EA037895B1 - Твердые фармацевтические композиции антагонистов рецепторов андрогенов - Google Patents
Твердые фармацевтические композиции антагонистов рецепторов андрогенов Download PDFInfo
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- EA037895B1 EA037895B1 EA201691568A EA201691568A EA037895B1 EA 037895 B1 EA037895 B1 EA 037895B1 EA 201691568 A EA201691568 A EA 201691568A EA 201691568 A EA201691568 A EA 201691568A EA 037895 B1 EA037895 B1 EA 037895B1
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- EA
- Eurasian Patent Office
- Prior art keywords
- compound
- formula
- solid
- enzalutamide
- pharmaceutical composition
- Prior art date
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| LT3305285T (lt) | 2012-09-26 | 2020-12-10 | Aragon Pharmaceuticals, Inc. | Anti-androgenai, skirti gydyti nametastazavusį kastracijai atsparų prostatos vėžį |
| PL3226843T3 (pl) * | 2014-12-05 | 2021-12-13 | Aragon Pharmaceuticals, Inc. | Kompozycje przeciwnowotworowe |
| CN114886852A (zh) | 2014-12-05 | 2022-08-12 | 阿拉贡药品公司 | 抗癌组合物 |
| CA2969661C (en) * | 2014-12-05 | 2023-04-25 | Aragon Pharmaceuticals, Inc. | Anticancer compositions |
| MX2018014846A (es) * | 2016-06-03 | 2019-03-14 | Aragon Pharmaceuticals Inc | Composiciones antineoplasicas. |
| WO2017221144A1 (en) * | 2016-06-20 | 2017-12-28 | Dr. Reddy's Laboratories Limited | Process for the preparation of elagolix sodium and its polymorph |
| CN110023297A (zh) * | 2016-07-08 | 2019-07-16 | 詹森药业有限公司 | 作为雄性激素受体拮抗剂的取代的乙内酰脲和硫代己内酰脲衍生物 |
| EP3500310A1 (en) | 2016-08-20 | 2019-06-26 | FTF Pharma Private Limited | Pharmaceutical composition comprising an androgen receptor inhibitor |
| KR102684756B1 (ko) * | 2017-04-28 | 2024-07-15 | 아스텔라스세이야쿠 가부시키가이샤 | 엔잘루타미드를 함유하는 경구 투여용 의약 조성물 |
| WO2019008426A1 (en) * | 2017-07-04 | 2019-01-10 | Bdr Pharmaceuticals International Private Limited | NOVEL ENZALUTAMIDE ORAL GALENIC FORM COMPOSITION AND METHOD OF MANUFACTURING THE SAME |
| WO2019016747A1 (en) * | 2017-07-20 | 2019-01-24 | Dr. Reddy's Laboratories Limited | AMORPHOUS SOLID DISPERSIONS OF APALUTAMIDE AND PROCESS FOR THEIR PREPARATION |
| RU2020109948A (ru) * | 2017-08-08 | 2021-09-10 | Др. Редди'З Лабораториз Лимитед | Экструдированные композиции энзалутамида |
| CZ2018234A3 (cs) | 2018-05-21 | 2019-12-04 | Zentiva Ks | Zvýšení rozpustnosti a biodostupnosti enzalutamidu |
| CN108815129A (zh) * | 2018-07-12 | 2018-11-16 | 天津双硕医药科技有限公司 | 一种恩杂鲁胺纳米晶体口服固体药物组合物 |
| ES2943492T3 (es) | 2018-11-30 | 2023-06-13 | Chemocentryx Inc | Formulación de cápsulas |
| JP2022533463A (ja) * | 2019-05-23 | 2022-07-22 | ヘルム・アクチエンゲゼルシャフト | エンザルタミドを含むナノ粒子 |
| EP4037659B1 (en) | 2019-10-03 | 2025-11-19 | Synthon BV | Pharmaceutical composition comprising enzalutamide |
| EP3811932A1 (en) | 2019-10-22 | 2021-04-28 | Zentiva K.S. | Dosage form of apalutamide |
| US20240207239A1 (en) * | 2021-02-06 | 2024-06-27 | Sunshine Lake Pharma Co., Ltd. | Composition and preparation method therefor |
| WO2024127361A1 (en) | 2022-12-16 | 2024-06-20 | Ferring B.V. | Enzalutamide nanocrystals, methods and compositions |
| WO2025052925A1 (ja) * | 2023-09-08 | 2025-03-13 | 沢井製薬株式会社 | エンザルタミド固体分散体及びその製造方法、並びにエンザルタミド含有製剤及びその製造方法 |
| WO2025125565A1 (en) | 2023-12-13 | 2025-06-19 | Krka, D.D., Novo Mesto | Tablet comprising enzalutamide |
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| WO2007127010A2 (en) * | 2006-03-29 | 2007-11-08 | The Regents Of The University Of California | Diarylthiohydantoin compounds |
| WO2011103202A2 (en) * | 2010-02-16 | 2011-08-25 | Aragon Pharmaceuticals, Inc. | Androgen receptor modulators and uses thereof |
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| CA2448825C (en) * | 2001-06-22 | 2009-08-11 | Pfizer Products Inc. | Pharmaceutical compositions of adsorbates of amorphous drug |
| EP2877599B1 (en) * | 2012-07-27 | 2019-10-23 | Aragon Pharmaceuticals, Inc. | Methods and compositions for determining resistance to androgen receptor therapy |
| DK3725778T3 (da) * | 2012-09-11 | 2021-09-20 | Medivation Prostate Therapeutics Llc | Formuleringer af enzalutamid |
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2019
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2020
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| WO2007127010A2 (en) * | 2006-03-29 | 2007-11-08 | The Regents Of The University Of California | Diarylthiohydantoin compounds |
| WO2011103202A2 (en) * | 2010-02-16 | 2011-08-25 | Aragon Pharmaceuticals, Inc. | Androgen receptor modulators and uses thereof |
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|---|---|
| AU2015215000B2 (en) | 2017-10-19 |
| EA201691568A1 (ru) | 2017-01-30 |
| EA201891397A1 (ru) | 2019-03-29 |
| MX2016010216A (es) | 2016-11-15 |
| KR20200015830A (ko) | 2020-02-12 |
| JP2017507928A (ja) | 2017-03-23 |
| CN112402360A (zh) | 2021-02-26 |
| AU2015215000A1 (en) | 2016-09-15 |
| JP6666254B2 (ja) | 2020-03-13 |
| CA2940984A1 (en) | 2015-08-13 |
| US20160346207A1 (en) | 2016-12-01 |
| JP6934932B2 (ja) | 2021-09-15 |
| MX386859B (es) | 2025-03-19 |
| CN106102716A (zh) | 2016-11-09 |
| JP2020090505A (ja) | 2020-06-11 |
| EP3102183A1 (en) | 2016-12-14 |
| WO2015118015A1 (en) | 2015-08-13 |
| US20200163882A1 (en) | 2020-05-28 |
| KR20160113294A (ko) | 2016-09-28 |
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