EA008972B1 - Новые кристаллические формы гидробромида клопидогреля и способы их получения - Google Patents

Новые кристаллические формы гидробромида клопидогреля и способы их получения Download PDF

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Publication number
EA008972B1
EA008972B1 EA200601311A EA200601311A EA008972B1 EA 008972 B1 EA008972 B1 EA 008972B1 EA 200601311 A EA200601311 A EA 200601311A EA 200601311 A EA200601311 A EA 200601311A EA 008972 B1 EA008972 B1 EA 008972B1
Authority
EA
Eurasian Patent Office
Prior art keywords
clopidogrel
hydrobromide
solution
crystalline form
clopidogrel hydrobromide
Prior art date
Application number
EA200601311A
Other languages
English (en)
Russian (ru)
Other versions
EA200601311A1 (ru
Inventor
Йосеф Гайичек
Павел Пигера
Гана Степанкова
Original Assignee
Зентива А.С.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CZ200461A external-priority patent/CZ295244B6/cs
Priority claimed from CZ20041192A external-priority patent/CZ20041192A3/cs
Application filed by Зентива А.С. filed Critical Зентива А.С.
Publication of EA200601311A1 publication Critical patent/EA200601311A1/ru
Publication of EA008972B1 publication Critical patent/EA008972B1/ru

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
EA200601311A 2004-01-13 2004-12-21 Новые кристаллические формы гидробромида клопидогреля и способы их получения EA008972B1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CZ200461A CZ295244B6 (cs) 2004-01-13 2004-01-13 Klopidogrel hydrobromid v krystalické formě I a způsob jeho přípravy
CZ20041192A CZ20041192A3 (cs) 2004-12-07 2004-12-07 Zpusob výroby krystalického klopidogrelu hydrobromidu
PCT/CZ2004/000089 WO2005068471A1 (fr) 2004-01-13 2004-12-21 Nouvelles formes cristallines d'hydrobromure de clopidogrel et leurs procedes de preparation

Publications (2)

Publication Number Publication Date
EA200601311A1 EA200601311A1 (ru) 2006-12-29
EA008972B1 true EA008972B1 (ru) 2007-10-26

Family

ID=34796465

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200601311A EA008972B1 (ru) 2004-01-13 2004-12-21 Новые кристаллические формы гидробромида клопидогреля и способы их получения

Country Status (3)

Country Link
EP (1) EP1713812A1 (fr)
EA (1) EA008972B1 (fr)
WO (1) WO2005068471A1 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0321256D0 (en) 2003-09-11 2003-10-08 Generics Uk Ltd Novel crystalline compounds
BRPI0510008A (pt) 2004-04-20 2007-09-18 Sanofi Aventis sal de clopidogrel e formas polimórficas deste
EP1756116A1 (fr) * 2004-04-20 2007-02-28 Sanofi-Aventis Formes polymorphes d'hydrobromure d'acetate de methyl(+)-(s)-alpha-(2-chlorophenyl)-6,7-dihydrothieno[3,2-c]pyridine-5(4h), hydrobromure de clopidrogel
EP1970054A3 (fr) 2007-03-14 2009-06-03 Ranbaxy Laboratories Limited Comprimés de clopidogrel
EP2107061A1 (fr) 2008-04-02 2009-10-07 Krka Tovarna Zdravil, D.D., Novo Mesto Procédé de préparation de clopidogrel enrichi optiquement
ES2791417T3 (es) * 2013-02-06 2020-11-04 Jingjun Huang Composición farmacéutica estable de base libre de clopidogrel para administración oral y parenteral

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003066637A1 (fr) * 2002-02-06 2003-08-14 EGIS Gyógyszergyár Rt. Polymorphes d'hydrochlorure de clopidogrel et utilisation de ceux-ci en tant que composes antithrombotiques
WO2004074215A1 (fr) * 2003-02-03 2004-09-02 Sunil Sadanand Nadkarni Procede de preparation de clopidogrel, ses sels et compositions pharmaceutiques
WO2005026174A1 (fr) * 2003-09-11 2005-03-24 Generics [Uk] Limited Polymorphes cristallins du clopidogrel

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003066637A1 (fr) * 2002-02-06 2003-08-14 EGIS Gyógyszergyár Rt. Polymorphes d'hydrochlorure de clopidogrel et utilisation de ceux-ci en tant que composes antithrombotiques
WO2004074215A1 (fr) * 2003-02-03 2004-09-02 Sunil Sadanand Nadkarni Procede de preparation de clopidogrel, ses sels et compositions pharmaceutiques
WO2005026174A1 (fr) * 2003-09-11 2005-03-24 Generics [Uk] Limited Polymorphes cristallins du clopidogrel

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CAIRA M.R.: "CRYSTALLINE POLYMORPHISM OF ORGANIC COMPOUNDS". TOPICS IN CURRENT CHEMISTRY, SPRINGER, BERLIN, DE, vol. 198, 1998, pages 163-208, XP001156954, ISSN: 0340-1022, pages 164-166 *

Also Published As

Publication number Publication date
WO2005068471A1 (fr) 2005-07-28
EP1713812A1 (fr) 2006-10-25
EA200601311A1 (ru) 2006-12-29

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM

MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): RU