EA014183B1 - Пленочная аппликационная система для трансмукозного введения стероидного гормона - Google Patents

Пленочная аппликационная система для трансмукозного введения стероидного гормона Download PDF

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Publication number
EA014183B1
EA014183B1 EA200702102A EA200702102A EA014183B1 EA 014183 B1 EA014183 B1 EA 014183B1 EA 200702102 A EA200702102 A EA 200702102A EA 200702102 A EA200702102 A EA 200702102A EA 014183 B1 EA014183 B1 EA 014183B1
Authority
EA
Eurasian Patent Office
Prior art keywords
steroid hormone
application system
film
μεντ
cellulose
Prior art date
Application number
EA200702102A
Other languages
English (en)
Russian (ru)
Other versions
EA200702102A1 (ru
Inventor
Маркус Крумме
Альберт Радльмайер
Саша Генераль
Михаель Диттген
Кэйт Ензен
Original Assignee
Лтс Ломан Тэрапи-Зистеме Аг
Байер Шеринг Фарма Акциенгезельшафт
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36998911&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA014183(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Лтс Ломан Тэрапи-Зистеме Аг, Байер Шеринг Фарма Акциенгезельшафт filed Critical Лтс Ломан Тэрапи-Зистеме Аг
Publication of EA200702102A1 publication Critical patent/EA200702102A1/ru
Publication of EA014183B1 publication Critical patent/EA014183B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/26—Androgens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/34—Gestagens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A61P5/40—Mineralocorticosteroids, e.g. aldosterone; Drugs increasing or potentiating the activity of mineralocorticosteroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A61P5/44—Glucocorticosteroids; Drugs increasing or potentiating the activity of glucocorticosteroids

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EA200702102A 2005-03-31 2006-03-15 Пленочная аппликационная система для трансмукозного введения стероидного гормона EA014183B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102005015128A DE102005015128B4 (de) 2005-03-31 2005-03-31 Wafer enthaltend Steroidhormone
PCT/EP2006/002358 WO2006102990A2 (de) 2005-03-31 2006-03-15 Wafer enthaltend steroidhormone

Publications (2)

Publication Number Publication Date
EA200702102A1 EA200702102A1 (ru) 2008-04-28
EA014183B1 true EA014183B1 (ru) 2010-10-29

Family

ID=36998911

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200702102A EA014183B1 (ru) 2005-03-31 2006-03-15 Пленочная аппликационная система для трансмукозного введения стероидного гормона

Country Status (26)

Country Link
US (2) US9763960B2 (enExample)
EP (1) EP1863444B1 (enExample)
JP (2) JP5843416B2 (enExample)
KR (2) KR20140063740A (enExample)
CN (2) CN104983669B (enExample)
AR (1) AR054245A1 (enExample)
AU (1) AU2006228820B2 (enExample)
BR (1) BRPI0609601A2 (enExample)
CA (1) CA2598892C (enExample)
CR (1) CR9468A (enExample)
DE (1) DE102005015128B4 (enExample)
DO (1) DOP2006000070A (enExample)
EA (1) EA014183B1 (enExample)
GT (1) GT200600126A (enExample)
IL (1) IL186081A0 (enExample)
MX (1) MX2007012081A (enExample)
NO (1) NO20075404L (enExample)
NZ (1) NZ592882A (enExample)
PE (1) PE20061194A1 (enExample)
SG (1) SG179459A1 (enExample)
SV (1) SV2008002466A (enExample)
TW (1) TWI393576B (enExample)
UA (1) UA92011C2 (enExample)
UY (1) UY29441A1 (enExample)
WO (1) WO2006102990A2 (enExample)
ZA (1) ZA200706116B (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8492369B2 (en) 2010-04-12 2013-07-23 Clarus Therapeutics Inc Oral testosterone ester formulations and methods of treating testosterone deficiency comprising same
US8241664B2 (en) 2005-04-15 2012-08-14 Clarus Therapeutics, Inc Pharmaceutical delivery systems for hydrophobic drugs and compositions comprising same
DE102006027796A1 (de) * 2006-06-16 2007-12-20 Lts Lohmann Therapie-Systeme Ag Estrogen-Gestagen-Kombinationen
NZ586666A (en) * 2008-02-13 2012-04-27 Bayer Schering Pharma Ag Estradiol-containing drug delivery system
KR20100117603A (ko) * 2008-02-13 2010-11-03 바이엘 쉐링 파마 악티엔게젤샤프트 안정화 효과를 갖는 약물 전달 시스템
TW201008569A (en) * 2008-08-08 2010-03-01 Bayer Schering Pharma Ag Progestin-containing drug delivery system
CA2744127A1 (en) * 2008-11-21 2010-05-27 Bayer Schering Pharma Aktiengesellschaft Drug delivery system
US12186426B2 (en) 2009-10-30 2025-01-07 Ix Biopharma Ltd. Solid dosage form
EP2493457B1 (en) 2009-10-30 2017-08-09 IX Biopharma Ltd Fast dissolving solid dosage form
US10806703B2 (en) * 2012-01-20 2020-10-20 Lts Lohmann Therapie-System Ag Transmucosal administration system for a pharmaceutical drug
AU2012385956B2 (en) 2012-07-23 2017-03-30 Crayola, Llc Dissolvable films and methods of using the same
DE102017112527B4 (de) * 2017-06-07 2019-01-03 Lts Lohmann Therapie-Systeme Ag Schnell zerfallende Schaumwafer mit hohem Flächengewicht
MX2020008147A (es) * 2018-02-02 2020-10-28 Acerus Biopharma Inc Metodos de terapia de testosterona.

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19847252A1 (de) * 1998-10-02 2000-04-13 Jenapharm Gmbh Verwendung von Testosteronestern und/oder Testosteron zur Herstellung von bukkal applizierbaren bioadhäsiven Systemen mit zeitgesteuerter Arzneistoffwirkung
WO2000042992A2 (en) * 1999-01-21 2000-07-27 Lavipharm Laboratories, Inc. Compositions and methods for mucosal delivery
WO2003015748A2 (en) * 2001-08-16 2003-02-27 Access Pharmaceuticals, Inc. Mucoadhesive erodible drug delivery device for controlled administration of pharmaceuticals and other active compounds
US20030096012A1 (en) * 2001-11-21 2003-05-22 Jerome Besse Film-forming powder, compositions containing it, methods for their preparation and their uses

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB981372A (en) * 1960-05-04 1965-01-27 Pfizer Ltd Pharmaceutical formulations for oral administration to animals
US4136162A (en) 1974-07-05 1979-01-23 Schering Aktiengesellschaft Medicament carriers in the form of film having active substance incorporated therein
US4764378A (en) * 1986-02-10 1988-08-16 Zetachron, Inc. Buccal drug dosage form
DE69312487T2 (de) * 1992-05-18 1997-11-27 Minnesota Mining & Mfg Einrichtung zur transmucosalen wirkstoffabgabe
DE19646392A1 (de) * 1996-11-11 1998-05-14 Lohmann Therapie Syst Lts Zubereitung zur Anwendung in der Mundhöhle mit einer an der Schleimhaut haftklebenden, Pharmazeutika oder Kosmetika zur dosierten Abgabe enthaltenden Schicht
US6264981B1 (en) * 1999-10-27 2001-07-24 Anesta Corporation Oral transmucosal drug dosage using solid solution
US20030092658A1 (en) * 2001-02-02 2003-05-15 Meyers Rachel E. Novel human enzyme family members and uses thereof
AU2001273231A1 (en) * 2000-07-06 2002-01-21 Delsys Pharmaceutical Corporation Method for formulating healthcare products with enhanced stability
GB0100760D0 (en) * 2001-01-11 2001-02-21 Biocompatibles Ltd Drug delivery from stents
JO2492B1 (en) * 2003-04-28 2009-10-05 شيرينج ايه جي A pharmaceutical formula in the form of aqueous gel for the skin use of its active ingredients
JP2007500729A (ja) * 2003-07-31 2007-01-18 アイバックス コーポレイション 雄性及び雌性の性機能障害の治療方法
PL1670433T3 (pl) * 2003-10-10 2013-03-29 Ferring Bv Przezskórna formulacja farmaceutyczna do zmniejszania pozostałości na skórze

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19847252A1 (de) * 1998-10-02 2000-04-13 Jenapharm Gmbh Verwendung von Testosteronestern und/oder Testosteron zur Herstellung von bukkal applizierbaren bioadhäsiven Systemen mit zeitgesteuerter Arzneistoffwirkung
WO2000042992A2 (en) * 1999-01-21 2000-07-27 Lavipharm Laboratories, Inc. Compositions and methods for mucosal delivery
WO2003015748A2 (en) * 2001-08-16 2003-02-27 Access Pharmaceuticals, Inc. Mucoadhesive erodible drug delivery device for controlled administration of pharmaceuticals and other active compounds
US20030096012A1 (en) * 2001-11-21 2003-05-22 Jerome Besse Film-forming powder, compositions containing it, methods for their preparation and their uses

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
JAY S. ET AL.: "TRANSMUCOSAL DELIVERY OF TESTOSTERONE IN RABBITS USING NOVEL BI-LAYER MUCOADHESIVE WAX-FILM COMPOSITE DISKS", JOURNAL OF PHARMACEUTICAL SCIENCES, AMERICAN PHARMACEUTICAL ASSOCIATION. WASHINGTON, US, vol. 91, no. 9, September 2002 (2002-09), pages 2016-2025, KHR001125855, ISSN: 0022-3549, abstract, Seite 2017, rechte Spalte - Seite 2018, linke Spalte, Absatz "Preparation of WFCs containing Testosterone", table 1, Seite 2024, linke Spalte, Absatz "Conclusions" *

Also Published As

Publication number Publication date
JP2013155190A (ja) 2013-08-15
EA200702102A1 (ru) 2008-04-28
WO2006102990A2 (de) 2006-10-05
JP5843416B2 (ja) 2016-01-13
TW200714299A (en) 2007-04-16
US9763960B2 (en) 2017-09-19
AU2006228820B2 (en) 2011-08-25
SV2008002466A (es) 2008-02-08
ZA200706116B (en) 2008-11-26
KR20140063740A (ko) 2014-05-27
EP1863444A2 (de) 2007-12-12
JP2008534533A (ja) 2008-08-28
US20060222708A1 (en) 2006-10-05
CN104983669A (zh) 2015-10-21
BRPI0609601A2 (pt) 2010-04-20
NZ592882A (en) 2012-12-21
KR20080002798A (ko) 2008-01-04
SG179459A1 (en) 2012-04-27
TWI393576B (zh) 2013-04-21
CN101132766A (zh) 2008-02-27
DE102005015128B4 (de) 2008-12-11
CN104983669B (zh) 2018-05-18
EP1863444B1 (de) 2015-12-09
PE20061194A1 (es) 2006-11-23
US20170348321A1 (en) 2017-12-07
GT200600126A (es) 2007-03-14
DE102005015128A1 (de) 2006-10-05
NO20075404L (no) 2007-12-20
AU2006228820A1 (en) 2006-10-05
MX2007012081A (es) 2007-11-21
WO2006102990A3 (de) 2007-03-22
IL186081A0 (en) 2008-01-20
KR101428625B1 (ko) 2014-08-13
UA92011C2 (ru) 2010-09-27
DOP2006000070A (es) 2007-08-15
AR054245A1 (es) 2007-06-13
CR9468A (es) 2008-01-21
CA2598892C (en) 2014-10-14
UY29441A1 (es) 2006-10-31
CA2598892A1 (en) 2006-10-05

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Designated state(s): AM AZ KZ KG MD TJ TM

TC4A Change in name of a patent proprietor in a eurasian patent
PC4A Registration of transfer of a eurasian patent by assignment
PC4A Registration of transfer of a eurasian patent by assignment
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): BY RU