EA199800565A1 - Способ и состав для лечения эректильной дисфункции - Google Patents

Способ и состав для лечения эректильной дисфункции

Info

Publication number
EA199800565A1
EA199800565A1 EA199800565A EA199800565A EA199800565A1 EA 199800565 A1 EA199800565 A1 EA 199800565A1 EA 199800565 A EA199800565 A EA 199800565A EA 199800565 A EA199800565 A EA 199800565A EA 199800565 A1 EA199800565 A1 EA 199800565A1
Authority
EA
Eurasian Patent Office
Prior art keywords
treatment
erectile dysfunction
prostaglandin
liposomes
component
Prior art date
Application number
EA199800565A
Other languages
English (en)
Inventor
Джеки Р. Си
Original Assignee
Харвард Сайентифик Корпорейшн
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Харвард Сайентифик Корпорейшн filed Critical Харвард Сайентифик Корпорейшн
Publication of EA199800565A1 publication Critical patent/EA199800565A1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gynecology & Obstetrics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Изобретение относится к лечению эректильной дисфункции и, более конкретно, к внутриканальному (через отверстие) приему липосом, содержащих простагландин, для достижения опухания и твердости. Изобретение предусматривает создание фармацевтических составов и способов лечения эректильной дисфункции. К числу предпочтительных фармацевтических составов относится двухкомпонентная система, причем один компонент содержит липосомы, включающие в себя простагландин, а второй компонент содержит водный раствор возбудителя (активатора), включающий в себя химические средства для контролируемого лизирования липосом с целью высвобождения находящегося в них простагландина. Для лечения эректильной дисфункции два компонента смешиваются вместе с образованием раствора, который затем прикладывается к пенису либо наружно, либо, что предпочтительней, внутриканально для получения удовлетворительной эрекции.Международная заявка была опубликована вместе с отчетом о международном поиске.
EA199800565A 1995-12-15 1996-11-26 Способ и состав для лечения эректильной дисфункции EA199800565A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/573,408 US5718917A (en) 1995-12-15 1995-12-15 PGE-1 containing lyophilized liposomes for use in the treatment of erectile dysfunction
PCT/US1996/018820 WO1997022334A1 (en) 1995-12-15 1996-11-26 Pge-1 containing lyophilized liposomes for use in the treatment of erectile dysfunction

Publications (1)

Publication Number Publication Date
EA199800565A1 true EA199800565A1 (ru) 1999-02-25

Family

ID=24291879

Family Applications (1)

Application Number Title Priority Date Filing Date
EA199800565A EA199800565A1 (ru) 1995-12-15 1996-11-26 Способ и состав для лечения эректильной дисфункции

Country Status (17)

Country Link
US (1) US5718917A (ru)
EP (1) EP0874622A4 (ru)
JP (1) JPH11504945A (ru)
KR (1) KR20000064392A (ru)
CN (1) CN1207671A (ru)
AU (1) AU722555B2 (ru)
BR (1) BR9612040A (ru)
EA (1) EA199800565A1 (ru)
EE (1) EE9800182A (ru)
HU (1) HUP9902094A2 (ru)
IL (1) IL124841A (ru)
IS (1) IS4767A (ru)
NO (1) NO982727L (ru)
PL (1) PL327400A1 (ru)
SK (1) SK80998A3 (ru)
TR (1) TR199801104T2 (ru)
WO (1) WO1997022334A1 (ru)

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US20020004529A1 (en) * 1997-10-20 2002-01-10 Gary W. Neal Methods, compositions, and kits for enhancing female sexual desire and responsiveness
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WO2000051978A1 (en) * 1999-03-01 2000-09-08 Nitromed, Inc. Nitrosated and nitrosylated prostaglandins, compositions and metods of use
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EP1643972A4 (en) * 2003-06-27 2010-01-20 Smithkline Beecham Corp STABILIZED LIPOSOMAL TOPOTECAN COMPOSITION AND METHOD
US9005183B2 (en) * 2007-05-16 2015-04-14 Health Knight, Llc System and method for treating erectile dysfunction
CN101095944B (zh) * 2007-07-10 2012-04-18 上海市肿瘤研究所 一种预防和治疗前列腺炎穴位缓释贴片及其制品、制备方法和用途
CN101912363A (zh) * 2010-07-29 2010-12-15 蔡海德 溶解超滤-喷雾干燥-分子分散包衣-水化制粒-冷冻干燥生产脂质体组合药物
CN102133182A (zh) * 2010-12-30 2011-07-27 北京中海康医药科技发展有限公司 一种依前列醇脂质体及其制备方法
US9962393B1 (en) * 2015-06-21 2018-05-08 Angiosoma Research, Inc. Method for treating vascular disease by administering a liposomal prostaglandin composition

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Also Published As

Publication number Publication date
IS4767A (is) 1998-06-09
KR20000064392A (ko) 2000-11-06
EP0874622A1 (en) 1998-11-04
EE9800182A (et) 1998-12-15
SK80998A3 (en) 1999-01-11
US5718917A (en) 1998-02-17
PL327400A1 (en) 1998-12-07
NO982727D0 (no) 1998-06-12
BR9612040A (pt) 1999-12-28
AU1024297A (en) 1997-07-14
IL124841A0 (en) 1999-01-26
NO982727L (no) 1998-08-17
IL124841A (en) 2001-01-28
CN1207671A (zh) 1999-02-10
EP0874622A4 (en) 1999-02-10
WO1997022334A1 (en) 1997-06-26
JPH11504945A (ja) 1999-05-11
TR199801104T2 (xx) 1998-10-21
HUP9902094A2 (hu) 1999-10-28
AU722555B2 (en) 2000-08-03

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