EA009289B1 - ЛЕЧЕНИЕ ХРОНИЧЕСКОЙ ВОСПАЛИТЕЛЬНОЙ ДЕМИЕЛИНИЗИРУЮЩЕЙ ПОЛИНЕВРОПАТИИ С ИСПОЛЬЗОВАНИЕМ β-ИНТЕРФЕРОНА - Google Patents
ЛЕЧЕНИЕ ХРОНИЧЕСКОЙ ВОСПАЛИТЕЛЬНОЙ ДЕМИЕЛИНИЗИРУЮЩЕЙ ПОЛИНЕВРОПАТИИ С ИСПОЛЬЗОВАНИЕМ β-ИНТЕРФЕРОНА Download PDFInfo
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- EA009289B1 EA009289B1 EA200500545A EA200500545A EA009289B1 EA 009289 B1 EA009289 B1 EA 009289B1 EA 200500545 A EA200500545 A EA 200500545A EA 200500545 A EA200500545 A EA 200500545A EA 009289 B1 EA009289 B1 EA 009289B1
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- 239000004334 sorbic acid Substances 0.000 description 1
- 235000010199 sorbic acid Nutrition 0.000 description 1
- 229940075582 sorbic acid Drugs 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- 125000006850 spacer group Chemical group 0.000 description 1
- 230000002269 spontaneous effect Effects 0.000 description 1
- 230000006641 stabilisation Effects 0.000 description 1
- 238000011105 stabilization Methods 0.000 description 1
- 230000000087 stabilizing effect Effects 0.000 description 1
- 238000010561 standard procedure Methods 0.000 description 1
- 239000008223 sterile water Substances 0.000 description 1
- 125000001424 substituent group Chemical group 0.000 description 1
- 239000008362 succinate buffer Substances 0.000 description 1
- 230000019635 sulfation Effects 0.000 description 1
- 238000005670 sulfation reaction Methods 0.000 description 1
- 238000006277 sulfonation reaction Methods 0.000 description 1
- 230000001629 suppression Effects 0.000 description 1
- 239000003765 sweetening agent Substances 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 230000002194 synthesizing effect Effects 0.000 description 1
- 238000007910 systemic administration Methods 0.000 description 1
- 239000007916 tablet composition Substances 0.000 description 1
- 229940095064 tartrate Drugs 0.000 description 1
- 229940090016 tegretol Drugs 0.000 description 1
- 210000002435 tendon Anatomy 0.000 description 1
- 150000007970 thio esters Chemical class 0.000 description 1
- RSPCKAHMRANGJZ-UHFFFAOYSA-N thiohydroxylamine Chemical compound SN RSPCKAHMRANGJZ-UHFFFAOYSA-N 0.000 description 1
- 210000003371 toe Anatomy 0.000 description 1
- RUELTTOHQODFPA-UHFFFAOYSA-N toluene 2,6-diisocyanate Chemical compound CC1=C(N=C=O)C=CC=C1N=C=O RUELTTOHQODFPA-UHFFFAOYSA-N 0.000 description 1
- 238000007070 tosylation reaction Methods 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 230000001131 transforming effect Effects 0.000 description 1
- 239000003029 tricyclic antidepressant agent Substances 0.000 description 1
- 229950002929 trinitrophenol Drugs 0.000 description 1
- HRXKRNGNAMMEHJ-UHFFFAOYSA-K trisodium citrate Chemical compound [Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O HRXKRNGNAMMEHJ-UHFFFAOYSA-K 0.000 description 1
- 229940038773 trisodium citrate Drugs 0.000 description 1
- 239000002691 unilamellar liposome Substances 0.000 description 1
- 238000011144 upstream manufacturing Methods 0.000 description 1
- 235000013311 vegetables Nutrition 0.000 description 1
- 230000002747 voluntary effect Effects 0.000 description 1
- 229920003169 water-soluble polymer Polymers 0.000 description 1
- 239000001993 wax Substances 0.000 description 1
- 230000003313 weakening effect Effects 0.000 description 1
- 230000003442 weekly effect Effects 0.000 description 1
- 239000000080 wetting agent Substances 0.000 description 1
- 235000021119 whey protein Nutrition 0.000 description 1
- 150000003751 zinc Chemical class 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
- A61K38/215—IFN-beta
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Transplantation (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Psychology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41430702P | 2002-09-27 | 2002-09-27 | |
| PCT/US2003/030532 WO2004028472A2 (en) | 2002-09-27 | 2003-09-26 | THERAPIES FOR CHRONIC INFLAMMATORY DEMYELINATING POLYNEUROPATHY USING INTERFERON-β |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| EA200500545A2 EA200500545A2 (ru) | 2005-08-25 |
| EA200500545A3 EA200500545A3 (ru) | 2007-04-27 |
| EA009289B1 true EA009289B1 (ru) | 2007-12-28 |
Family
ID=32043377
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA200500545A EA009289B1 (ru) | 2002-09-27 | 2003-09-26 | ЛЕЧЕНИЕ ХРОНИЧЕСКОЙ ВОСПАЛИТЕЛЬНОЙ ДЕМИЕЛИНИЗИРУЮЩЕЙ ПОЛИНЕВРОПАТИИ С ИСПОЛЬЗОВАНИЕМ β-ИНТЕРФЕРОНА |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US20060182715A1 (enExample) |
| EP (1) | EP1575531B9 (enExample) |
| JP (3) | JP2006513990A (enExample) |
| KR (1) | KR20050059195A (enExample) |
| CN (2) | CN102038938A (enExample) |
| AT (1) | ATE520412T1 (enExample) |
| AU (1) | AU2003277006C1 (enExample) |
| BR (1) | BR0314548A (enExample) |
| CA (1) | CA2500189A1 (enExample) |
| DK (1) | DK1575531T3 (enExample) |
| EA (1) | EA009289B1 (enExample) |
| GE (1) | GEP20094699B (enExample) |
| IS (1) | IS7746A (enExample) |
| MX (1) | MXPA05003243A (enExample) |
| NO (1) | NO20052059L (enExample) |
| NZ (1) | NZ565990A (enExample) |
| PL (1) | PL377612A1 (enExample) |
| RS (1) | RS20050255A (enExample) |
| UA (1) | UA86749C2 (enExample) |
| WO (1) | WO2004028472A2 (enExample) |
| ZA (1) | ZA200502416B (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2636456C2 (ru) * | 2011-10-01 | 2017-11-23 | Глитек, Инк. | Гликозилированный полипептид и содержащая его фармацевтическая композиция |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1575531T3 (da) * | 2002-09-27 | 2011-11-21 | Biogen Idec Inc | Terapier for kronisk inflammatorisk demyeliniserende polyneuropati under anvendelse af interferon-beta |
| TW200633718A (en) * | 2004-12-16 | 2006-10-01 | Applied Research Systems | Treatment of hepatitis c in the asian population |
| EP2572734B1 (en) * | 2006-10-31 | 2016-04-06 | East Carolina University | Cytokine-based fusion proteins for treatment of immune disorders |
| EP3348275A3 (en) | 2009-03-31 | 2018-10-24 | East Carolina University | Cytokines and neuroantigens for treatment of immune disorders |
| GB201212878D0 (en) | 2012-07-20 | 2012-09-05 | Pike Justin | Authentication method and system |
| EP3072513A1 (en) | 2015-03-26 | 2016-09-28 | Medday | Biotin for treating Amyotrophic lateral sclerosis |
| GB201520760D0 (en) | 2015-05-27 | 2016-01-06 | Mypinpad Ltd And Licentia Group Ltd | Encoding methods and systems |
| WO2020009437A1 (ko) * | 2018-07-04 | 2020-01-09 | 서울대학교산학협력단 | 신경손상의 면역세포치료 |
| GB201916441D0 (en) | 2019-11-12 | 2019-12-25 | Mypinpad Ltd | Computer-implemented system and method |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2166959C2 (ru) * | 1994-04-12 | 2001-05-20 | Рисерч Дивелопмент Фаундейшн | Способ лечения аутоиммунных заболеваний с использованием интерферонов типа i |
| US6419934B1 (en) * | 1999-02-24 | 2002-07-16 | Edward L. Tobinick | TNF modulators for treating neurological disorders associated with viral infection |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0154316B1 (en) * | 1984-03-06 | 1989-09-13 | Takeda Chemical Industries, Ltd. | Chemically modified lymphokine and production thereof |
| ZA878295B (en) * | 1986-11-06 | 1988-05-03 | Amarillo Cell Culture Co. Inc. | Treatment of immuno-resistant disease |
| DE3712564A1 (de) * | 1987-04-14 | 1988-11-24 | Bioferon Biochem Substanz | Verfahren zur konstruktion einer animalen zellinie fuer die herstellung von humanem interferon-beta |
| DE4128319A1 (de) * | 1991-08-27 | 1993-03-04 | Bioferon Biochem Substanz | Neues rekombinantes human-ifn-beta, verfahren zu dessen herstellung und dieses enthaltende pharmazeutische zubereitungen |
| US5545723A (en) * | 1994-03-15 | 1996-08-13 | Biogen Inc. | Muteins of IFN-β |
| IL113280A (en) * | 1994-04-12 | 2004-12-15 | Res Dev Foundation | A preparation for the treatment of self-immunization diseases with the help of interferon of one type |
| TW403653B (en) * | 1995-12-25 | 2000-09-01 | Otsuka Pharma Co Ltd | Dry compositions |
| ES2265693T3 (es) * | 1998-10-16 | 2007-02-16 | Biogen Idec Ma Inc. | Proteinas de fusion con interferon-beta y usos. |
| AU762616B2 (en) * | 1998-10-16 | 2003-07-03 | Biogen Ma Inc. | Polymer conjugates of interferon beta-1a and uses |
| JP2002537769A (ja) * | 1999-02-26 | 2002-11-12 | ヒューマン ジノーム サイエンシーズ， インコーポレイテッド | ヒトエンドカインαおよび使用方法 |
| US6531122B1 (en) * | 1999-08-27 | 2003-03-11 | Maxygen Aps | Interferon-β variants and conjugates |
| EP1334128A2 (en) * | 2000-11-02 | 2003-08-13 | Maxygen Aps | New multimeric interferon beta polypeptides |
| JP2004534523A (ja) * | 2001-02-27 | 2004-11-18 | マキシゲン・エイピーエス | 新規なインターフェロンβ様分子 |
| WO2002072019A2 (en) * | 2001-03-13 | 2002-09-19 | Vical Incorporated | Interferon-beta polynucleotide therapy for autoimmune and inflammatory diseases |
| DK1575531T3 (da) * | 2002-09-27 | 2011-11-21 | Biogen Idec Inc | Terapier for kronisk inflammatorisk demyeliniserende polyneuropati under anvendelse af interferon-beta |
-
2003
- 2003-09-26 DK DK03798770.8T patent/DK1575531T3/da active
- 2003-09-26 CN CN201010256064XA patent/CN102038938A/zh active Pending
- 2003-09-26 RS YUP-2005/0255A patent/RS20050255A/sr unknown
- 2003-09-26 CA CA002500189A patent/CA2500189A1/en not_active Abandoned
- 2003-09-26 JP JP2004540030A patent/JP2006513990A/ja active Pending
- 2003-09-26 AU AU2003277006A patent/AU2003277006C1/en not_active Ceased
- 2003-09-26 US US10/529,522 patent/US20060182715A1/en not_active Abandoned
- 2003-09-26 AT AT03798770T patent/ATE520412T1/de not_active IP Right Cessation
- 2003-09-26 BR BR0314548-4A patent/BR0314548A/pt not_active IP Right Cessation
- 2003-09-26 MX MXPA05003243A patent/MXPA05003243A/es not_active Application Discontinuation
- 2003-09-26 GE GEAP20038765A patent/GEP20094699B/en unknown
- 2003-09-26 CN CNA038253720A patent/CN1802170A/zh active Pending
- 2003-09-26 UA UAA200503909A patent/UA86749C2/ru unknown
- 2003-09-26 EA EA200500545A patent/EA009289B1/ru not_active IP Right Cessation
- 2003-09-26 KR KR1020057005145A patent/KR20050059195A/ko not_active Ceased
- 2003-09-26 EP EP03798770A patent/EP1575531B9/en not_active Expired - Lifetime
- 2003-09-26 WO PCT/US2003/030532 patent/WO2004028472A2/en not_active Ceased
- 2003-09-26 NZ NZ565990A patent/NZ565990A/en not_active IP Right Cessation
- 2003-09-26 PL PL377612A patent/PL377612A1/pl unknown
-
2005
- 2005-03-15 IS IS7746A patent/IS7746A/is unknown
- 2005-03-23 ZA ZA200502416A patent/ZA200502416B/en unknown
- 2005-04-27 NO NO20052059A patent/NO20052059L/no not_active Application Discontinuation
-
2006
- 2006-09-14 JP JP2006250090A patent/JP2007039463A/ja active Pending
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2010
- 2010-11-11 US US12/944,396 patent/US20120058083A1/en not_active Abandoned
-
2011
- 2011-02-04 JP JP2011023226A patent/JP2011132248A/ja not_active Withdrawn
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2166959C2 (ru) * | 1994-04-12 | 2001-05-20 | Рисерч Дивелопмент Фаундейшн | Способ лечения аутоиммунных заболеваний с использованием интерферонов типа i |
| US6419934B1 (en) * | 1999-02-24 | 2002-07-16 | Edward L. Tobinick | TNF modulators for treating neurological disorders associated with viral infection |
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| Title |
|---|
| SAIDA K., Treatment of neuro-immunologic diseases by immunosuppres-sants, 1994, nov.52(11): 3046-52, referat, [Naydeno 12.12.2005], Medline [on-layn] PMID: 7996708 referat ÔÇ£Entsiklopediya lekarstv, registr lekarstvennykh sredstv RossiiÔÇØ, Moskva, 2001, str. 142, 364-365 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2636456C2 (ru) * | 2011-10-01 | 2017-11-23 | Глитек, Инк. | Гликозилированный полипептид и содержащая его фармацевтическая композиция |
Also Published As
| Publication number | Publication date |
|---|---|
| BR0314548A (pt) | 2005-08-09 |
| EP1575531A4 (en) | 2008-01-23 |
| GEP20094699B (en) | 2009-06-10 |
| ATE520412T1 (de) | 2011-09-15 |
| NO20052059D0 (no) | 2005-04-27 |
| CA2500189A1 (en) | 2004-04-08 |
| IS7746A (is) | 2005-03-15 |
| MXPA05003243A (es) | 2005-09-12 |
| WO2004028472A3 (en) | 2006-01-19 |
| KR20050059195A (ko) | 2005-06-17 |
| PL377612A1 (pl) | 2006-02-06 |
| EP1575531A2 (en) | 2005-09-21 |
| RS20050255A (sr) | 2007-08-03 |
| JP2007039463A (ja) | 2007-02-15 |
| JP2006513990A (ja) | 2006-04-27 |
| CN102038938A (zh) | 2011-05-04 |
| US20120058083A1 (en) | 2012-03-08 |
| AU2003277006A1 (en) | 2004-04-19 |
| AU2003277006C1 (en) | 2010-04-01 |
| UA86749C2 (en) | 2009-05-25 |
| JP2011132248A (ja) | 2011-07-07 |
| WO2004028472A2 (en) | 2004-04-08 |
| CN1802170A (zh) | 2006-07-12 |
| US20060182715A1 (en) | 2006-08-17 |
| DK1575531T3 (da) | 2011-11-21 |
| EP1575531B1 (en) | 2011-08-17 |
| AU2003277006B2 (en) | 2009-09-10 |
| EA200500545A3 (ru) | 2007-04-27 |
| NO20052059L (no) | 2005-06-27 |
| NZ565990A (en) | 2009-10-30 |
| EP1575531B9 (en) | 2012-02-22 |
| EA200500545A2 (ru) | 2005-08-25 |
| ZA200502416B (en) | 2005-10-20 |
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| MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
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