AU2012312126B2 - Vaccine therapy - Google Patents

Vaccine therapy Download PDF

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Publication number
AU2012312126B2
AU2012312126B2 AU2012312126A AU2012312126A AU2012312126B2 AU 2012312126 B2 AU2012312126 B2 AU 2012312126B2 AU 2012312126 A AU2012312126 A AU 2012312126A AU 2012312126 A AU2012312126 A AU 2012312126A AU 2012312126 B2 AU2012312126 B2 AU 2012312126B2
Authority
AU
Australia
Prior art keywords
antigenic peptide
memory
peptide
syndrome
aci
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
AU2012312126A
Other languages
English (en)
Other versions
AU2012312126A1 (en
Inventor
Pavel Belichenko Vasilyevich
Rime MADANI
William Charles Mobley
Andreas Muhs
Andrea Pfeifer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AC Immune SA
Original Assignee
AC Immune SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AC Immune SA filed Critical AC Immune SA
Publication of AU2012312126A1 publication Critical patent/AU2012312126A1/en
Application granted granted Critical
Publication of AU2012312126B2 publication Critical patent/AU2012312126B2/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0007Nervous system antigens; Prions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10Peptides having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/385Haptens or antigens, bound to carriers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55555Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55572Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/60Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6018Lipids, e.g. in lipopeptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2012312126A 2011-09-23 2012-09-21 Vaccine therapy Active AU2012312126B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
USPCT/US2011/052992 2011-09-23
USPCT/US2011/052992 2011-09-23
PCT/US2012/056728 WO2013044147A1 (en) 2011-09-23 2012-09-21 Vaccine therapy

Publications (2)

Publication Number Publication Date
AU2012312126A1 AU2012312126A1 (en) 2014-03-27
AU2012312126B2 true AU2012312126B2 (en) 2016-11-10

Family

ID=47018510

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2012312126A Active AU2012312126B2 (en) 2011-09-23 2012-09-21 Vaccine therapy

Country Status (23)

Country Link
US (1) US20240270829A1 (enExample)
EP (1) EP2758071B1 (enExample)
JP (1) JP6110861B2 (enExample)
KR (3) KR102129220B1 (enExample)
CN (2) CN104039346A (enExample)
AU (1) AU2012312126B2 (enExample)
BR (1) BR112014006871A2 (enExample)
CA (1) CA2811188C (enExample)
DK (1) DK2758071T3 (enExample)
EA (1) EA032494B1 (enExample)
ES (1) ES2712951T3 (enExample)
HU (1) HUE041277T2 (enExample)
IL (1) IL231564A0 (enExample)
MX (1) MX350928B (enExample)
MY (1) MY169574A (enExample)
PH (1) PH12014500657A1 (enExample)
PL (1) PL2758071T3 (enExample)
PT (1) PT2758071T (enExample)
SG (1) SG11201400795UA (enExample)
SI (1) SI2758071T1 (enExample)
TR (1) TR201901846T4 (enExample)
WO (1) WO2013044147A1 (enExample)
ZA (1) ZA201402071B (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ630542A (en) 2012-08-16 2017-06-30 Ipierian Inc Methods of treating a tauopathy
US8980270B2 (en) 2013-01-18 2015-03-17 Ipierian, Inc. Methods of treating a tauopathy
JP2017512751A (ja) 2014-02-14 2017-05-25 アイピエリアン,インコーポレイティド タウペプチド、抗タウ抗体、およびそれらの使用方法
CA3118692A1 (en) 2018-11-06 2020-05-14 Alsatech, Inc. Cell-based gene therapy for neurodegenerative diseases
SG11202112329RA (en) * 2019-05-21 2021-12-30 Ac Immune Sa Anti-abeta vaccine therapy
KR20250137159A (ko) 2023-01-26 2025-09-17 에이씨 이뮨 에스에이 항-a베타 백신 요법

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007068411A2 (en) * 2005-12-12 2007-06-21 Ac Immune S.A. Therapeutic vaccine
WO2010106127A2 (en) * 2009-03-18 2010-09-23 Ac Immune S.A. Method for therapeutic use

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR9811401A (pt) 1997-08-28 2000-08-29 Ajay North America E Som Iodo Processos para proteger uma substância agrìcola contra pestes que são nocivas para a substância agrìcola e para a proteção de uma substãncia agrìcola, e, composição protetora para substâncias agrìcolas
AU2003292936A1 (en) 2002-12-24 2004-07-22 Neurochem (International) Limited Therapeutic formulations for the treatment of beta-amyloid related diseases
NZ567324A (en) * 2003-02-01 2009-08-28 Wyeth Corp Active immunization to generate antibodies to soluble A-beta
US8663650B2 (en) 2003-02-21 2014-03-04 Ac Immune Sa Methods and compositions comprising supramolecular constructs
JP4696079B2 (ja) * 2003-12-17 2011-06-08 ヤンセン アルツハイマー イミュノセラピー Aβ免疫原性ペプチド担体結合物およびそれの製造方法
MX2007000998A (es) * 2004-07-30 2007-07-11 Rinat Neuroscience Corp Anticuerpos dirigidos peptido beta-amiloide y procedimientos que usan los mismos.
NZ581835A (en) * 2007-06-12 2012-09-28 Ac Immune Sa Monoclonal anti beta amyloid antibody

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007068411A2 (en) * 2005-12-12 2007-06-21 Ac Immune S.A. Therapeutic vaccine
WO2010106127A2 (en) * 2009-03-18 2010-09-23 Ac Immune S.A. Method for therapeutic use

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
STOLTZNER et al., American Journal of Pathology, 2000, Vol. 156, No. 2, Pages 489-499. *

Also Published As

Publication number Publication date
JP2014531455A (ja) 2014-11-27
KR20160005380A (ko) 2016-01-15
MX2014003325A (es) 2014-05-21
NZ622653A (en) 2015-12-24
HUE041277T2 (hu) 2019-05-28
KR20190035948A (ko) 2019-04-03
PT2758071T (pt) 2019-01-11
PL2758071T3 (pl) 2019-08-30
TR201901846T4 (tr) 2019-03-21
ES2712951T3 (es) 2019-05-16
AU2012312126A1 (en) 2014-03-27
EP2758071A1 (en) 2014-07-30
MX350928B (es) 2017-09-26
DK2758071T3 (en) 2019-02-18
WO2013044147A1 (en) 2013-03-28
IL231564A0 (en) 2014-04-30
CA2811188C (en) 2020-04-28
KR102129220B1 (ko) 2020-07-02
CN104039346A (zh) 2014-09-10
EA201400376A1 (ru) 2014-09-30
ZA201402071B (en) 2017-08-30
US20240270829A1 (en) 2024-08-15
EA032494B1 (ru) 2019-06-28
CA2811188A1 (en) 2013-03-23
JP6110861B2 (ja) 2017-04-05
SI2758071T1 (sl) 2019-01-31
EP2758071B1 (en) 2018-11-28
KR20160099732A (ko) 2016-08-22
MY169574A (en) 2019-04-22
BR112014006871A2 (pt) 2017-04-04
SG11201400795UA (en) 2014-10-30
PH12014500657A1 (en) 2014-05-05
CN109847058A (zh) 2019-06-07

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