KR20170020463A - Ezh2 저해제에의 반응에 대한 바이오마커 - Google Patents

Ezh2 저해제에의 반응에 대한 바이오마커 Download PDF

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KR20170020463A
KR20170020463A KR1020177001353A KR20177001353A KR20170020463A KR 20170020463 A KR20170020463 A KR 20170020463A KR 1020177001353 A KR1020177001353 A KR 1020177001353A KR 20177001353 A KR20177001353 A KR 20177001353A KR 20170020463 A KR20170020463 A KR 20170020463A
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cancer
bap1
biomarker
expression
ezh2
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Korean (ko)
Inventor
로스 레바인
린제이 라파브
오마르 압델-와합
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메모리얼 슬로안-케터링 캔서 센터
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Publication of KR20170020463A publication Critical patent/KR20170020463A/ko
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    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
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    • A61K31/53751,4-Oxazines, e.g. morpholine
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    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
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    • G01N33/5011Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
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    • G01N2333/91Transferases (2.)
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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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KR1020177001353A 2014-06-19 2015-06-19 Ezh2 저해제에의 반응에 대한 바이오마커 Abandoned KR20170020463A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462014594P 2014-06-19 2014-06-19
US62/014,594 2014-06-19
PCT/US2015/036677 WO2015196064A1 (en) 2014-06-19 2015-06-19 Biomarkers for response to ezh2 inhibitors

Publications (1)

Publication Number Publication Date
KR20170020463A true KR20170020463A (ko) 2017-02-22

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KR1020177001353A Abandoned KR20170020463A (ko) 2014-06-19 2015-06-19 Ezh2 저해제에의 반응에 대한 바이오마커

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Country Link
US (1) US20170138946A1 (enExample)
EP (1) EP3158086B1 (enExample)
JP (1) JP6684230B2 (enExample)
KR (1) KR20170020463A (enExample)
CN (1) CN106795561B (enExample)
AU (1) AU2015276899B2 (enExample)
BR (1) BR112016029911A2 (enExample)
CA (1) CA2952285A1 (enExample)
EA (1) EA036889B1 (enExample)
ES (1) ES2870096T3 (enExample)
IL (1) IL249443B (enExample)
MX (1) MX384423B (enExample)
SG (2) SG10202007972SA (enExample)
WO (1) WO2015196064A1 (enExample)
ZA (1) ZA201608555B (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
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MX376008B (es) 2012-10-15 2025-03-07 Epizyme Inc Inhibidor de ezh2 para usarse en el tratamiento de sarcoma epiteloide.
MX2018002344A (es) 2015-08-24 2018-07-06 Epizyme Inc Metodo para tratar el cancer.
TW201718598A (zh) 2015-08-27 2017-06-01 美國禮來大藥廠 Ezh2抑制劑
US12442042B2 (en) 2016-02-16 2025-10-14 Agency For Science, Technology And Research Epigenomic profiling reveals the somatic promoter landscape of primary gastric adenocarcinoma
GB201615842D0 (en) * 2016-09-16 2016-11-02 Ucl Business Plc Cell death biomarker
CN106963765B (zh) * 2017-03-28 2020-04-07 上海交通大学医学院附属第九人民医院 Ezh2抑制剂化合物在制备治疗眼部黑色素瘤的药物中的应用
WO2020247130A1 (en) * 2019-06-03 2020-12-10 Icahn School Of Medicine At Mount Sinai Compounds and methods for inhibiting cancers via rest inhibition
GB201919219D0 (en) 2019-12-23 2020-02-05 Otsuka Pharma Co Ltd Cancer biomarkers
CN118161615B (zh) * 2024-03-19 2025-08-12 山东大学齐鲁医院 Phf20抑制剂在制备抗皮肤癌药物中的应用

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US5932422A (en) * 1997-11-14 1999-08-03 Millennium Pharmaceuticals, Inc. Modulation of drug resistance via ubiquitin carboxy-terminal hydrolase
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PL2614369T3 (pl) 2010-09-10 2016-08-31 Epizyme Inc Sposób określania przydatności inhibitorów ludzkiego ezh2 w leczeniu
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Publication number Publication date
AU2015276899A1 (en) 2017-01-05
JP2017525337A (ja) 2017-09-07
CN106795561A (zh) 2017-05-31
EP3158086A4 (en) 2018-01-10
ZA201608555B (en) 2022-05-25
WO2015196064A1 (en) 2015-12-23
CA2952285A1 (en) 2015-12-23
CN106795561B (zh) 2021-04-16
BR112016029911A2 (pt) 2017-10-24
JP6684230B2 (ja) 2020-04-22
AU2015276899B2 (en) 2021-08-12
EA201692497A1 (ru) 2017-06-30
EA036889B1 (ru) 2021-01-12
IL249443B (en) 2022-05-01
SG11201610610YA (en) 2017-01-27
US20170138946A1 (en) 2017-05-18
ES2870096T3 (es) 2021-10-26
IL249443A0 (en) 2017-02-28
MX384423B (es) 2025-03-14
MX2016017097A (es) 2017-05-01
EP3158086B1 (en) 2021-03-24
SG10202007972SA (en) 2020-10-29
EP3158086A1 (en) 2017-04-26

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