EA027972B1 - Новая кристаллическая форма - Google Patents
Новая кристаллическая форма Download PDFInfo
- Publication number
- EA027972B1 EA027972B1 EA201490536A EA201490536A EA027972B1 EA 027972 B1 EA027972 B1 EA 027972B1 EA 201490536 A EA201490536 A EA 201490536A EA 201490536 A EA201490536 A EA 201490536A EA 027972 B1 EA027972 B1 EA 027972B1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- rilapladib
- crystalline
- raman spectrum
- spectrum
- raman
- Prior art date
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- NNBGCSGCRSCFEA-UHFFFAOYSA-N 2-[2-[(2,3-difluorophenyl)methylsulfanyl]-4-oxoquinolin-1-yl]-n-[1-(2-methoxyethyl)piperidin-4-yl]-n-[[4-[4-(trifluoromethyl)phenyl]phenyl]methyl]acetamide Chemical compound C1CN(CCOC)CCC1N(C(=O)CN1C2=CC=CC=C2C(=O)C=C1SCC=1C(=C(F)C=CC=1)F)CC1=CC=C(C=2C=CC(=CC=2)C(F)(F)F)C=C1 NNBGCSGCRSCFEA-UHFFFAOYSA-N 0.000 claims description 250
- 229950004360 rilapladib Drugs 0.000 claims description 197
- 238000001237 Raman spectrum Methods 0.000 claims description 86
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- C—CHEMISTRY; METALLURGY
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
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- Pyridine Compounds (AREA)
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| Application Number | Priority Date | Filing Date | Title |
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| US201161530104P | 2011-09-01 | 2011-09-01 | |
| PCT/EP2012/067027 WO2013030374A1 (en) | 2011-09-01 | 2012-08-31 | Novel crystal form |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EA201490536A1 EA201490536A1 (ru) | 2014-08-29 |
| EA027972B1 true EA027972B1 (ru) | 2017-09-29 |
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| EA201490536A EA027972B1 (ru) | 2011-09-01 | 2012-08-31 | Новая кристаллическая форма |
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| SM (1) | SMT201800455T1 (https=) |
| UA (1) | UA114607C2 (https=) |
| WO (1) | WO2013030374A1 (https=) |
| ZA (1) | ZA201401176B (https=) |
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| SI2751094T1 (sl) * | 2011-09-01 | 2018-10-30 | Glaxo Group Limited | Nova kristalinična oblika |
| EP2764866A1 (en) | 2013-02-07 | 2014-08-13 | IP Gesellschaft für Management mbH | Inhibitors of nedd8-activating enzyme |
| US12583835B2 (en) * | 2020-03-30 | 2026-03-24 | Jiangsu Yahong Meditech Co., Ltd. | Crystal form of nitroxoline prodrug, pharmaceutical composition containing same, and preparation method therefor and application thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002030904A1 (en) * | 2000-10-10 | 2002-04-18 | Smithkline Beecham P.L.C. | Pyridinone derivatives for treatment of atherosclerosis |
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| US5503723A (en) | 1995-02-08 | 1996-04-02 | Eastman Kodak Company | Isolation of ultra small particles |
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| ES2847883T3 (es) | 2010-12-17 | 2021-08-04 | Glaxo Group Ltd | Uso de inhibidores de LP-PLA2 en el tratamiento y prevención de enfermedades oculares |
| SI2751094T1 (sl) * | 2011-09-01 | 2018-10-30 | Glaxo Group Limited | Nova kristalinična oblika |
| EP2764866A1 (en) | 2013-02-07 | 2014-08-13 | IP Gesellschaft für Management mbH | Inhibitors of nedd8-activating enzyme |
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002030904A1 (en) * | 2000-10-10 | 2002-04-18 | Smithkline Beecham P.L.C. | Pyridinone derivatives for treatment of atherosclerosis |
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