EA023774B1 - Cleansing composition - Google Patents

Abstract

The present invention relates to an antibacterial cleansing composition comprising an antibacterial component which comprises from 40 to 90 wt.% of pyruvic acid, from 5 to 55 wt.% of gentisic acid and from 5 to 55 wt.% of salicylic acid. The proposed composition can be used for cleaning a hard surface, for cleaning a toilet or handdishwashing.

Description

The present invention relates to an antibacterial cleansing composition.

Despite the prior art, there remains a need for more advanced antibacterial cleansing compositions. In particular, in compositions that can clean hard surfaces.

Accordingly, the present invention relates to an antibacterial cleansing composition containing an antibacterial component that contains from 40 to 90 wt.% Pyruvic acid; from 5 to 55 wt.% gentisic acid; and from 5 to 55 wt.% salicylic acid.

The inventors have shown that such compositions have a high activity with respect to both Epilogossossiidae and §1arjuosossi8 aigeik.

Preferably, the antibacterial component comprises from 0.001 to 5% by weight of the composition.

Preferably, the composition comprises a cleansing surfactant.

Preferably, the composition is a hard surface cleaning composition.

Preferably, the composition is a toilet block composition.

Preferably, the composition is a toilet cleansing composition.

Preferably, the cleaning composition used in accordance with the present invention further comprises a detergent surfactant in a concentration of from 0 to 50 wt.%. The specified surfactant (active detergent) is usually selected from anionic and nonionic active detergents. The cleaning composition may further comprise cationic, amphoteric, and zwitterionic surfactants.

Preferably, the total surfactant content of said cleansing composition is at least 0.1%, more preferably at least 0.5%. The maximum content is usually less than 30 wt.%, Preferably not more than 20 wt.%, Or even it is equal to or less than 10 wt.%.

Suitable synthetic anionic surfactants (not soaps) are water-soluble salts of organic monoesters of sulfuric acid and sulfonic acids, which have a branched or straight chain alkyl group containing from 6 to 22 carbon atoms in the alkyl moiety in the molecular structure.

Examples of such anionic surfactants are water-soluble salts: sulphates of (primary) alcohols with a long chain (for example, 6-22 carbon atoms), which are hereinafter referred to as ATP, especially sulphates obtained by sulphation of fatty alcohols formed by the reduction of glycerides of tall or coconut oil;

alkylbenzenesulfonates, for example those in which the alkyl group contains from 6 to 20 carbon atoms;

secondary alkanesulfonates; and mixtures thereof.

Also suitable are alkyl glyceryl ether sulfate salts, especially fatty alcohol ethers recovered from tall oil or coconut oil;

fatty acid monoglyceride sulfates;

sulfates of ethoxylated aliphatic alcohols containing 1-12 ethylene oxide groups; sulfates of alkyl phenol ethylene oxide ethers having from 1 to 8 ethylene oxide units per molecule, in which the alkyl groups contain from 4 to 14 carbon atoms;

the reaction product of fatty acids esterified with isothionic acid and neutralized with alkali, and mixtures thereof.

Preferred water-soluble synthetic anionic surfactants are salts of alkali metal alkylbenzenesulfonates (such as sodium and potassium) and alkaline earth metals (such as calcium and magnesium) and mixtures with olefin sulfonates and alkyl sulfates and fatty acid monoglycerides sulfates.

The most preferred anionic surfactants are alkyl aromatic sulfonates, such as alkyl benzene sulfonates containing from 6 to 20 carbon atoms in a straight or branched chain alkyl group, specific examples of which are sodium salts of alkyl benzenesulfonates, alkyltoluenesulfonates, sulfonesulfonates, sulfonesulfonates, ammonium and sodium dinonylnaphthalene sulfonate.

If a synthetic anionic surfactant is to be used, the amount present in the cleansing compositions of the invention will typically be at least 0.1%, preferably at least 0.5%, more preferably at least 1.0% but not more than 20%, preferably not more than 15%, more preferably not more than 10%.

A suitable class of nonionic surfactants can be broadly described as compounds obtained by condensation of simple alkylene oxides that are hydrophilic in nature, with an aliphatic or alkyl aromatic hydrophobic compound having a reactive hydrogen atom. The length of this hydrophilic or polyoxyalkylene chain attached to

- 1,023,774 to any particular hydrophobic group, can be easily adjusted to obtain a compound having the desired balance between the hydrophilic and hydrophobic elements. This allows the selection of nonionic surfactants with a suitable hydrophilic-lipophilic balance (HLB) value. Specific examples include condensation products of aliphatic alcohols having 8 to 22 carbon atoms in a straight or branched chain configuration with ethylene oxide, such as coconut alcohol / ethylene oxide condensates having 2 to 15 moles of ethylene oxide per 1 mole of coconut alcohol;

alkyl phenol condensates having C6-C15 alkyl groups with 5-25 moles of ethylene oxide per 1 mole of alkyl phenol;

condensates of the reaction product of ethylene diamine and propylene oxide with ethylene oxide, and these condensates contain from 40 to 80% ethylene oxide groups by weight and have a molecular weight of from 5000 to 11000.

Other classes of nonionic surfactants are tertiary amine oxides of the structure Κ ¹ Κ ² Κ ³ Ν-Θ, where K ¹ represents an alkyl group with 8-20 carbon atoms, and each of K ² and K ³ is an alkyl or hydroxyalkyl group with 1 -3 carbon atoms, for example dimethyldodecylamine oxide;

tertiary phosphine oxides of the structure K'K ² K ³ PO, where K ¹ represents an alkyl group with 8-20 carbon atoms, and each of K ² and K ³ is an alkyl or hydroxyalkyl group with 1-3 carbon atoms, for example dimethyldodecylphosphine oxide;

dialkyl sulfoxides of the structure K'K ² 8 = O, where K ¹ represents an alkyl group of 10-18 carbon atoms, and K ² is methyl or ethyl, for example methyl tetradecyl sulfoxide;

fatty acid alkylolamides such as ethanolamides; condensates of alkylene oxides with fatty acid alkylolamides; alkyl mercaptans.

The concentration of a non-ionic surfactant other than APO that can be used in said cleaning composition of the invention will preferably be at least 0.1%, more preferably at least 0.5%, most preferably at least 1% . A suitable amount is not more than 20%, preferably not more than 15% and most preferably not more than 10%.

You can also optionally include amphoteric, cationogenic or zwitterionic surfactants in these compositions.

Suitable amphoteric surfactants are derivatives of aliphatic secondary and tertiary amines containing an alkyl group of 8 to 20 carbon atoms, and an aliphatic group substituted by an anionic group solubilizing in water, for example sodium 3-dodecylamino-propionate, sodium 3-dodecylaminopropanesulfonate and ^ 2-hydroxydodecyl- ^ methyl taurate sodium.

Examples of suitable cationic surfactants can be found among quaternary ammonium salts containing one or two alkyl or aralkyl groups having from 8 to 20 carbon atoms and two or three small aliphatic (e.g. methyl) groups, for example cetyltrimethylammonium chloride.

A specific group of surfactants are tertiary amines obtained by condensation of ethylene and / or propylene oxide with long chain aliphatic amines. These compounds behave as nonionic surfactants in an alkaline environment and as cationic surfactants in an acidic environment.

Examples of suitable zwitterionic surfactants can be found among derivatives of aliphatic quaternary ammonium, sulfonium and phosphonium compounds having aliphatic groups of 8 to 18 carbon atoms and aliphatic groups substituted by an anionic group solubilizing in water, for example betaine and betaine derivatives, such such as alkyl betaine, in particular C12-C16 alkyl betaine, 3-Щ ^ -dimethyl- ^ hexadecylammonium) -propane-1-betaine sulfonate,

- (dodecylmethylsulfonium) propane-1-betaine sulfonate, 3 - (cetylmethylphosphonium) propane-1-betaine sulfonate and H ^ dimethyl ^ -dedecylglycine. Other well-known betaines are alkyl amidopropyl betaines, for example those in which the alkyl amide group is derived from coconut oil fatty acids.

Further examples of suitable surfactants are compounds commonly used as surfactants given in widely known manuals: 8shTass Asyus Adspy Uo1. 1, 8c11 \ var1 / & RSGGU. BiSksksssss 1949; 8gGass AsDus AdShK Uo1.2, BsyuagSh, Rspu & Vsgsb, 1n1sg5S1spss 1958; the new edition of MsSiYuysop'k YeshiSShsgk and OsYugdsyk, published by MapiGasShgtd SoiGssyopssgk Sotrapu; Tskkhbs-Taksbspis, N.Shasys, 2pb Ebp., Sag1 Naiksg Usg1ad, 1981.

In a preferred embodiment, the composition in accordance with the invention has a pH of from 2 to 13, more preferably at least 3 and not more than 12. The cleaning methods of the invention for cleaning kitchen hard surfaces can preferably be carried out

- 2 023774 at pH values in the alkaline range. Preferably, the method of the invention is carried out at a pH of from about 6 to 12, more preferably from 7 to 10.

The pH of the cleaning composition used in the method of the invention can be adjusted with organic or inorganic acids or bases. Preferred inorganic bases are preferably alkali or alkaline earth metal hydroxides, ammonia, carbonates or bicarbonates, the alkali metal being preferably sodium or potassium, or the alkaline earth metal is preferably calcium or magnesium. The organic bases are preferably amines, alkanolamines and other suitable amino compounds. Inorganic acids may include hydrochloric acid, sulfuric acid, or phosphoric acid, and organic acids may include acetic acid, citric acid, or formic acid, as well as mixtures of dicarboxylic acids, such as CaStlx (trademark Καάίοί Otoir) and 8okalai ES8 (trademark BAR) .

The cleaning composition used in accordance with the present invention may contain abrasive materials. In a preferred embodiment, the composition used in accordance with the present invention does not contain abrasive material. The composition may contain other ingredients that contribute to their cleansing effect. For example, they may contain additives to enhance the detergent action and mixtures of additives in an amount up to 25%, in particular when the composition contains one or more anionic surfactants.

Such an additive, if any, will preferably comprise at least 0.1% of the composition. Suitable inorganic and organic additives are well known in the art.

An additional optional ingredient in the compositions used in accordance with the invention is a soap control foam material that can be used in compositions that tend to form excessive foam when used. Examples thereof are fatty acids or their salts (soaps), isoparaffins, silicone oils, and combinations thereof.

Soaps are salts of fatty acids and include alkali metal soaps such as sodium, potassium and ammonium salts of fatty acids containing from about 8 to 24 carbon atoms, and preferably from about 10 to about 20 carbon atoms. Particularly effective are sodium and potassium and mono-, di- and triethanolamine salts of fatty acid mixtures made from palm oil, coconut oil and peanut oil. The amount of fatty acid or soap, if used, may be at least 0.005%, preferably from 0.1 to 2% by weight of the composition.

If the hydrocarbon solvent is present in a sufficiently high concentration, this alone may provide part or all of the necessary anti-foaming activity.

The compositions may also contain, in addition to the ingredients already mentioned, various other optional ingredients, such as colorants, brighteners, optical brighteners, suspending agents, washing enzymes, compatible bleaching agents (especially peroxide compounds and active chlorine releasing compounds), solvents , cosolvents, gelling agents, additional freeze-thaw stabilizers, bactericides, preservatives (e.g. 1,2-benzisothiazolin-3-one), hydrotropes and perfumes.

In a preferred embodiment, the composition of the present invention does not contain tannic acid or related compounds such as gallic acid and / or propyl gallate. It was found that when tannic acid enters the alkaline liquid cleansing composition, it forms aesthetically unpleasant yellow-brown solutions, and this can lead to brown cement at the joints between the tiles.

In another preferred embodiment, the composition of the present invention does not contain malonic acid. An antioxidant like malonic acid is needed in relatively high concentrations to achieve the benefits of post-treatment. In addition, consumers can consider residues of malonic acid on solid surfaces, such as the kitchen and bathroom, as harmful and undesirable.

In another preferred embodiment, the composition of the present invention does not contain formic acid. Formic acid has a pungent odor, and residues on hard surfaces are aesthetically undesirable.

The composition of the invention can be stored and sprayed using any suitable means, but nebulizers are particularly preferred. Pump-type spray guns (whether with an aerosol or non-aerosol blower) and dispensers for application (bottles, etc.) can also be used. Thus, in a preferred embodiment of the second aspect of the invention, it is proposed to use an aqueous cleaning composition in accordance with the invention, wherein said composition is contained in a container, and the container further comprises an aerosol dispenser for spraying the composition as an aerosol. Preferably, the aerosol dispenser is a trigger atomizer, but may be any mechanical means for expelling the liquid in the form of a spray or aerosol.

- 3 023774

Example 1

To determine antibacterial efficacy, each test mixture was tested against two bacteria commonly found on home hard surfaces. They were Eyetosossik Igaye and §1арЬу1ossossik aigeyik.

Test mixtures were tested to find a value in the concentration range at which 50% death was achieved. This value determines the degree of activity A.

In this study, activity is determined so that 1 corresponds to the lowest possible concentration and 0 corresponds to the highest concentration.

Accordingly, the less activity, the better the prepared mixture.

To determine the synergy mathematically in a mixture of η-compounds calculate the total fractional activity (TPA) as follows.

For each compound ί in the mixture (ί-1,2, ... η), the fractional activity of RA _{1 is} calculated

For compound ί, it is defined as

- HX '4' where A _t1X is the activity of the test mixture under study and A ₁ is the activity of compound ί taken separately.

Then the total fractional activity (TPA) of the mixture is calculated as follows:

And tra = ’/ = 1 where λν is the mass based on the concentration used and”

Σ ^ ^{= 1} ι = 1

So if

TPA = 1, then the mixture has additive activity;

TPA> 1, then the mixture has antagonistic activity;

TPA <1, then the mixture has synergistic activity; and TPA level <0.90 is considered a strong synergy.

This is based on the fractional inhibitory concentration used in biocidal treatment. For reference see:

Vegebayit MS (1978), and MeSzob Gog 1kpepde kupegdu \\ ύ1ι apo pit eG adeyk. PPGesOooik I1keakek 137 (2), 122-130;

Bleuyu MS (2000), Mercurial Soputioptebbe oG sottyupk oG apybas1eg1a1 adakek adaty sapodes ogdatktk. TIETKTsu 565, 565-570;

Na11, M.1. e! A1 (1983), Thé GgOoOlTiLe, I have a little social media (P1C) sbekh a teakige oG kupegdu, TAiTyuGo1 SietoShegaru 11, 427-433.

Example 2

Bathroom Cleaner:

from 0.1 to 10% of a surfactant selected from nonionic, anionic, cationogenic or amphoteric surfactants;

mixtures mentioned above can be used in any ratio (limited only by phase behavior);

cationic surfactants may be specifically included if a hygiene component is required;

from 0.1 to 5% organic acid.

Optional ingredients solvents (0.1-5%); polymers (0.01-2%); hydrotropes; buffer;

perfume;

dye;

preservative;

usually pH less than 4 (alkaline options available on the market, simultaneously containing a complexing agent).

Specific examples:

3.5% nonionic ethoxylate alcohol No. 6O1 91-8.8EO;

4% citric acid;

1% dipropylene glycol n-butyl ether;

0.2% xanthan gum polymer;

+ auxiliary components (perfume, dye, etc.); pH 3.8;

- 4 023774

5% nonionic ethoxylate alcohol Νοοάοΐ 91-8, 8EO;

4% citric acid;

0.5% polyacrylic acid;

+ auxiliary components (perfume, dye, etc.); pH 4.

Kitchen Cleaner: Universal:

from 0.1 to 10% of a surfactant selected from nonionic, anionic, cationogenic and amphoteric surfactants;

mixtures mentioned above can be used in any ratio (limited only by phase behavior);

cationic surfactants may be specifically included for hygiene purposes;

0-5% chelating agent.

Optional ingredients: solvents (0.1-5%); polymers (0.01-2%); hydrotropes;

buffer; perfume; dye; preservative; usually pH> 10.

Specific examples:

5% nonionic ethoxylate alcohol Νβοάοΐ 91-5, 5ЕО;

4% monoethanolamine;

1% dipropylene glycol n-butyl ether;

0.15% crosslinked acrylic polymer ίτιΛοροΙ ΕΌΤ2623;

+ auxiliary components (perfume, dye, etc.); pH 11.2;

3% nonionic ethoxylate alcohol Νβοάοΐ 91-5, 5ЕО;

2% lauryl ether sulfate 8LE8, 1ΕΟ;

4% monoethanolamine;

1% dipropylene glycol n-butyl ether; pH 11.

Example 3

General Purpose Cleaner (OPC - Floor Cleaner): universal:

ODPs usually contain reduced amounts of components compared to specialized cleaners for the kitchen and bathroom:

from 0.1 to 10% of a surfactant selected from nonionic, anionic, cationogenic and amphoteric surfactants;

mixtures mentioned above can be used in any ratio (limited only by phase behavior);

cationic surfactants may be specifically included for hygiene purposes;

0-5% chelating agent.

Optional ingredients: solvents (0.1-5%); polymers (0.01-2%); hydrotropes;

buffer; perfume; dye; preservative; any pH.

General Purpose Cleaner (OPC - Floor Cleaner): Special:

3% nonionic ethoxylate alcohol Νβοάοΐ 91-5, 5ЕО;

1.5% cationic surfactant benzalkyl ammonium chloride;

1.5% sodium tripolyphosphate 8TP 0.3% Να ₂ ί'.Ό ₃ ;

+ auxiliary components (perfume, dye, etc.); pH ~ 11;

3% lauryl ether sulphate 8LE8, 1ΕΟ;

1% citric acid;

- 5 023774 + auxiliary components (perfume, dye, etc.); pH4.

Example 4

Cleansing composition for the toilet.

Toilet cleaners are typically acidic in nature and have high viscosity and pseudo-plasticity properties created by a core micellar structure:

from 0.1 to 10% of a surfactant selected from nonionic, anionic, cationogenic and amphoteric surfactants;

mixtures mentioned above can be used in any ratio (limited only by phase behavior);

cationic surfactants may be specifically included for hygiene purposes;

0-5% bleach;

0-10% acid;

0-5% chelating agent.

Optional ingredients:

solvents (0.1-5%);

polymers (0.01-2%);

hydrotropes;

buffer;

perfume;

dye;

preservative;

pH is usually <4.

A specific example of a toilet cleaner:

3% ethoxylated amine surfactant ESHSSSP BTB12;

4% sulfamic acid;

0.5% sodium cumene sulfonate (hydrotrop);

4% hydrogen peroxide;

+ auxiliary components (perfume, dye, etc.); pH ~ 1.

Example 5

Composition for washing dishes manually.

Dishwashing liquid for washing with hands (ΗΌ \ ν): universal:

from 0.1 to 40% of a surfactant selected from nonionic, anionic, cationogenic or amphoteric surfactants;

mixtures mentioned above can be used in any ratio (limited only by phase behavior);

cationic surfactants may be specifically included for hygiene purposes.

Optional ingredients: solvents (0.1-5%); polymers (0.01-2%); hydrotropes; buffer;

perfume;

dye;

preservative;

any pH, but usually ~ 4-10.

ΗΌν: special:

20% lauryl ether sulfate δΕΕδ, 1ЕО;

8% linear sodium alkylbenzenesulfonate ΝαΕΛδ;

5% cocoamidopropyl betaine CAPB;

1% nonionic ethoxylate alcohol No. OB1 91-8, 8EO;

2.5% \ 1ΰδ (Ε;

+ auxiliary components (perfume, dye, etc.); pH ~ 7;

11% linear sodium alkylbenzenesulfonate ΝαΕΛδ;

3.5% lauryl ether sulfate δΕΕδ, 1EO;

1% \ 1ΰδ (Ε;

+ auxiliary components (perfume, dye, etc.); pH ~ 7.

Claims (6)

CLAIM 1. Antibacterial cleansing composition containing an antibacterial component, which contains from 40 to 90 wt.% Pyruvic acid; from 5 to 55 wt.% gentisic acid and from 5 to 55 wt.% salicylic acid. 2. The composition according to claim 1, in which the antibacterial component is from 0.001 to 5 wt.% Composition. 3. Composition according to any one of the preceding paragraphs, containing a cleansing surfactant. 4. Composition according to any one of the preceding claims, which is a cleansing composition for a hard surface. 5. Composition according to any one of the preceding paragraphs, which is a cleansing composition for the toilet. 6. Composition according to any one of the preceding paragraphs, which is a composition for manual dishwashing.