2002-02-28
ZA9811572B (en) 1999-07-22
AP1214A (en) 2003-10-08
DZ2510A1 (en) 2003-01-25
NO995938D0 (en) 1999-12-03
AR008198A1 (en) 1999-12-29
JP2001521553A (en) 2001-11-06
HUP0004070A3 (en) 2002-03-28
CN1259050A (en) 2000-07-05
NO20040738L (en) 2000-02-02
UY25032A1 (en) 1998-11-26
CO4940400A1 (en) 2000-07-24
AP9901696A0 (en) 1999-12-31
AU8215098A (en) 1998-12-21
CA2292629A1 (en) 1998-12-10
NZ523725A (en) 2004-09-24
AR015120A1 (en) 2001-04-18
ZA984826B (en) 1999-08-03
CN1526391A (en) 2004-09-08
PL337201A1 (en) 2000-08-14
CA2333352A1 (en) 1998-12-10
MXPA99011322A (en) 2004-12-02
ID24264A (en) 2000-07-13
EP0998284A1 (en) 2000-05-10
PE78899A1 (en) 1999-10-22
WO1998055122A1 (en) 1998-12-10
EA002384B1 (en) 2002-04-25
SK164899A3 (en) 2000-11-07

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM RU