DK666589A - D-vitamin homologer - Google Patents

D-vitamin homologer Download PDF

Info

Publication number
DK666589A
DK666589A DK666589A DK666589A DK666589A DK 666589 A DK666589 A DK 666589A DK 666589 A DK666589 A DK 666589A DK 666589 A DK666589 A DK 666589A DK 666589 A DK666589 A DK 666589A
Authority
DK
Denmark
Prior art keywords
homologist
vitamin
vitamin homologist
Prior art date
Application number
DK666589A
Other languages
Danish (da)
English (en)
Other versions
DK666589D0 (da
Inventor
Hector F Deluca
Heinrich K Schnoes
Kato L Perlman
Andrzej Kutner
Original Assignee
Wisconsin Alumni Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Res Found filed Critical Wisconsin Alumni Res Found
Publication of DK666589D0 publication Critical patent/DK666589D0/da
Publication of DK666589A publication Critical patent/DK666589A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK666589A 1988-04-29 1989-12-22 D-vitamin homologer DK666589A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/187,680 US4927815A (en) 1988-04-29 1988-04-29 Compounds effective in inducing cell differentiation and process for preparing same
PCT/US1989/001633 WO1989010353A1 (en) 1988-04-29 1989-04-18 Compounds effective in inducing cell differentiation

Publications (2)

Publication Number Publication Date
DK666589D0 DK666589D0 (da) 1989-12-22
DK666589A true DK666589A (da) 1990-02-28

Family

ID=22690003

Family Applications (2)

Application Number Title Priority Date Filing Date
DK666589A DK666589A (da) 1988-04-29 1989-12-22 D-vitamin homologer
DK91890A DK89091D0 (da) 1988-04-29 1991-05-13 Fremgangsmaade til fremstilling af vitamin-d-forbindelser

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK91890A DK89091D0 (da) 1988-04-29 1991-05-13 Fremgangsmaade til fremstilling af vitamin-d-forbindelser

Country Status (15)

Country Link
US (2) US4927815A (forum.php)
EP (1) EP0375757A1 (forum.php)
JP (2) JPH0725730B2 (forum.php)
KR (1) KR930011151B1 (forum.php)
AU (1) AU630096B2 (forum.php)
CA (1) CA1340615C (forum.php)
DK (2) DK666589A (forum.php)
FR (1) FR2630740A1 (forum.php)
GB (1) GB2217715A (forum.php)
HU (1) HU206083B (forum.php)
IE (1) IE67868B1 (forum.php)
IL (1) IL90066A (forum.php)
IN (1) IN170659B (forum.php)
NL (1) NL8920414A (forum.php)
WO (1) WO1989010353A1 (forum.php)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5250523A (en) * 1988-04-29 1993-10-05 Wisconsin Alumni Research Foundation Side chain unsaturated 1α-hydroxyvitanim D homologs
CA1339383C (en) * 1989-03-09 1997-08-26 Hector Floyd Deluca Method for preparing intermediates for the synthesis of steroid side chains in optically active form
DE3933034A1 (de) * 1989-10-02 1991-04-11 Schering Ag 24-homo-vitamin-d-derivate, verfahren zu ihrer herstellung
GB9007236D0 (en) * 1990-03-30 1990-05-30 Leo Pharm Prod Ltd Chemical compounds
RU2123338C1 (ru) * 1990-06-15 1998-12-20 Сайтел Корпорейшн Фармацевтическая композиция на основе медиатора межклеточной адгезии (варианты), способ ингибирования межклеточной адгезии, способ лечения воспалительного заболевания, способ анализа тестируемого соединения на способность ингибировать клеточную адгезию, способ получения соединения
US5459136A (en) * 1990-08-24 1995-10-17 Wisconsin Alumni Research Foundation Methods using vitamin D compounds for improvement of skin conditions
US5276061A (en) * 1990-08-24 1994-01-04 Wisconsin Alumni Research Foundation Cosmetic compositions containing 1α-hydroxyvitamin D homologs
US5756783A (en) * 1990-09-21 1998-05-26 Bone Care International, Inc. 1α-Hydroxy-24-EPI-vitamin D4
DE4221961A1 (de) * 1992-06-30 1994-01-05 Schering Ag 22-En-25-oxa-Derivate in der Vitamin D-Reihe, Verfahren zu ihrer Herstellung, diese Derivate enthaltenen pharmazeutische Präparate sowie deren Verwendung als Arzneimittel
US5380720A (en) * 1993-05-11 1995-01-10 Wisconsin Alumni Research Foundation Iodo vitamin D3 compounds and method for preparing same
RU2141318C1 (ru) * 1993-12-01 1999-11-20 Санкио Компани Лимитед Ингибитор образования воспалительного цитокина, средство для профилактики и лечения воспалительных заболеваний пищеварительного тракта и синдрома бехчета, способ профилактики и лечения воспалительных заболеваний и язвенного колита
PE28297A1 (es) * 1995-01-26 1997-08-20 Hoffmann La Roche Empleo dermatologico de derivados de vitamina d
US5744128A (en) * 1995-05-03 1998-04-28 Holick; Michael F. Use of emu oil for stimulating skin and hair growth
CA2175881A1 (en) * 1995-05-09 1996-11-10 Andrzej Kutner Vitamin d compounds and methods of preparing these compounds
AUPO727097A0 (en) * 1997-06-10 1997-07-03 Unisearch Limited Method of treatment of hepatoma and pharmaceutical compositions for use therein
ES2368824T3 (es) * 1998-03-27 2011-11-22 Oregon Health & Science University Vitamina d y sus análogos en el tratamiento de tumores y otros desórdenes hiperproliferativos.
CA2366586C (en) * 1999-04-01 2004-06-22 Johns Hopkins University Non-calcemic, antiproliferative, transcriptionally active sulfur-containing analogs of 1.alpha., 25-dihydroxy vitamin d3
WO2001040177A2 (en) 1999-12-02 2001-06-07 Women And Infants Hospital Esters of vitamin d3 and uses thereof
US7166585B2 (en) * 2001-08-22 2007-01-23 Cytochroma Inc. 24-Sulfur-substituted analogs of 1α,25-dihydroxy vitamin D3
WO2003087048A2 (en) * 2002-04-11 2003-10-23 Instytut Farmaceutyczny Preparation of 24 alkyl analogs of cholecalciferol and non-racemic compounds
BRPI0508333A (pt) * 2004-03-01 2007-07-17 Bioxell Spa uso de um composto de vitamina d, método de prevenir e/ou tratar cistite intersticial, formulação farmacêutica, composto de vitamina d, e, kit
EP1812011A1 (en) 2004-11-12 2007-08-01 Bioxell S.p.a. Combined use of vitamin d derivatives and anti-proliferative agents for treating bladder cancer
WO2008131267A2 (en) * 2007-04-18 2008-10-30 Johns Hopkins University Low calcemic, highly antiproliferative, analogs of calcitriol
CA2981549A1 (en) 2009-01-27 2010-08-05 Berg Llc Vitamin d3 and analogs thereof for alleviating side effects associated with chemotherapy
EA201270226A1 (ru) 2009-08-14 2012-09-28 БЕРГ БАЙОСИСТЕМЗ, ЭлЭлСи Витамин d3 и его аналогии для лечения алопеции
US8754067B2 (en) 2010-11-12 2014-06-17 Wisconsin Alumni Research Foundation 22-haloacetoxy-homopregnacalciferol analogs and their uses
NZ714801A (en) 2013-05-29 2021-07-30 Berg Llc Preventing or mitigating chemotherapy induced alopecia using vitamin d
CN110981765A (zh) * 2019-11-07 2020-04-10 肇庆巨元生化有限公司 一种25-羟基维生素d3中间体的制备方法
CN112920096A (zh) * 2019-12-05 2021-06-08 四川大学 一种制备2-甲基-4-(苯磺酰基)-2-丁醇的方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62500301A (ja) * 1984-10-04 1987-02-05 ウイスコンシン　アラムナイ　リサ−チ　フオンデ−シヨン ２４―ホモビタミンｄ誘導体
WO1986004333A1 (en) * 1985-01-17 1986-07-31 Wisconsin Alumni Research Foundation Vitamin d derivatives and methods for preparing same
US4717721A (en) * 1985-05-30 1988-01-05 Howard W. Bremer Sidechain homo-vitamin D compounds with preferential anti-cancer activity
IL77668A (en) * 1986-01-21 1989-03-31 Teva Pharma Production of cholecalciferol derivatives and novel intermediates used therefor
US4804502A (en) * 1988-01-20 1989-02-14 Hoffmann-La Roche Inc. Vitamin D compounds
US5206229A (en) * 1988-04-21 1993-04-27 Leo Pharmaceutical Products Ltd Vitamin d analogues
AU629831B2 (en) * 1988-04-29 1992-10-15 Wisconsin Alumni Research Foundation Side chain unsaturated 1 alpha-hydroxyvitamin d homologs for the treatment of leukemia

Also Published As

Publication number Publication date
IL90066A (en) 1995-12-08
IN170659B (forum.php) 1992-05-02
CA1340615C (en) 1999-06-29
IE891406L (en) 1989-10-29
DK89091A (da) 1991-05-13
IE67868B1 (en) 1996-05-01
EP0375757A1 (en) 1990-07-04
JPH0748343A (ja) 1995-02-21
IL90066A0 (en) 1989-12-15
HUT52475A (en) 1990-07-28
US5061699A (en) 1991-10-29
KR930011151B1 (ko) 1993-11-24
FR2630740A1 (fr) 1989-11-03
DK89091D0 (da) 1991-05-13
JPH02504154A (ja) 1990-11-29
GB8909570D0 (en) 1989-06-14
KR900700449A (ko) 1990-08-13
JP2505713B2 (ja) 1996-06-12
GB2217715A (en) 1989-11-01
NL8920414A (nl) 1990-04-02
JPH0725730B2 (ja) 1995-03-22
US4927815A (en) 1990-05-22
HU206083B (en) 1992-08-28
AU3573089A (en) 1989-11-24
AU630096B2 (en) 1992-10-22
WO1989010353A1 (en) 1989-11-02
DK666589D0 (da) 1989-12-22
HU892989D0 (en) 1990-06-28

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