EA032129B1 - Пролекарство 1,1'-(1,6-диоксо-1,6-гександиил)бис-d-пролина - Google Patents
Пролекарство 1,1'-(1,6-диоксо-1,6-гександиил)бис-d-пролина Download PDFInfo
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- EA032129B1 EA032129B1 EA201692185A EA201692185A EA032129B1 EA 032129 B1 EA032129 B1 EA 032129B1 EA 201692185 A EA201692185 A EA 201692185A EA 201692185 A EA201692185 A EA 201692185A EA 032129 B1 EA032129 B1 EA 032129B1
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
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- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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- A—HUMAN NECESSITIES
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
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- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
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- A61P3/00—Drugs for disorders of the metabolism
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- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
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- A—HUMAN NECESSITIES
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Landscapes
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- Obesity (AREA)
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1407506.3A GB201407506D0 (en) | 2014-04-29 | 2014-04-29 | Novel compound |
| PCT/EP2015/058998 WO2015165833A1 (en) | 2014-04-29 | 2015-04-27 | A prodrug of 1,1'-(1,6-dioxo-1,6-hexanediyl)bis-d-proline |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EA201692185A1 EA201692185A1 (ru) | 2017-06-30 |
| EA032129B1 true EA032129B1 (ru) | 2019-04-30 |
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| Application Number | Title | Priority Date | Filing Date |
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| EA201692185A EA032129B1 (ru) | 2014-04-29 | 2015-04-27 | Пролекарство 1,1'-(1,6-диоксо-1,6-гександиил)бис-d-пролина |
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| IL (2) | IL248249A0 (enExample) |
| MA (1) | MA39406B1 (enExample) |
| MX (1) | MX2016014246A (enExample) |
| MY (1) | MY191088A (enExample) |
| PE (1) | PE20161558A1 (enExample) |
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| UA (1) | UA119871C2 (enExample) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9737505B2 (en) | 2014-04-29 | 2017-08-22 | Glaxosmithkline Intellectual Property Development Limited | Prodrug of 1,1′-(1,6-dioxo-1,6-hexanediyl)bis-D-proline |
| GB201518950D0 (en) * | 2015-10-27 | 2015-12-09 | Glaxosmithkline Ip Dev Ltd | Compound |
| GB202213162D0 (en) | 2022-09-08 | 2022-10-26 | Cambridge Entpr Ltd | Prodrugs |
Citations (1)
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| WO2003051836A1 (en) * | 2001-12-14 | 2003-06-26 | F. Hoffmann-La Roche Ag | Prodrugs to d-prolines |
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| ES2182203T3 (es) | 1997-10-31 | 2003-03-01 | Hoffmann La Roche | Derivados de d-prolina. |
| JP2006526612A (ja) | 2003-06-05 | 2006-11-24 | ファイザー・プロダクツ・インク | ベータ−ラクタマーゼ阻害剤・プロドラッグ |
| GB0313386D0 (en) | 2003-06-10 | 2003-07-16 | Univ London | Treatment of disease |
| KR20080004571A (ko) | 2005-04-12 | 2008-01-09 | 메이지 세이카 가부시키가이샤 | 2-티오에테닐 카바페넴 유도체 |
| GB0712503D0 (en) | 2007-06-27 | 2007-08-08 | Therapeutics Pentraxin Ltd | Use |
| UA108227C2 (xx) | 2010-03-03 | 2015-04-10 | Антигензв'язуючий білок | |
| US9737505B2 (en) | 2014-04-29 | 2017-08-22 | Glaxosmithkline Intellectual Property Development Limited | Prodrug of 1,1′-(1,6-dioxo-1,6-hexanediyl)bis-D-proline |
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- 2015-04-27 CA CA2947060A patent/CA2947060C/en active Active
- 2015-04-27 CR CR20160508A patent/CR20160508A/es unknown
- 2015-04-27 WO PCT/EP2015/058998 patent/WO2015165833A1/en not_active Ceased
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- 2015-04-27 BR BR112016025129A patent/BR112016025129A2/pt not_active Application Discontinuation
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- 2015-04-27 EP EP15720312.6A patent/EP3137457B1/en active Active
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2016
- 2016-10-09 IL IL248249A patent/IL248249A0/en active IP Right Grant
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2017
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2020
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003051836A1 (en) * | 2001-12-14 | 2003-06-26 | F. Hoffmann-La Roche Ag | Prodrugs to d-prolines |
Non-Patent Citations (1)
| Title |
|---|
| AESOP CHO: "Recent Advances in Oral Prodrug Discovery", ANNUAL REPORTS IN MEDICINAL CHEMISTRY, ACADEMIC PRESS, US, vol. 41, 1 January 2006 (2006-01-01), US, pages 395 - 407, XP009184520, ISSN: 0065-7743 * |
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