EA036889B1 - Биомаркеры ответа на ингибиторы ezh2 - Google Patents
Биомаркеры ответа на ингибиторы ezh2 Download PDFInfo
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- EA036889B1 EA036889B1 EA201692497A EA201692497A EA036889B1 EA 036889 B1 EA036889 B1 EA 036889B1 EA 201692497 A EA201692497 A EA 201692497A EA 201692497 A EA201692497 A EA 201692497A EA 036889 B1 EA036889 B1 EA 036889B1
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- Eurasian Patent Office
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- bap1
- biomarker
- ezh2
- cancer
- expression
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| MX2018002344A (es) | 2015-08-24 | 2018-07-06 | Epizyme Inc | Metodo para tratar el cancer. |
| TW201718598A (zh) | 2015-08-27 | 2017-06-01 | 美國禮來大藥廠 | Ｅｚｈ２抑制劑 |
| US12442042B2 (en) | 2016-02-16 | 2025-10-14 | Agency For Science, Technology And Research | Epigenomic profiling reveals the somatic promoter landscape of primary gastric adenocarcinoma |
| GB201615842D0 (en) * | 2016-09-16 | 2016-11-02 | Ucl Business Plc | Cell death biomarker |
| CN106963765B (zh) * | 2017-03-28 | 2020-04-07 | 上海交通大学医学院附属第九人民医院 | Ezh2抑制剂化合物在制备治疗眼部黑色素瘤的药物中的应用 |
| WO2020247130A1 (en) * | 2019-06-03 | 2020-12-10 | Icahn School Of Medicine At Mount Sinai | Compounds and methods for inhibiting cancers via rest inhibition |
| GB201919219D0 (en) | 2019-12-23 | 2020-02-05 | Otsuka Pharma Co Ltd | Cancer biomarkers |
| CN118161615B (zh) * | 2024-03-19 | 2025-08-12 | 山东大学齐鲁医院 | Phf20抑制剂在制备抗皮肤癌药物中的应用 |
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| WO1999025373A1 (en) * | 1997-11-14 | 1999-05-27 | Millennium Pharmaceuticals, Inc. | Modulation of drug resistance via ubiquitin carboxy-terminal hydrolase |
| WO2012144220A1 (en) * | 2011-04-22 | 2012-10-26 | Oncotherapy Science, Inc. | Ezh2 as target gene for cancer therapy and diagnosis |
| WO2013049770A2 (en) * | 2011-09-30 | 2013-04-04 | Glaxosmithkline Llc | Methods of treating cancer |
| US20140011696A1 (en) * | 2011-02-16 | 2014-01-09 | Thomas Wiesner | Bap1 mutational analysis in determining susceptibility to, prognosis of, and treatment of melanocytic neoplasia |
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| US6218122B1 (en) | 1998-06-19 | 2001-04-17 | Rosetta Inpharmatics, Inc. | Methods of monitoring disease states and therapies using gene expression profiles |
| US6406921B1 (en) | 1998-07-14 | 2002-06-18 | Zyomyx, Incorporated | Protein arrays for high-throughput screening |
| US6271002B1 (en) | 1999-10-04 | 2001-08-07 | Rosetta Inpharmatics, Inc. | RNA amplification method |
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| US7112408B2 (en) | 2001-06-08 | 2006-09-26 | The Brigham And Women's Hospital, Inc. | Detection of ovarian cancer based upon alpha-haptoglobin levels |
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2015
- 2015-06-19 MX MX2016017097A patent/MX384423B/es unknown
- 2015-06-19 CN CN201580044280.9A patent/CN106795561B/zh not_active Expired - Fee Related
- 2015-06-19 EP EP15809484.7A patent/EP3158086B1/en active Active
- 2015-06-19 EA EA201692497A patent/EA036889B1/ru unknown
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- 2015-06-19 BR BR112016029911A patent/BR112016029911A2/pt not_active Application Discontinuation
- 2015-06-19 AU AU2015276899A patent/AU2015276899B2/en not_active Ceased
- 2015-06-19 CA CA2952285A patent/CA2952285A1/en not_active Abandoned
- 2015-06-19 WO PCT/US2015/036677 patent/WO2015196064A1/en not_active Ceased
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- 2015-06-19 ES ES15809484T patent/ES2870096T3/es active Active
- 2015-06-19 JP JP2016573588A patent/JP6684230B2/ja not_active Expired - Fee Related
- 2015-06-19 KR KR1020177001353A patent/KR20170020463A/ko not_active Abandoned
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2016
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- 2016-12-12 ZA ZA2016/08555A patent/ZA201608555B/en unknown
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Also Published As
| Publication number | Publication date |
|---|---|
| AU2015276899A1 (en) | 2017-01-05 |
| JP2017525337A (ja) | 2017-09-07 |
| CN106795561A (zh) | 2017-05-31 |
| EP3158086A4 (en) | 2018-01-10 |
| KR20170020463A (ko) | 2017-02-22 |
| ZA201608555B (en) | 2022-05-25 |
| WO2015196064A1 (en) | 2015-12-23 |
| CA2952285A1 (en) | 2015-12-23 |
| CN106795561B (zh) | 2021-04-16 |
| BR112016029911A2 (pt) | 2017-10-24 |
| JP6684230B2 (ja) | 2020-04-22 |
| AU2015276899B2 (en) | 2021-08-12 |
| EA201692497A1 (ru) | 2017-06-30 |
| IL249443B (en) | 2022-05-01 |
| SG11201610610YA (en) | 2017-01-27 |
| US20170138946A1 (en) | 2017-05-18 |
| ES2870096T3 (es) | 2021-10-26 |
| IL249443A0 (en) | 2017-02-28 |
| MX384423B (es) | 2025-03-14 |
| MX2016017097A (es) | 2017-05-01 |
| EP3158086B1 (en) | 2021-03-24 |
| SG10202007972SA (en) | 2020-10-29 |
| EP3158086A1 (en) | 2017-04-26 |
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