EA032372B1 - Комбинация гликозаминогликанов и циклодекстринов - Google Patents
Комбинация гликозаминогликанов и циклодекстринов Download PDFInfo
- Publication number
- EA032372B1 EA032372B1 EA201691246A EA201691246A EA032372B1 EA 032372 B1 EA032372 B1 EA 032372B1 EA 201691246 A EA201691246 A EA 201691246A EA 201691246 A EA201691246 A EA 201691246A EA 032372 B1 EA032372 B1 EA 032372B1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- cyclodextrin
- weight
- chondroitin sulfate
- combination
- hyaluronic acid
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
- A61K31/724—Cyclodextrins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/728—Hyaluronic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/737—Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/40—Cyclodextrins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Molecular Biology (AREA)
- Inorganic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Physical Education & Sports Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT002116A ITMI20132116A1 (it) | 2013-12-18 | 2013-12-18 | Associazione di glicosamminoglicani e ciclodestrine |
PCT/IB2014/002774 WO2015092516A1 (en) | 2013-12-18 | 2014-12-15 | Combination of glycosaminoglycans and cyclodextrins |
Publications (2)
Publication Number | Publication Date |
---|---|
EA201691246A1 EA201691246A1 (ru) | 2016-10-31 |
EA032372B1 true EA032372B1 (ru) | 2019-05-31 |
Family
ID=50115999
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA201691246A EA032372B1 (ru) | 2013-12-18 | 2014-12-15 | Комбинация гликозаминогликанов и циклодекстринов |
Country Status (13)
Country | Link |
---|---|
US (1) | US9974803B2 (zh) |
EP (1) | EP3082869B1 (zh) |
CN (1) | CN105899233B (zh) |
BR (1) | BR112016013834B1 (zh) |
CA (1) | CA2932987C (zh) |
EA (1) | EA032372B1 (zh) |
ES (1) | ES2707971T3 (zh) |
IT (1) | ITMI20132116A1 (zh) |
MA (1) | MA39077A1 (zh) |
PT (1) | PT3082869T (zh) |
TN (1) | TN2016000206A1 (zh) |
TR (1) | TR201819270T4 (zh) |
WO (1) | WO2015092516A1 (zh) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ITUB20153110A1 (it) * | 2015-08-13 | 2017-02-13 | Alfakjn S R L | Composizione liquida iniettabile per uso nella terapia infiltrativa intra-articolare |
IT201600075246A1 (it) | 2016-07-19 | 2018-01-19 | Jointherapeutics S R L | Composizioni comprendenti una matrice polisaccaridica per il rilascio controllato di principi attivi. |
IT201800010415A1 (it) * | 2018-11-19 | 2020-05-19 | Innate S R L | Composizione iniettabile comprendente acido ialuronico e trealosio e uso della detta composizione. |
US20230218657A1 (en) * | 2020-06-02 | 2023-07-13 | National University Of Singapore | Compositions, their uses in therapy and methods thereof |
Citations (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001066601A1 (en) * | 2000-03-10 | 2001-09-13 | Fidia Farmaceutici S.P.A. | Clathrate complexes formed by hyaluronic acid derivatives and use thereof as pharmaceuticals |
WO2003041724A1 (en) * | 2001-11-13 | 2003-05-22 | Alcon, Inc. | Use of a mixture of sodium hyaluronate and chondroitin sulfate for the treatment of osteoarthritis |
CN1451369A (zh) * | 2003-03-13 | 2003-10-29 | 吉林大学 | 环糊精衍生物在化妆品中的应用 |
US20080003257A1 (en) * | 2002-10-16 | 2008-01-03 | Marcum Frank D | Composition and Method for Treating Connective Tissue Damage |
CN101112381A (zh) * | 2006-07-24 | 2008-01-30 | 凌沛学 | 一种关节腔内注射用药物组合物 |
US20080193425A1 (en) * | 2002-10-07 | 2008-08-14 | Zymogenetics, Inc. | Methods for administering fgf18 |
EP1967186A1 (en) * | 2005-12-27 | 2008-09-10 | Lion Corporation | Composition for soft contact lens and adsorption suppressing method |
WO2010031876A1 (en) * | 2008-09-22 | 2010-03-25 | Universiteit Gent | Carboxyethylated cyclodextrin polysulfates useful as medicaments |
US20100098764A1 (en) * | 2007-11-30 | 2010-04-22 | Allergan, Inc. | Polysaccharide gel formulation having multi-stage bioactive agent delivery |
CH705713B1 (de) * | 2012-09-21 | 2013-05-15 | Labo Cosprophar Ag | Dermokosmetische Zusammensetzung zur topischen Anwendung. |
CN103301118A (zh) * | 2013-06-27 | 2013-09-18 | 海南卫康制药(潜山)有限公司 | 注射用精氨酸布洛芬组合物 |
WO2013144867A1 (en) * | 2012-03-30 | 2013-10-03 | Fidia Farmaceutici S.P.A. | Pharmaceutical formulations comprising chondroitin sulfate and hyaluronic acid derivatives |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2811572B1 (fr) | 2000-07-17 | 2003-04-18 | Adir | Utilisation de cyclodextrines polysulfatees pour le traitement de l'arthrose |
CN101259139A (zh) * | 2008-03-13 | 2008-09-10 | 北京阜康仁生物制药科技有限公司 | 一种用于消炎镇痛的药用组合物 |
-
2013
- 2013-12-18 IT IT002116A patent/ITMI20132116A1/it unknown
-
2014
- 2014-12-15 EP EP14830561.8A patent/EP3082869B1/en active Active
- 2014-12-15 CA CA2932987A patent/CA2932987C/en active Active
- 2014-12-15 EA EA201691246A patent/EA032372B1/ru unknown
- 2014-12-15 BR BR112016013834-1A patent/BR112016013834B1/pt active IP Right Grant
- 2014-12-15 WO PCT/IB2014/002774 patent/WO2015092516A1/en active Application Filing
- 2014-12-15 TN TN2016000206A patent/TN2016000206A1/en unknown
- 2014-12-15 US US15/105,595 patent/US9974803B2/en active Active
- 2014-12-15 MA MA39077A patent/MA39077A1/fr unknown
- 2014-12-15 PT PT14830561T patent/PT3082869T/pt unknown
- 2014-12-15 TR TR2018/19270T patent/TR201819270T4/tr unknown
- 2014-12-15 ES ES14830561T patent/ES2707971T3/es active Active
- 2014-12-15 CN CN201480069024.0A patent/CN105899233B/zh active Active
Patent Citations (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001066601A1 (en) * | 2000-03-10 | 2001-09-13 | Fidia Farmaceutici S.P.A. | Clathrate complexes formed by hyaluronic acid derivatives and use thereof as pharmaceuticals |
WO2003041724A1 (en) * | 2001-11-13 | 2003-05-22 | Alcon, Inc. | Use of a mixture of sodium hyaluronate and chondroitin sulfate for the treatment of osteoarthritis |
US20080193425A1 (en) * | 2002-10-07 | 2008-08-14 | Zymogenetics, Inc. | Methods for administering fgf18 |
US20080003257A1 (en) * | 2002-10-16 | 2008-01-03 | Marcum Frank D | Composition and Method for Treating Connective Tissue Damage |
CN1451369A (zh) * | 2003-03-13 | 2003-10-29 | 吉林大学 | 环糊精衍生物在化妆品中的应用 |
EP1967186A1 (en) * | 2005-12-27 | 2008-09-10 | Lion Corporation | Composition for soft contact lens and adsorption suppressing method |
CN101112381A (zh) * | 2006-07-24 | 2008-01-30 | 凌沛学 | 一种关节腔内注射用药物组合物 |
US20100098764A1 (en) * | 2007-11-30 | 2010-04-22 | Allergan, Inc. | Polysaccharide gel formulation having multi-stage bioactive agent delivery |
WO2010031876A1 (en) * | 2008-09-22 | 2010-03-25 | Universiteit Gent | Carboxyethylated cyclodextrin polysulfates useful as medicaments |
WO2013144867A1 (en) * | 2012-03-30 | 2013-10-03 | Fidia Farmaceutici S.P.A. | Pharmaceutical formulations comprising chondroitin sulfate and hyaluronic acid derivatives |
CH705713B1 (de) * | 2012-09-21 | 2013-05-15 | Labo Cosprophar Ag | Dermokosmetische Zusammensetzung zur topischen Anwendung. |
CN103301118A (zh) * | 2013-06-27 | 2013-09-18 | 海南卫康制药(潜山)有限公司 | 注射用精氨酸布洛芬组合物 |
Non-Patent Citations (5)
Title |
---|
AZQFAN: "Bionova skincare with nano technology on at 1 a.m.", INTERNET CITATION, 27 April 2008 (2008-04-27), pages 1-8, XP002537745, Retrieved from the Internet:URLrhttp://community.qvc.com/topic/Beauty-Banter/Bionova-Skincare-Nano/5700022656, [retrieved on 2009-07-17], the whole document * |
SINHA V R, NANDA A, KUMRIA R: "CYCLODEXTRINS AS SUSTAINED-RELEASE CARRIERS", PHARMACEUTICAL TECHNOLOGY, ADVANSTAR COMMUNICATIONS, EUGENE, OR, US, vol. 26, no. 10, 1 October 2002 (2002-10-01), US, pages 36 + 38 + 40 + 42 + 44 + 46, XP008013880, ISSN: 0147-8087 * |
WPI / Thomson Week 200417, 29 October 2003 Derwent World Patents Index; Class B04, XP002728093, LUO G; MOU Y; YAN G: "Use of cyclodextrin derivatives in cosmetics for eliminating wrinkles, delaying skin senility and preventing and treating pigmentation, chloasma, is an artificial analogue enzyme with the activity of glutathione peroxidase" * |
WPI / Thomson Week 200852, 30 January 2008 Derwent World Patents Index; Class B04, XP002728092, LING P; RONG X: "Drug composition used in articular cavity injection for treating arthritis contains sodium hyaluronate and chondroitin sulfate having predetermined molecular weight" * |
WPI / Thomson Week 201404, 18 September 2013 Derwent World Patents Index; Class B05, XP002728091, HAO J; LI B; WANG J; WANG L; WU H: "Arginine ibuprofen injection composition used for treating arthritis comprises arginine ibuprofen, melatonin and cyclodextrin, where melatonin contains quick release part and slow release part" * |
Also Published As
Publication number | Publication date |
---|---|
PT3082869T (pt) | 2019-02-06 |
BR112016013834A2 (zh) | 2017-08-08 |
MA39077A1 (fr) | 2017-11-30 |
BR112016013834B1 (pt) | 2022-11-22 |
EP3082869B1 (en) | 2018-10-31 |
EA201691246A1 (ru) | 2016-10-31 |
US20170035799A1 (en) | 2017-02-09 |
ITMI20132116A1 (it) | 2015-06-19 |
ES2707971T3 (es) | 2019-04-08 |
WO2015092516A1 (en) | 2015-06-25 |
CA2932987C (en) | 2021-10-12 |
TR201819270T4 (tr) | 2019-01-21 |
TN2016000206A1 (en) | 2017-10-06 |
CN105899233A (zh) | 2016-08-24 |
US9974803B2 (en) | 2018-05-22 |
CN105899233B (zh) | 2020-01-17 |
CA2932987A1 (en) | 2015-06-25 |
EP3082869A1 (en) | 2016-10-26 |
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