EA039412B1 - 5-ht2c рецепторные агонисты и композиции и способы применения - Google Patents

Info

Publication number

EA039412B1

EA039412B1 EA201890402A EA201890402A EA039412B1 EA 039412 B1 EA039412 B1 EA 039412B1 EA 201890402 A EA201890402 A EA 201890402A EA 201890402 A EA201890402 A EA 201890402A EA 039412 B1 EA039412 B1 EA 039412B1

Authority

EA

Eurasian Patent Office

Prior art keywords

compound

azepine

formula

cyclopropane

naphtho

Prior art date

2015-07-31

Links

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• Global Dossier
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• 238000000034 method Methods 0.000 title claims abstract description 89
• 239000000203 mixture Substances 0.000 title claims description 263
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• 108010072553 5-HT2C Serotonin Receptor Proteins 0.000 title abstract description 19
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• 239000000018 receptor agonist Substances 0.000 title description 17
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• 239000000460 chlorine Substances 0.000 claims description 169
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• 238000002360 preparation method Methods 0.000 claims description 113
• 150000003839 salts Chemical class 0.000 claims description 60
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• 125000002837 carbocyclic group Chemical group 0.000 claims description 40
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• 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims description 27
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• 150000001721 carbon Chemical group 0.000 claims description 23
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• KSAVQLQVUXSOCR-UHFFFAOYSA-M sodium lauroyl sarcosinate Chemical compound [Na+].CCCCCCCCCCCC(=O)N(C)CC([O-])=O KSAVQLQVUXSOCR-UHFFFAOYSA-M 0.000 claims description 3
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