TR201901846T4 - Aşı terapisi. - Google Patents

Aşı terapisi. Download PDF

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Publication number
TR201901846T4
TR201901846T4 TR2019/01846T TR201901846T TR201901846T4 TR 201901846 T4 TR201901846 T4 TR 201901846T4 TR 2019/01846 T TR2019/01846 T TR 2019/01846T TR 201901846 T TR201901846 T TR 201901846T TR 201901846 T4 TR201901846 T4 TR 201901846T4
Authority
TR
Turkey
Prior art keywords
amyloid
vaccine therapy
young
syndrome
protein
Prior art date
Application number
TR2019/01846T
Other languages
English (en)
Inventor
Pfeifer Andrea
Muhs Andreas
Madani Rime
Vasilyevich Belichenko Pavel
Charles Mobley William
Original Assignee
Ac Immune Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ac Immune Sa filed Critical Ac Immune Sa
Publication of TR201901846T4 publication Critical patent/TR201901846T4/tr

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0007Nervous system antigens; Prions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10Peptides having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/385Haptens or antigens, bound to carriers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55555Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55572Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/60Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6018Lipids, e.g. in lipopeptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Mycology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Mevcut buluş, Down sendromlu (DS) genç ila orta yaşlı süjelerde amiloid ile alakalı patolojinin tedavi edilmesi, iyileştirilmesi ve engellenmesine yönelik vasıtalar sunar. Özellikle mevcut buluş, Down sendromlu genç ila orta yaşlı süjelerde amiloid ile alakalı patolojinin engelleyici tedavisinde kullanılmak üzere amiloid proteininden veya amiloid benzeri proteinden türetilmiş antijenik peptit fragmanlarını sunar.
TR2019/01846T 2011-09-23 2012-09-21 Aşı terapisi. TR201901846T4 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
USPCT/US2011/052992 2011-09-23

Publications (1)

Publication Number Publication Date
TR201901846T4 true TR201901846T4 (tr) 2019-03-21

Family

ID=47018510

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2019/01846T TR201901846T4 (tr) 2011-09-23 2012-09-21 Aşı terapisi.

Country Status (21)

Country Link
EP (1) EP2758071B1 (tr)
JP (1) JP6110861B2 (tr)
KR (3) KR20160099732A (tr)
CN (2) CN109847058A (tr)
AU (1) AU2012312126B2 (tr)
BR (1) BR112014006871A2 (tr)
CA (1) CA2811188C (tr)
DK (1) DK2758071T3 (tr)
EA (1) EA032494B1 (tr)
ES (1) ES2712951T3 (tr)
HU (1) HUE041277T2 (tr)
IL (1) IL231564A0 (tr)
MX (1) MX350928B (tr)
MY (1) MY169574A (tr)
PL (1) PL2758071T3 (tr)
PT (1) PT2758071T (tr)
SG (1) SG11201400795UA (tr)
SI (1) SI2758071T1 (tr)
TR (1) TR201901846T4 (tr)
WO (1) WO2013044147A1 (tr)
ZA (1) ZA201402071B (tr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2885010T3 (da) 2012-08-16 2020-02-03 Ipierian Inc Fremgangsmåder til behandling med tauopati
US8980270B2 (en) 2013-01-18 2015-03-17 Ipierian, Inc. Methods of treating a tauopathy
JP2017512751A (ja) 2014-02-14 2017-05-25 アイピエリアン,インコーポレイティド タウペプチド、抗タウ抗体、およびそれらの使用方法
US20220226447A1 (en) 2019-05-21 2022-07-21 Ac Immune Sa Anti-abeta vaccine therapy

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1018883A4 (en) 1997-08-28 2001-05-16 Ajay North America PLANT AND CROP PROTECTION METHODS AND COMPOSITIONS
EP1585520A1 (en) 2002-12-24 2005-10-19 Neurochem (International) Limited Therapeutic formulations for the treatment of beta-amyloid related diseases
AU2004209981B2 (en) * 2003-02-01 2009-02-26 Janssen Sciences Ireland Uc Active immunization to generate antibodies to soluble A-beta
US8663650B2 (en) 2003-02-21 2014-03-04 Ac Immune Sa Methods and compositions comprising supramolecular constructs
TWI379839B (en) * 2003-12-17 2012-12-21 Wyeth Llc Aβ immunogenic peptide carrier conjugates and methods of producing same
NZ552480A (en) * 2004-07-30 2010-01-29 Rinat Neuroscience Corp Antibodies directed against amyloid-beta peptide and methods of using same
MY181173A (en) * 2005-12-12 2020-12-21 Ac Immune Sa Therapeutic vaccine
TWI453217B (zh) * 2007-06-12 2014-09-21 Ac Immune Sa 抗β類澱粉蛋白單株抗體
SG174871A1 (en) * 2009-03-18 2011-11-28 Ac Immune Sa Method for therapeutic use

Also Published As

Publication number Publication date
ES2712951T3 (es) 2019-05-16
EP2758071A1 (en) 2014-07-30
PT2758071T (pt) 2019-01-11
HUE041277T2 (hu) 2019-05-28
WO2013044147A1 (en) 2013-03-28
SG11201400795UA (en) 2014-10-30
KR20160099732A (ko) 2016-08-22
IL231564A0 (en) 2014-04-30
KR102129220B1 (ko) 2020-07-02
EA201400376A1 (ru) 2014-09-30
MX2014003325A (es) 2014-05-21
PL2758071T3 (pl) 2019-08-30
CN104039346A (zh) 2014-09-10
KR20190035948A (ko) 2019-04-03
DK2758071T3 (en) 2019-02-18
CN109847058A (zh) 2019-06-07
BR112014006871A2 (pt) 2017-04-04
CA2811188C (en) 2020-04-28
JP2014531455A (ja) 2014-11-27
JP6110861B2 (ja) 2017-04-05
CA2811188A1 (en) 2013-03-23
AU2012312126B2 (en) 2016-11-10
AU2012312126A1 (en) 2014-03-27
KR20160005380A (ko) 2016-01-15
EA032494B1 (ru) 2019-06-28
MY169574A (en) 2019-04-22
NZ622653A (en) 2015-12-24
SI2758071T1 (sl) 2019-01-31
ZA201402071B (en) 2017-08-30
MX350928B (es) 2017-09-26
EP2758071B1 (en) 2018-11-28

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