DZ3246A1 - Dérivé heterocyclo-alkylsulfonyle pyrazole en tant qu'agents anti-inflammatoires/analgesiques - Google Patents
Dérivé heterocyclo-alkylsulfonyle pyrazole en tant qu'agents anti-inflammatoires/analgesiquesInfo
- Publication number
- DZ3246A1 DZ3246A1 DZ003246A DZ003246A DZ3246A1 DZ 3246 A1 DZ3246 A1 DZ 3246A1 DZ 003246 A DZ003246 A DZ 003246A DZ 003246 A DZ003246 A DZ 003246A DZ 3246 A1 DZ3246 A1 DZ 3246A1
- Authority
- DZ
- Algeria
- Prior art keywords
- heterocyclo
- inflammatory
- analgesic agents
- pyrazole derivative
- alkylsulfonyl
- Prior art date
Links
- WTKZEGDFNFYCGP-UHFFFAOYSA-N Pyrazole Chemical class C=1C=NNC=1 WTKZEGDFNFYCGP-UHFFFAOYSA-N 0.000 title 1
- 239000000730 antalgic agent Substances 0.000 title 1
- 239000002260 anti-inflammatory agent Substances 0.000 title 1
- 230000003110 anti-inflammatory effect Effects 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Diabetes (AREA)
- Immunology (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pulmonology (AREA)
- Cardiology (AREA)
- Oncology (AREA)
- Heart & Thoracic Surgery (AREA)
- Reproductive Health (AREA)
- Pregnancy & Childbirth (AREA)
- Psychology (AREA)
- Urology & Nephrology (AREA)
- Communicable Diseases (AREA)
- Hospice & Palliative Care (AREA)
- Gynecology & Obstetrics (AREA)
- Psychiatry (AREA)
- Dermatology (AREA)
- Vascular Medicine (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16870199P | 1999-12-03 | 1999-12-03 | |
| PCT/IB2000/001748 WO2001040216A1 (fr) | 1999-12-03 | 2000-11-24 | Derive heterocyclo-alkylsulfonyle pyrazole en tant qu'agents anti-inflammatoires/analgesiques |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DZ3246A1 true DZ3246A1 (fr) | 2001-06-07 |
Family
ID=22612589
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DZ003246A DZ3246A1 (fr) | 1999-12-03 | 2000-11-24 | Dérivé heterocyclo-alkylsulfonyle pyrazole en tant qu'agents anti-inflammatoires/analgesiques |
Country Status (34)
| Country | Link |
|---|---|
| US (2) | US6531492B1 (fr) |
| EP (1) | EP1233959B1 (fr) |
| JP (1) | JP2003517475A (fr) |
| KR (1) | KR20020058074A (fr) |
| CN (1) | CN1423646A (fr) |
| AP (1) | AP2002002532A0 (fr) |
| AR (1) | AR026711A1 (fr) |
| AT (1) | ATE291019T1 (fr) |
| AU (1) | AU783359B2 (fr) |
| BG (1) | BG106694A (fr) |
| BR (1) | BR0016031A (fr) |
| CA (1) | CA2392931A1 (fr) |
| CO (1) | CO5261496A1 (fr) |
| DE (1) | DE60018792T2 (fr) |
| DZ (1) | DZ3246A1 (fr) |
| EA (1) | EA200200520A1 (fr) |
| ES (1) | ES2238324T3 (fr) |
| GT (1) | GT200000204A (fr) |
| HK (1) | HK1052701A1 (fr) |
| HU (1) | HUP0300157A3 (fr) |
| IL (1) | IL149581A0 (fr) |
| IS (1) | IS6376A (fr) |
| MA (1) | MA26848A1 (fr) |
| MX (1) | MXPA02005539A (fr) |
| NO (1) | NO20022624L (fr) |
| OA (1) | OA12100A (fr) |
| PA (1) | PA8508201A1 (fr) |
| PE (1) | PE20010962A1 (fr) |
| PL (1) | PL356669A1 (fr) |
| SK (1) | SK7412002A3 (fr) |
| TN (1) | TNSN00235A1 (fr) |
| WO (1) | WO2001040216A1 (fr) |
| YU (1) | YU35102A (fr) |
| ZA (1) | ZA200204285B (fr) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6833373B1 (en) | 1998-12-23 | 2004-12-21 | G.D. Searle & Co. | Method of using an integrin antagonist and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia |
| US20040248945A1 (en) * | 1999-04-23 | 2004-12-09 | Smithkline Beecham P.L.C. | Thiazolidinedione derivative and its use as antidiabetic |
| IL149581A0 (en) * | 1999-12-03 | 2002-11-10 | Pfizer Prod Inc | Heterocyclo-alkylsulfonyl pyrazole derivatives as anti-inflammatory/analgesic agents |
| WO2003018008A1 (fr) * | 2000-02-25 | 2003-03-06 | Shionogi & Co., Ltd. | Agent d'accélération de l'expression de apo ai |
| ATE298749T1 (de) | 2001-07-05 | 2005-07-15 | Pfizer Prod Inc | Heterocyclo-alkylsulfonyl pyrazole als entzündungshemmende/analgetische mittel |
| DE10135027A1 (de) * | 2001-07-18 | 2003-02-06 | Solvay Pharm Gmbh | Verwendung Trifluoracetylalkyl-substituierter Phenyl-, Phenol- und Benzoylderivate in der Behandlung und/oder Prophylaxe von Obestias und deren Begleit- und/oder Folgeerkrankungen |
| YU67702A (sh) * | 2001-09-28 | 2004-12-31 | Pfizer Products Inc. | Postupak za dobijanje alkansulfonil piridina |
| GT200200183A (es) | 2001-09-28 | 2003-05-23 | Procedimiento para preparar derivados de heterocicloalquilsulfonil pirazol | |
| IL161462A0 (en) * | 2001-10-25 | 2004-09-27 | Novartis Ag | Combinations comprising a selective cyclooxygenase-2 inhibitor |
| BR0213763A (pt) | 2001-11-02 | 2004-10-19 | Pfizer Prod Inc | Sìntese eficiente de pirazóis contendo um heteroátomo -5 |
| WO2003037335A1 (fr) * | 2001-11-02 | 2003-05-08 | Pfizer Products Inc. | Pyrazoles substitues a 5 heteroatomes |
| WO2003037352A1 (fr) * | 2001-11-02 | 2003-05-08 | Pfizer Products Inc. | 1-phenyl-5-n-heterocyclyl-pyrazoles utiles comme inhibiteurs de cyclooxygenase pour le traitement de troubles associes a l'inflammation |
| WO2003037330A1 (fr) * | 2001-11-02 | 2003-05-08 | Pfizer Products Inc. | Sulfonylpyrazoles et sulfonyl-heteroaryl pyrazoles presentant un substituant hydrazinyle ou oxyde d'azote en position 5, servant d'inhibiteurs de la cyclooxygenase |
| WO2003037351A1 (fr) * | 2001-11-02 | 2003-05-08 | Pfizer Products Inc. | Heterocyclo-alkylsulfonyle pyrazoles et leur utilisation comme inhibiteurs de cox-2 |
| KR100686537B1 (ko) * | 2001-12-28 | 2007-02-27 | 씨제이 주식회사 | 사이클로옥시게나제-2 의 저해제로서 선택성이 뛰어난디아릴 1,2,4-트리아졸 유도체 |
| TW200403072A (en) * | 2002-01-23 | 2004-03-01 | Upjohn Co | Combination therapy for the treatment of bacterial infections |
| KR100470076B1 (ko) * | 2002-11-27 | 2005-02-05 | 씨제이 주식회사 | 1,2,4-트리아졸 유도체, 그 제조방법 및 약제학적 조성물 |
| US7247628B2 (en) * | 2002-12-12 | 2007-07-24 | Pfizer, Inc. | Cannabinoid receptor ligands and uses thereof |
| DE602004028800D1 (en) | 2003-02-07 | 2010-10-07 | Daiichi Sankyo Co Ltd | Pyrazolderivat |
| US7226930B2 (en) | 2003-04-18 | 2007-06-05 | Memory Pharmaceutical Corporation | Phosphodiesterase 4 inhibitors |
| US20050107350A1 (en) * | 2003-08-22 | 2005-05-19 | Pharmacia Corporation | Method for the treatment or prevention of bone disorders with a cyclooxygenase-2 inhibitor alone and in combination with a bone disorder treatment agent and compositions therewith |
| EP1799673A1 (fr) | 2004-10-15 | 2007-06-27 | Memory Pharmaceuticals Corporation | Derives de pyrazole utilises en tant qu'inhibiteurs de phosphodiesterase 4 |
| CN109438365B (zh) * | 2018-12-06 | 2022-04-05 | 华南师范大学 | N-(3-((4-三氟甲基)-2-嘧啶基)氨基苯基)-2,6-二氟苯磺酰胺衍生物 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PH27357A (en) | 1989-09-22 | 1993-06-21 | Fujisawa Pharmaceutical Co | Pyrazole derivatives and pharmaceutical compositions comprising the same |
| IL104311A (en) | 1992-02-05 | 1997-07-13 | Fujisawa Pharmaceutical Co | Pyrazole derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same |
| US5474995A (en) | 1993-06-24 | 1995-12-12 | Merck Frosst Canada, Inc. | Phenyl heterocycles as cox-2 inhibitors |
| US5401765A (en) | 1993-11-30 | 1995-03-28 | G. D. Searle | 1,4,5-triphenyl pyrazolyl compounds for the treatment of inflammation and inflammation-related disorders |
| US5434178A (en) | 1993-11-30 | 1995-07-18 | G.D. Searle & Co. | 1,3,5 trisubstituted pyrazole compounds for treatment of inflammation |
| US5475018A (en) | 1993-11-30 | 1995-12-12 | G. D. Searle & Co. | 1,5-diphenyl pyrazole compounds for treatment of inflammation |
| DK0923933T3 (da) | 1993-11-30 | 2002-10-21 | Searle & Co | Substituerede pyrazolyl-benzensulfonamider til anvendelse ved behandling af inflammation |
| CA2195847A1 (fr) | 1994-07-27 | 1996-02-08 | John J. Talley | Thiazoles substitues destines au traitement de l'inflammation |
| US5620999A (en) | 1994-07-28 | 1997-04-15 | Weier; Richard M. | Benzenesulfonamide subtituted imidazolyl compounds for the treatment of inflammation |
| US5585504A (en) | 1994-09-16 | 1996-12-17 | Merck & Co., Inc. | Process of making cox-2 inhibitors having a lactone bridge |
| DE69529690T2 (de) | 1994-12-21 | 2003-11-13 | Merck Frosst Canada Inc | Diaryl-2(5h)-fuaranone als cox-2-inhibitoren |
| US5691374A (en) | 1995-05-18 | 1997-11-25 | Merck Frosst Canada Inc. | Diaryl-5-oxygenated-2-(5H) -furanones as COX-2 inhibitors |
| EP0974592A4 (fr) * | 1995-09-22 | 2001-09-19 | Fujisawa Pharmaceutical Co | Nouveaux procedes de production de derives de pyridoindole |
| US5756529A (en) * | 1995-09-29 | 1998-05-26 | G.D. Searle & Co. | Substituted pyrazolyl benzenesulfonamides for use in veterinary therapies |
| GB9520584D0 (en) | 1995-10-09 | 1995-12-13 | Fujisawa Pharmaceutical Co | Pyrazole derivatives,processes for preparation thereof and pharmaceutical composition comprising the same |
| UA57002C2 (uk) | 1995-10-13 | 2003-06-16 | Мерк Фросст Кенада Енд Ко./Мерк Фросст Кенада Енд Сі. | Похідне (метилсульфоніл)феніл-2-(5н)-фуранону, фармацевтична композиція та спосіб лікування |
| EP0904269B1 (fr) | 1995-10-30 | 2002-01-23 | Merck Frosst Canada & Co. | 3,4-diaryl-2-hydroxy-2,5-dihydrofuranes utilises comme prodrogues d'inhibiteurs de cox-2 |
| IL149581A0 (en) * | 1999-12-03 | 2002-11-10 | Pfizer Prod Inc | Heterocyclo-alkylsulfonyl pyrazole derivatives as anti-inflammatory/analgesic agents |
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2000
- 2000-11-24 IL IL14958100A patent/IL149581A0/xx unknown
- 2000-11-24 HU HU0300157A patent/HUP0300157A3/hu unknown
- 2000-11-24 MX MXPA02005539A patent/MXPA02005539A/es unknown
- 2000-11-24 CA CA002392931A patent/CA2392931A1/fr not_active Abandoned
- 2000-11-24 EP EP00974741A patent/EP1233959B1/fr not_active Expired - Lifetime
- 2000-11-24 AT AT00974741T patent/ATE291019T1/de not_active IP Right Cessation
- 2000-11-24 ES ES00974741T patent/ES2238324T3/es not_active Expired - Lifetime
- 2000-11-24 WO PCT/IB2000/001748 patent/WO2001040216A1/fr active IP Right Grant
- 2000-11-24 PL PL00356669A patent/PL356669A1/xx not_active Application Discontinuation
- 2000-11-24 DZ DZ003246A patent/DZ3246A1/fr active
- 2000-11-24 EA EA200200520A patent/EA200200520A1/ru unknown
- 2000-11-24 KR KR1020027007082A patent/KR20020058074A/ko not_active Application Discontinuation
- 2000-11-24 AU AU12953/01A patent/AU783359B2/en not_active Ceased
- 2000-11-24 JP JP2001541900A patent/JP2003517475A/ja active Pending
- 2000-11-24 SK SK741-2002A patent/SK7412002A3/sk unknown
- 2000-11-24 DE DE60018792T patent/DE60018792T2/de not_active Expired - Fee Related
- 2000-11-24 YU YU35102A patent/YU35102A/sh unknown
- 2000-11-24 OA OA1200200159A patent/OA12100A/en unknown
- 2000-11-24 BR BR0016031-8A patent/BR0016031A/pt not_active IP Right Cessation
- 2000-11-24 AP APAP/P/2002/002532A patent/AP2002002532A0/en unknown
- 2000-11-24 CN CN00818329A patent/CN1423646A/zh active Pending
- 2000-11-28 US US09/724,446 patent/US6531492B1/en not_active Expired - Fee Related
- 2000-12-01 PE PE2000001289A patent/PE20010962A1/es not_active Application Discontinuation
- 2000-12-01 TN TNTNSN00235A patent/TNSN00235A1/fr unknown
- 2000-12-04 GT GT200000204A patent/GT200000204A/es unknown
- 2000-12-04 CO CO00092095A patent/CO5261496A1/es not_active Application Discontinuation
- 2000-12-04 PA PA20008508201A patent/PA8508201A1/es unknown
- 2000-12-04 AR ARP000106402A patent/AR026711A1/es unknown
-
2002
- 2002-05-10 IS IS6376A patent/IS6376A/is unknown
- 2002-05-13 BG BG106694A patent/BG106694A/xx unknown
- 2002-05-29 ZA ZA200204285A patent/ZA200204285B/en unknown
- 2002-05-31 MA MA26662A patent/MA26848A1/fr unknown
- 2002-06-03 NO NO20022624A patent/NO20022624L/no unknown
-
2003
- 2003-01-14 US US10/342,666 patent/US20030236258A1/en not_active Abandoned
- 2003-07-10 HK HK03104988.3A patent/HK1052701A1/zh unknown
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