EA021874B1 - Фармацевтическая композиция антимикробного действия для парентерального введения и способ ее получения - Google Patents
Фармацевтическая композиция антимикробного действия для парентерального введения и способ ее получения Download PDFInfo
- Publication number
- EA021874B1 EA021874B1 EA201001449A EA201001449A EA021874B1 EA 021874 B1 EA021874 B1 EA 021874B1 EA 201001449 A EA201001449 A EA 201001449A EA 201001449 A EA201001449 A EA 201001449A EA 021874 B1 EA021874 B1 EA 021874B1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- silicon dioxide
- beta
- weight
- pharmaceutical composition
- preparing
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title claims abstract description 7
- 230000000845 anti-microbial effect Effects 0.000 title claims abstract description 6
- 238000004519 manufacturing process Methods 0.000 title abstract description 4
- 238000007911 parenteral administration Methods 0.000 title abstract 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims abstract description 24
- 239000000377 silicon dioxide Substances 0.000 claims abstract description 12
- 235000012239 silicon dioxide Nutrition 0.000 claims abstract description 10
- 239000003782 beta lactam antibiotic agent Substances 0.000 claims abstract description 9
- 239000002132 β-lactam antibiotic Substances 0.000 claims abstract description 9
- 229940124586 β-lactam antibiotics Drugs 0.000 claims abstract description 9
- 239000000203 mixture Substances 0.000 claims abstract description 8
- 239000002245 particle Substances 0.000 claims abstract description 5
- 239000000126 substance Substances 0.000 claims abstract description 5
- 238000005299 abrasion Methods 0.000 claims abstract description 3
- 238000002347 injection Methods 0.000 claims abstract description 3
- 239000007924 injection Substances 0.000 claims abstract description 3
- 230000001225 therapeutic effect Effects 0.000 claims abstract description 3
- 238000000034 method Methods 0.000 claims description 2
- 239000000843 powder Substances 0.000 claims 3
- 239000002086 nanomaterial Substances 0.000 claims 1
- 239000003814 drug Substances 0.000 abstract description 4
- 238000002360 preparation method Methods 0.000 abstract description 4
- 230000003115 biocidal effect Effects 0.000 abstract description 3
- 208000035473 Communicable disease Diseases 0.000 abstract description 2
- 206010061218 Inflammation Diseases 0.000 abstract description 2
- 239000004480 active ingredient Substances 0.000 abstract description 2
- 239000002131 composite material Substances 0.000 abstract description 2
- 230000002458 infectious effect Effects 0.000 abstract description 2
- 208000027866 inflammatory disease Diseases 0.000 abstract description 2
- 230000004054 inflammatory process Effects 0.000 abstract description 2
- 244000005700 microbiome Species 0.000 abstract description 2
- 210000001539 phagocyte Anatomy 0.000 abstract description 2
- 239000000243 solution Substances 0.000 abstract description 2
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 229940088710 antibiotic agent Drugs 0.000 abstract 1
- 239000004599 antimicrobial Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
- A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Inorganic Chemistry (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Dermatology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Priority Applications (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EA201001449A EA021874B1 (ru) | 2010-09-13 | 2010-09-13 | Фармацевтическая композиция антимикробного действия для парентерального введения и способ ее получения |
| CN2011800044095A CN103096896A (zh) | 2010-09-13 | 2011-05-11 | 供不经肠投药的抗菌用药物组合物及其制造方法 |
| CA2785228A CA2785228A1 (en) | 2010-09-13 | 2011-05-11 | Pharmaceutical composition with antimicrobial activity for parenteral administration and process for preparing same |
| JP2013528146A JP2013537190A (ja) | 2010-09-13 | 2011-05-11 | 非経口投与のための抗菌作用を有する医薬組成物及びその製造方法 |
| MX2012010535A MX2012010535A (es) | 2010-09-13 | 2011-05-11 | Composicion farmaceutica con actividad antimicrobiana para administracion parenteral y procedimiento de produccion de la misma. |
| NZ598831A NZ598831A (en) | 2010-09-13 | 2011-05-11 | Pharmaceutical composition with antimicrobial activity for parenteral administration and process for preparing same |
| BR112012023964A BR112012023964A2 (pt) | 2010-09-13 | 2011-05-11 | composição farmacêutica de ação antimicrobiana para administração parenteral e processo de produção da mesma |
| AU2011302724A AU2011302724C1 (en) | 2010-09-13 | 2011-05-11 | Pharmaceutical composition with antimicrobial activity for parenteral administration and process for preparing same |
| PCT/RU2011/000320 WO2012036585A1 (ru) | 2010-09-13 | 2011-05-11 | Фармацевтическая композиция антимикробного действия для парентерального введения и способ её получения |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EA201001449A EA021874B1 (ru) | 2010-09-13 | 2010-09-13 | Фармацевтическая композиция антимикробного действия для парентерального введения и способ ее получения |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EA201001449A1 EA201001449A1 (ru) | 2012-02-28 |
| EA021874B1 true EA021874B1 (ru) | 2015-09-30 |
Family
ID=45908207
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA201001449A EA021874B1 (ru) | 2010-09-13 | 2010-09-13 | Фармацевтическая композиция антимикробного действия для парентерального введения и способ ее получения |
Country Status (9)
| Country | Link |
|---|---|
| JP (1) | JP2013537190A (pt) |
| CN (1) | CN103096896A (pt) |
| AU (1) | AU2011302724C1 (pt) |
| BR (1) | BR112012023964A2 (pt) |
| CA (1) | CA2785228A1 (pt) |
| EA (1) | EA021874B1 (pt) |
| MX (1) | MX2012010535A (pt) |
| NZ (1) | NZ598831A (pt) |
| WO (1) | WO2012036585A1 (pt) |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUP9901877A1 (hu) * | 1996-02-29 | 1999-12-28 | Fujisawa Pharmaceutical Co., Ltd. | Béta-laktám antibiotikumot tartalmazó tabletták és eljárás előállításukra |
| WO2008062429A2 (en) * | 2006-08-11 | 2008-05-29 | Panacea Biotec Limited | Particles for delivery of active ingredients, process of making and compositions thereof |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2377985C2 (ru) | 2006-12-25 | 2010-01-10 | Сергей Михайлович Юдин | Средство для лечения инфекционных болезней, вызванных множественно-устойчивыми бактериями |
-
2010
- 2010-09-13 EA EA201001449A patent/EA021874B1/ru not_active IP Right Cessation
-
2011
- 2011-05-11 MX MX2012010535A patent/MX2012010535A/es not_active Application Discontinuation
- 2011-05-11 JP JP2013528146A patent/JP2013537190A/ja not_active Withdrawn
- 2011-05-11 CA CA2785228A patent/CA2785228A1/en not_active Abandoned
- 2011-05-11 AU AU2011302724A patent/AU2011302724C1/en not_active Ceased
- 2011-05-11 BR BR112012023964A patent/BR112012023964A2/pt not_active IP Right Cessation
- 2011-05-11 CN CN2011800044095A patent/CN103096896A/zh active Pending
- 2011-05-11 NZ NZ598831A patent/NZ598831A/xx not_active IP Right Cessation
- 2011-05-11 WO PCT/RU2011/000320 patent/WO2012036585A1/ru active Application Filing
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUP9901877A1 (hu) * | 1996-02-29 | 1999-12-28 | Fujisawa Pharmaceutical Co., Ltd. | Béta-laktám antibiotikumot tartalmazó tabletták és eljárás előállításukra |
| WO2008062429A2 (en) * | 2006-08-11 | 2008-05-29 | Panacea Biotec Limited | Particles for delivery of active ingredients, process of making and compositions thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2012036585A1 (ru) | 2012-03-22 |
| CN103096896A (zh) | 2013-05-08 |
| MX2012010535A (es) | 2012-11-16 |
| CA2785228A1 (en) | 2012-03-22 |
| WO2012036585A8 (ru) | 2012-10-04 |
| AU2011302724C1 (en) | 2012-11-29 |
| EA201001449A1 (ru) | 2012-02-28 |
| AU2011302724B2 (en) | 2012-06-28 |
| BR112012023964A2 (pt) | 2016-08-02 |
| AU2011302724A1 (en) | 2012-05-03 |
| NZ598831A (en) | 2013-11-29 |
| JP2013537190A (ja) | 2013-09-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
Designated state(s): AM AZ BY KZ KG MD TJ TM RU |