DOP2002000481A - Derivados de acido acetico - Google Patents
Derivados de acido aceticoInfo
- Publication number
- DOP2002000481A DOP2002000481A DO2002000481A DO2002000481A DOP2002000481A DO P2002000481 A DOP2002000481 A DO P2002000481A DO 2002000481 A DO2002000481 A DO 2002000481A DO 2002000481 A DO2002000481 A DO 2002000481A DO P2002000481 A DOP2002000481 A DO P2002000481A
- Authority
- DO
- Dominican Republic
- Prior art keywords
- acetic acid
- acid derivatives
- dyslipidemias
- ppar
- computations
- Prior art date
Links
- 150000001242 acetic acid derivatives Chemical class 0.000 title abstract 2
- 208000024172 Cardiovascular disease Diseases 0.000 abstract 1
- 208000032928 Dyslipidaemia Diseases 0.000 abstract 1
- 102100038824 Peroxisome proliferator-activated receptor delta Human genes 0.000 abstract 1
- 230000003213 activating effect Effects 0.000 abstract 1
- 208000029078 coronary artery disease Diseases 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 108091008765 peroxisome proliferator-activated receptors β/δ Proteins 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 230000002685 pulmonary effect Effects 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/52—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C217/56—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms
- C07C217/58—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms with amino groups and the six-membered aromatic ring, or the condensed ring system containing that ring, bound to the same carbon atom of the carbon chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/04—Systems containing only non-condensed rings with a four-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/18—Systems containing only non-condensed rings with a ring being at least seven-membered
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10151390A DE10151390A1 (de) | 2001-10-18 | 2001-10-18 | Essigsäurederivate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DOP2002000481A true DOP2002000481A (es) | 2003-04-30 |
Family
ID=7702887
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DO2002000481A DOP2002000481A (es) | 2001-10-18 | 2002-10-08 | Derivados de acido acetico |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20050154061A1 (enExample) |
| EP (1) | EP1438285A1 (enExample) |
| JP (1) | JP2005506379A (enExample) |
| AR (1) | AR037507A1 (enExample) |
| CA (1) | CA2463226A1 (enExample) |
| DE (1) | DE10151390A1 (enExample) |
| DO (1) | DOP2002000481A (enExample) |
| GT (1) | GT200300003A (enExample) |
| PE (1) | PE20030609A1 (enExample) |
| SV (1) | SV2004001294A (enExample) |
| UY (1) | UY27491A1 (enExample) |
| WO (1) | WO2003035603A1 (enExample) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10337839A1 (de) * | 2003-08-18 | 2005-03-17 | Bayer Healthcare Ag | Indolin-Derivate |
| EP1661890B1 (en) * | 2003-09-03 | 2011-01-05 | Kowa Co., Ltd. | Ppar-activating compound and pharmaceutical composition containing same |
| DE602005024384D1 (de) | 2004-05-05 | 2010-12-09 | High Point Pharmaceuticals Llc | Neue verbindungen, ihre herstellung und verwendung |
| EP1745014B1 (en) | 2004-05-05 | 2011-07-06 | High Point Pharmaceuticals, LLC | Novel compounds, their preparation and use |
| WO2007003581A1 (en) | 2005-06-30 | 2007-01-11 | Novo Nordisk A/S | Phenoxy acetic acids as ppar delta activators |
| AU2006327003B2 (en) | 2005-12-22 | 2011-10-06 | Vtv Therapeutics Llc | Phenoxy acetic acids as PPAR delta activators |
| WO2007101864A2 (en) | 2006-03-09 | 2007-09-13 | High Point Pharmaceuticals, Llc | Compounds that modulate ppar activity, their preparation and use |
| WO2010047982A1 (en) | 2008-10-22 | 2010-04-29 | Merck Sharp & Dohme Corp. | Novel cyclic benzimidazole derivatives useful anti-diabetic agents |
| EP2362731B1 (en) | 2008-10-31 | 2016-04-06 | Merck Sharp & Dohme Corp. | Novel cyclic benzimidazole derivatives useful anti-diabetic agents |
| EP2538784B1 (en) | 2010-02-25 | 2015-09-09 | Merck Sharp & Dohme Corp. | Benzimidazole derivatives useful anti-diabetic agents |
| CA2826649C (en) | 2011-02-25 | 2016-07-26 | Merck Sharp & Dohme Corp. | Novel cyclic azabenzimidazole derivatives useful as anti-diabetic agents |
| CA2880901A1 (en) | 2012-08-02 | 2014-02-06 | Merck Sharp & Dohme Corp. | Antidiabetic tricyclic compounds |
| CN104994848A (zh) | 2013-02-22 | 2015-10-21 | 默沙东公司 | 抗糖尿病二环化合物 |
| WO2014139388A1 (en) | 2013-03-14 | 2014-09-18 | Merck Sharp & Dohme Corp. | Novel indole derivatives useful as anti-diabetic agents |
| ES2811087T3 (es) | 2013-09-09 | 2021-03-10 | Vtv Therapeutics Llc | Uso de agonistas de PPAR-delta para tratar la atrofia muscular |
| WO2015051496A1 (en) | 2013-10-08 | 2015-04-16 | Merck Sharp & Dohme Corp. | Antidiabetic tricyclic compounds |
| WO2018106518A1 (en) | 2016-12-06 | 2018-06-14 | Merck Sharp & Dohme Corp. | Antidiabetic heterocyclic compounds |
| EP3558298A4 (en) | 2016-12-20 | 2020-08-05 | Merck Sharp & Dohme Corp. | ANTIDIABETIC SPIROCHROMAN COMPOUNDS |
| WO2023147309A1 (en) | 2022-01-25 | 2023-08-03 | Reneo Pharmaceuticals, Inc. | Use of ppar-delta agonists in the treatment of disease |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9822473D0 (en) * | 1998-10-16 | 1998-12-09 | Glaxo Group Ltd | Chemical compounds |
| MXPA03002901A (es) * | 2000-10-05 | 2003-10-15 | Bayer Ag | Derivados de acido propionico. |
-
2001
- 2001-10-18 DE DE10151390A patent/DE10151390A1/de not_active Withdrawn
-
2002
- 2002-10-08 DO DO2002000481A patent/DOP2002000481A/es unknown
- 2002-10-09 CA CA002463226A patent/CA2463226A1/en not_active Abandoned
- 2002-10-09 US US10/492,761 patent/US20050154061A1/en not_active Abandoned
- 2002-10-09 JP JP2003538119A patent/JP2005506379A/ja active Pending
- 2002-10-09 EP EP02777295A patent/EP1438285A1/de not_active Withdrawn
- 2002-10-09 WO PCT/EP2002/011275 patent/WO2003035603A1/de not_active Ceased
- 2002-10-15 UY UY27491A patent/UY27491A1/es not_active Application Discontinuation
- 2002-10-17 PE PE2002001026A patent/PE20030609A1/es not_active Application Discontinuation
- 2002-10-17 SV SV2002001294A patent/SV2004001294A/es not_active Application Discontinuation
- 2002-10-18 AR ARP020103941A patent/AR037507A1/es unknown
-
2003
- 2003-01-10 GT GT200300003A patent/GT200300003A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2463226A1 (en) | 2003-05-01 |
| EP1438285A1 (de) | 2004-07-21 |
| JP2005506379A (ja) | 2005-03-03 |
| UY27491A1 (es) | 2003-05-30 |
| US20050154061A1 (en) | 2005-07-14 |
| SV2004001294A (es) | 2004-02-24 |
| AR037507A1 (es) | 2004-11-17 |
| PE20030609A1 (es) | 2003-09-07 |
| DE10151390A1 (de) | 2003-05-08 |
| WO2003035603A1 (de) | 2003-05-01 |
| GT200300003A (es) | 2004-09-21 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| UY27878A1 (es) | Derivados de indolinfenilsulfonamida | |
| DOP2002000481A (es) | Derivados de acido acetico | |
| GT200100134A (es) | Sales estables de acido o-acetilsalicilico con aminoacidos basicos | |
| PE20020884A1 (es) | 4-fluoro-n-indan-2-il-benzamida y su uso como producto farmaceutico | |
| AR033346A1 (es) | Acido aminoalcano carboxilicos, un procedimiento para su preparacion, intermediarios, y el uso de los mismos para la manufactura de un medicamento | |
| CU23208A3 (es) | Oxazolidinonas sustituidas y su uso en el campo de la coagulacion sanguinea | |
| BR0308429A (pt) | Aroilpiridinonas monocìclicas como agentes antiinflamatórios | |
| HN1999000124A (es) | Derivados de pirazol substituido. | |
| ATE381535T1 (de) | Phenethanolaminderivate | |
| UY31310A1 (es) | Ácidos 6-fenilnicotínicos sustituidos y su uso | |
| BR0211502A (pt) | Derivados de ácido acético de indano e seu uso como agentes farmacêuticos, intermediários, e método de preparação | |
| AR058098A1 (es) | Derivados de acidos dicarboxilicos y su uso | |
| CY1105127T1 (el) | Συνθεση για την προληψη καρδιαγγειακων νοσων | |
| AR022469A1 (es) | Uso de acidos isoxazolcarboxilicos sustituidos y derivados y nuevas sustancias | |
| ECSP088569A (es) | Nuevos derivados de furopirimidina acíclicos sustituidos y uso de los mismos para el tratamiento de enfermedades cardiovasculares | |
| WO2005016867A3 (en) | Anthranilic acid derivatives and their use as activators of the hm74a receptor | |
| ECSP077340A (es) | Nuevos derivados de pirimidina y su uso como moduladores del ppar-alfa | |
| UY26951A1 (es) | Derivados de ácido propiónico | |
| UY28115A1 (es) | Derivados del acido isoftalico | |
| UY30582A1 (es) | Derivados de acido 2-fenoxinicotinico y su uso | |
| PA8661701A1 (es) | Tiazolidinonas, su preparacion y su uso como medicamento | |
| AR029639A1 (es) | Amidas sustituidas del acido fenilciclohexanocarboxilico, procedimiento para su preparacion, compuestos intermediarios, medicamentos, y el uso para la manufactura de un medicamento utiles como inhibidores de la incorporacion de adenosina | |
| AR030945A1 (es) | Amidas de acido fenilciclohexanocarboxilico sustituido y su uso | |
| DOP2003000663A (es) | Derivados de indolinfenilsulfonamida | |
| UY27475A1 (es) | Amidas de ácido piperazinciclohexanocarboxílico sustituidas y su utilización |