EA032494B1 - N-КОНЦЕВОЙ Аβ1-15 АНТИГЕННЫЙ ПЕПТИД ДЛЯ ЛЕЧЕНИЯ ИНДИВИДУУМА С СИНДРОМОМ ДАУНА - Google Patents
N-КОНЦЕВОЙ Аβ1-15 АНТИГЕННЫЙ ПЕПТИД ДЛЯ ЛЕЧЕНИЯ ИНДИВИДУУМА С СИНДРОМОМ ДАУНА Download PDFInfo
- Publication number
- EA032494B1 EA032494B1 EA201400376A EA201400376A EA032494B1 EA 032494 B1 EA032494 B1 EA 032494B1 EA 201400376 A EA201400376 A EA 201400376A EA 201400376 A EA201400376 A EA 201400376A EA 032494 B1 EA032494 B1 EA 032494B1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- individual
- particular less
- memory
- mice
- antigenic peptide
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0007—Nervous system antigens; Prions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/10—Peptides having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/385—Haptens or antigens, bound to carriers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6018—Lipids, e.g. in lipopeptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Gastroenterology & Hepatology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| USPCT/US2011/052992 | 2011-09-23 | ||
| PCT/US2012/056728 WO2013044147A1 (en) | 2011-09-23 | 2012-09-21 | Vaccine therapy |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EA201400376A1 EA201400376A1 (ru) | 2014-09-30 |
| EA032494B1 true EA032494B1 (ru) | 2019-06-28 |
Family
ID=47018510
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA201400376A EA032494B1 (ru) | 2011-09-23 | 2012-09-21 | N-КОНЦЕВОЙ Аβ1-15 АНТИГЕННЫЙ ПЕПТИД ДЛЯ ЛЕЧЕНИЯ ИНДИВИДУУМА С СИНДРОМОМ ДАУНА |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US20240270829A1 (enExample) |
| EP (1) | EP2758071B1 (enExample) |
| JP (1) | JP6110861B2 (enExample) |
| KR (3) | KR102129220B1 (enExample) |
| CN (2) | CN104039346A (enExample) |
| AU (1) | AU2012312126B2 (enExample) |
| BR (1) | BR112014006871A2 (enExample) |
| CA (1) | CA2811188C (enExample) |
| DK (1) | DK2758071T3 (enExample) |
| EA (1) | EA032494B1 (enExample) |
| ES (1) | ES2712951T3 (enExample) |
| HU (1) | HUE041277T2 (enExample) |
| IL (1) | IL231564A0 (enExample) |
| MX (1) | MX350928B (enExample) |
| MY (1) | MY169574A (enExample) |
| PH (1) | PH12014500657A1 (enExample) |
| PL (1) | PL2758071T3 (enExample) |
| PT (1) | PT2758071T (enExample) |
| SG (1) | SG11201400795UA (enExample) |
| SI (1) | SI2758071T1 (enExample) |
| TR (1) | TR201901846T4 (enExample) |
| WO (1) | WO2013044147A1 (enExample) |
| ZA (1) | ZA201402071B (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ630542A (en) | 2012-08-16 | 2017-06-30 | Ipierian Inc | Methods of treating a tauopathy |
| US8980270B2 (en) | 2013-01-18 | 2015-03-17 | Ipierian, Inc. | Methods of treating a tauopathy |
| JP2017512751A (ja) | 2014-02-14 | 2017-05-25 | アイピエリアン，インコーポレイティド | タウペプチド、抗タウ抗体、およびそれらの使用方法 |
| CA3118692A1 (en) | 2018-11-06 | 2020-05-14 | Alsatech, Inc. | Cell-based gene therapy for neurodegenerative diseases |
| SG11202112329RA (en) * | 2019-05-21 | 2021-12-30 | Ac Immune Sa | Anti-abeta vaccine therapy |
| KR20250137159A (ko) | 2023-01-26 | 2025-09-17 | 에이씨 이뮨 에스에이 | 항-a베타 백신 요법 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007068411A2 (en) * | 2005-12-12 | 2007-06-21 | Ac Immune S.A. | Therapeutic vaccine |
| WO2010106127A2 (en) * | 2009-03-18 | 2010-09-23 | Ac Immune S.A. | Method for therapeutic use |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR9811401A (pt) | 1997-08-28 | 2000-08-29 | Ajay North America E Som Iodo | Processos para proteger uma substância agrìcola contra pestes que são nocivas para a substância agrìcola e para a proteção de uma substãncia agrìcola, e, composição protetora para substâncias agrìcolas |
| AU2003292936A1 (en) | 2002-12-24 | 2004-07-22 | Neurochem (International) Limited | Therapeutic formulations for the treatment of beta-amyloid related diseases |
| NZ567324A (en) * | 2003-02-01 | 2009-08-28 | Wyeth Corp | Active immunization to generate antibodies to soluble A-beta |
| US8663650B2 (en) | 2003-02-21 | 2014-03-04 | Ac Immune Sa | Methods and compositions comprising supramolecular constructs |
| JP4696079B2 (ja) * | 2003-12-17 | 2011-06-08 | ヤンセン アルツハイマー イミュノセラピー | Ａβ免疫原性ペプチド担体結合物およびそれの製造方法 |
| MX2007000998A (es) * | 2004-07-30 | 2007-07-11 | Rinat Neuroscience Corp | Anticuerpos dirigidos peptido beta-amiloide y procedimientos que usan los mismos. |
| NZ581835A (en) * | 2007-06-12 | 2012-09-28 | Ac Immune Sa | Monoclonal anti beta amyloid antibody |
-
2011
- 2011-09-23 CA CA2811188A patent/CA2811188C/en active Active
- 2011-09-23 KR KR1020197008710A patent/KR102129220B1/ko active Active
- 2011-09-23 KR KR1020137002631A patent/KR20160005380A/ko not_active Ceased
- 2011-09-23 KR KR1020167021791A patent/KR20160099732A/ko not_active Ceased
-
2012
- 2012-09-21 BR BR112014006871A patent/BR112014006871A2/pt not_active Application Discontinuation
- 2012-09-21 EP EP12772616.4A patent/EP2758071B1/en active Active
- 2012-09-21 HU HUE12772616A patent/HUE041277T2/hu unknown
- 2012-09-21 ES ES12772616T patent/ES2712951T3/es active Active
- 2012-09-21 CN CN201280057432.5A patent/CN104039346A/zh active Pending
- 2012-09-21 PT PT12772616T patent/PT2758071T/pt unknown
- 2012-09-21 EA EA201400376A patent/EA032494B1/ru not_active IP Right Cessation
- 2012-09-21 WO PCT/US2012/056728 patent/WO2013044147A1/en not_active Ceased
- 2012-09-21 CN CN201910160828.6A patent/CN109847058A/zh active Pending
- 2012-09-21 JP JP2014532040A patent/JP6110861B2/ja active Active
- 2012-09-21 PH PH1/2014/500657A patent/PH12014500657A1/en unknown
- 2012-09-21 MX MX2014003325A patent/MX350928B/es active IP Right Grant
- 2012-09-21 MY MYPI2014000851A patent/MY169574A/en unknown
- 2012-09-21 TR TR2019/01846T patent/TR201901846T4/tr unknown
- 2012-09-21 SI SI201231487T patent/SI2758071T1/sl unknown
- 2012-09-21 DK DK12772616.4T patent/DK2758071T3/en active
- 2012-09-21 PL PL12772616T patent/PL2758071T3/pl unknown
- 2012-09-21 AU AU2012312126A patent/AU2012312126B2/en active Active
- 2012-09-21 SG SG11201400795UA patent/SG11201400795UA/en unknown
-
2014
- 2014-03-18 IL IL231564A patent/IL231564A0/en active IP Right Grant
- 2014-03-20 ZA ZA2014/02071A patent/ZA201402071B/en unknown
-
2023
- 2023-12-22 US US18/395,150 patent/US20240270829A1/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007068411A2 (en) * | 2005-12-12 | 2007-06-21 | Ac Immune S.A. | Therapeutic vaccine |
| WO2010106127A2 (en) * | 2009-03-18 | 2010-09-23 | Ac Immune S.A. | Method for therapeutic use |
Non-Patent Citations (2)
| Title |
|---|
| ROIZEN NANCY J: "Complementary and alternative therapies for Down syndrome.", MENTAL RETARDATION AND DEVELOPMENTAL DISABILITIES RESEARCHREVIEWS, WILEY-LISS, NEW YORK, NY, US, vol. 11, no. 2, 1 April 2005 (2005-04-01), US, pages 149 - 155, XP002689521, ISSN: 1080-4013, DOI: 10.1002/mrdd.20063� * |
| STOLTZNER S E, ET AL.: "TEMPORAL ACCRUAL OF COMPLEMENT PROTEINS IN AMYLOID PLAQUES IN DOWN'S SYNDROME WITH ALZHEIMER'S DISEASE", AMERICAN JOURNAL OF PATHOLOGY., ELSEVIER INC., US, vol. 156, no. 02, 1 February 2000 (2000-02-01), US, pages 489 - 499, XP001146406, ISSN: 0002-9440 * |
Also Published As
| Publication number | Publication date |
|---|---|
| JP2014531455A (ja) | 2014-11-27 |
| KR20160005380A (ko) | 2016-01-15 |
| MX2014003325A (es) | 2014-05-21 |
| NZ622653A (en) | 2015-12-24 |
| HUE041277T2 (hu) | 2019-05-28 |
| KR20190035948A (ko) | 2019-04-03 |
| PT2758071T (pt) | 2019-01-11 |
| PL2758071T3 (pl) | 2019-08-30 |
| TR201901846T4 (tr) | 2019-03-21 |
| AU2012312126B2 (en) | 2016-11-10 |
| ES2712951T3 (es) | 2019-05-16 |
| AU2012312126A1 (en) | 2014-03-27 |
| EP2758071A1 (en) | 2014-07-30 |
| MX350928B (es) | 2017-09-26 |
| DK2758071T3 (en) | 2019-02-18 |
| WO2013044147A1 (en) | 2013-03-28 |
| IL231564A0 (en) | 2014-04-30 |
| CA2811188C (en) | 2020-04-28 |
| KR102129220B1 (ko) | 2020-07-02 |
| CN104039346A (zh) | 2014-09-10 |
| EA201400376A1 (ru) | 2014-09-30 |
| ZA201402071B (en) | 2017-08-30 |
| US20240270829A1 (en) | 2024-08-15 |
| CA2811188A1 (en) | 2013-03-23 |
| JP6110861B2 (ja) | 2017-04-05 |
| SI2758071T1 (sl) | 2019-01-31 |
| EP2758071B1 (en) | 2018-11-28 |
| KR20160099732A (ko) | 2016-08-22 |
| MY169574A (en) | 2019-04-22 |
| BR112014006871A2 (pt) | 2017-04-04 |
| SG11201400795UA (en) | 2014-10-30 |
| PH12014500657A1 (en) | 2014-05-05 |
| CN109847058A (zh) | 2019-06-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
Designated state(s): AM AZ KG TJ TM |